Zobrazeno 1 - 10
of 470
pro vyhledávání: '"Martin, Kuiper"'
Autor:
Anna Niarakis, Marek Ostaszewski, Alexander Mazein, Inna Kuperstein, Martina Kutmon, Marc E. Gillespie, Akira Funahashi, Marcio Luis Acencio, Ahmed Hemedan, Michael Aichem, Karsten Klein, Tobias Czauderna, Felicia Burtscher, Takahiro G. Yamada, Yusuke Hiki, Noriko F. Hiroi, Finterly Hu, Nhung Pham, Friederike Ehrhart, Egon L. Willighagen, Alberto Valdeolivas, Aurelien Dugourd, Francesco Messina, Marina Esteban-Medina, Maria Peña-Chilet, Kinza Rian, Sylvain Soliman, Sara Sadat Aghamiri, Bhanwar Lal Puniya, Aurélien Naldi, Tomáš Helikar, Vidisha Singh, Marco Fariñas Fernández, Viviam Bermudez, Eirini Tsirvouli, Arnau Montagud, Vincent Noël, Miguel Ponce-de-Leon, Dieter Maier, Angela Bauch, Benjamin M. Gyori, John A. Bachman, Augustin Luna, Janet Piñero, Laura I. Furlong, Irina Balaur, Adrien Rougny, Yohan Jarosz, Rupert W. Overall, Robert Phair, Livia Perfetto, Lisa Matthews, Devasahayam Arokia Balaya Rex, Marija Orlic-Milacic, Luis Cristobal Monraz Gomez, Bertrand De Meulder, Jean Marie Ravel, Bijay Jassal, Venkata Satagopam, Guanming Wu, Martin Golebiewski, Piotr Gawron, Laurence Calzone, Jacques S. Beckmann, Chris T. Evelo, Peter D’Eustachio, Falk Schreiber, Julio Saez-Rodriguez, Joaquin Dopazo, Martin Kuiper, Alfonso Valencia, Olaf Wolkenhauer, Hiroaki Kitano, Emmanuel Barillot, Charles Auffray, Rudi Balling, Reinhard Schneider, the COVID-19 Disease Map Community
Publikováno v:
Frontiers in Immunology, Vol 14 (2024)
IntroductionThe COVID-19 Disease Map project is a large-scale community effort uniting 277 scientists from 130 Institutions around the globe. We use high-quality, mechanistic content describing SARS-CoV-2-host interactions and develop interoperable b
Externí odkaz:
https://doaj.org/article/ac53015acf3143cf9c3f232ae67ad161
Publikováno v:
iScience, Vol 27, Iss 2, Pp 108859- (2024)
Summary: Psoriasis arises from complex interactions between keratinocytes and immune cells, leading to uncontrolled inflammation, immune hyperactivation, and a perturbed keratinocyte life cycle. Despite the availability of drugs for psoriasis managem
Externí odkaz:
https://doaj.org/article/d6dae4fee041422ea0b143a4fd6f6ddc
Autor:
Åsmund Flobak, John Zobolas, Miguel Vazquez, Tonje S. Steigedal, Liv Thommesen, Asle Grislingås, Barbara Niederdorfer, Evelina Folkesson, Martin Kuiper
Publikováno v:
Frontiers in Systems Biology, Vol 3 (2023)
Treatment with combinations of drugs carries great promise for personalized therapy for a variety of diseases. We have previously shown that synergistic combinations of cancer signaling inhibitors can be identified based on a logical framework, by ma
Externí odkaz:
https://doaj.org/article/aaa85615ca6e41e4903f1202121a5938
Publikováno v:
FEBS Open Bio, Vol 13, Iss 1, Pp 143-153 (2023)
A hallmark of the development of solid and hematological malignancies is the dysregulation of apoptosis, which leads to an imbalance between cell proliferation, cell survival and death. Halogenated boroxine [K2(B3O3F4OH)] (HB) is a derivative of cycl
Externí odkaz:
https://doaj.org/article/d76e81d17cdb425686271347d68a23a6
Autor:
Wim De Mulder, Martin Kuiper
Publikováno v:
BMC Bioinformatics, Vol 21, Iss 1, Pp 1-11 (2020)
Abstract Background Treating patients with combinations of drugs that have synergistic effects has become widespread practice in the clinic. Drugs work synergistically when the observed effect of a drug combination is larger than the effect predicted
Externí odkaz:
https://doaj.org/article/7b161fa49a2e40288435697b4dc20a4e
Publikováno v:
iScience, Vol 24, Iss 12, Pp 103451- (2021)
Summary: Psoriasis is a chronic skin disease, in which immune cells and keratinocytes keep each other in a state of inflammation. It is believed that phospholipase A2 (PLA2)-dependent eicosanoid release plays a key role in this. T-helper (Th) 1-deriv
Externí odkaz:
https://doaj.org/article/4bc0bef92b5a41eba07fd5930063ec08
Autor:
Kathleen A. Heck, Håvard T. Lindholm, Barbara Niederdorfer, Eirini Tsirvouli, Martin Kuiper, Åsmund Flobak, Astrid Lægreid, Liv Thommesen
Publikováno v:
Proteomes, Vol 11, Iss 1, p 3 (2023)
Colorectal cancer (CRC) is one of the most prevalent cancers, driven by several factors including deregulations in intracellular signalling pathways. Small extracellular vesicles (sEVs) are nanosized protein-packaged particles released from cells, wh
Externí odkaz:
https://doaj.org/article/750dbd6bcab14f79b3d6cdf8f74b1b95
Autor:
Eirini Tsirvouli, Vasundra Touré, Barbara Niederdorfer, Miguel Vázquez, Åsmund Flobak, Martin Kuiper
Publikováno v:
Frontiers in Molecular Biosciences, Vol 7 (2020)
Cancer is a heterogeneous and complex disease and one of the leading causes of death worldwide. The high tumor heterogeneity between individuals affected by the same cancer type is accompanied by distinct molecular and phenotypic tumor profiles and v
Externí odkaz:
https://doaj.org/article/bdd93abe57db4dc78f1a71bca6fcf585
Autor:
Barbara Niederdorfer, Vasundra Touré, Miguel Vazquez, Liv Thommesen, Martin Kuiper, Astrid Lægreid, Åsmund Flobak
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
Discrete dynamical modeling shows promise in prioritizing drug combinations for screening efforts by reducing the experimental workload inherent to the vast numbers of possible drug combinations. We have investigated approaches to predict combination
Externí odkaz:
https://doaj.org/article/9646a10c30a64b28b8fde52fa58f74b4
Publikováno v:
FEBS Open Bio
A hallmark of the development of solid and hematological malignancies is the dysregulation of apoptosis, which leads to an imbalance between cell proliferation, cell survival and death. Halogenated boroxine [K2(B3O3F4OH)] (HB) is a derivative of cycl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3582fcdefc49144cb6107b6dc4cd9ab8
https://doi.org/10.1002/2211-5463.13522
https://doi.org/10.1002/2211-5463.13522