Zobrazeno 1 - 10
of 511
pro vyhledávání: '"Martin, Kolb"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Assessment of lung function is an important clinical tool for the diagnosis and monitoring of chronic lung diseases, including idiopathic pulmonary fibrosis (IPF). In mice, lung function maneuvers use algorithm-based ventilation strategies i
Externí odkaz:
https://doaj.org/article/df22953c84d64e2fac490c68944354ee
Autor:
Franziska Roeder, Tina Röpke, Lara-Kristin Steinmetz, Martin Kolb, Ulrich A. Maus, Bradford J. Smith, Lars Knudsen
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract Pre-injured lungs are prone to injury progression in response to mechanical ventilation. Heterogeneous ventilation due to (micro)atelectases imparts injurious strains on open alveoli (known as volutrauma). Hence, recruitment of (micro)atelec
Externí odkaz:
https://doaj.org/article/4cb35dbb795c4470a64393acdd535155
Autor:
Deborah Assayag, Julie Morisset, Jolene H Fisher, Hélène Manganas, Christopher J Ryerson, Martin Kolb, Kerri Johannson, Mira A Donaldson, Kathryn Donohoe, Celine Durand, Stacey D Lok, Veronica Marcoux, Bohyung Min, Daniel-Costin Marinescu
Publikováno v:
BMJ Open Respiratory Research, Vol 11, Iss 1 (2024)
Background Fibrotic interstitial lung disease (ILD) is frequently associated with abnormal oxygenation; however, little is known about the accuracy of oxygen saturation by pulse oximetry (SpO2) compared with arterial blood gas (ABG) saturation (SaO2)
Externí odkaz:
https://doaj.org/article/7e2f02956af44aa88ec56c1a83e4b1df
Autor:
Elizabeth R. Volkmann, Christopher P. Denton, Martin Kolb, Marlies S. Wijsenbeek-Lourens, Claire Emson, Krischan Hudson, Anthony J. Amatucci, Oliver Distler, Yannick Allanore, Dinesh Khanna
Publikováno v:
European Respiratory Review, Vol 33, Iss 172 (2024)
Lysophosphatidic acid (LPA)-mediated activation of LPA receptor 1 (LPAR1) contributes to the pathophysiology of fibrotic diseases such as idiopathic pulmonary fibrosis (IPF) and systemic sclerosis (SSc). These diseases are associated with high morbid
Externí odkaz:
https://doaj.org/article/7dad0459aeb649318b278eb58358677c
Autor:
Yongfeng Luo, Ke Cao, Joanne Chiu, Hui Chen, Hong-Jun Wang, Matthew E Thornton, Brendan H Grubbs, Martin Kolb, Michael S Parmacek, Yuji Mishina, Wei Shi
Publikováno v:
eLife, Vol 12 (2024)
Abnormal lung development can cause congenital pulmonary cysts, the mechanisms of which remain largely unknown. Although the cystic lesions are believed to result directly from disrupted airway epithelial cell growth, the extent to which developmenta
Externí odkaz:
https://doaj.org/article/310cc91eef7547f0b2c6ff8d0cb9222f
Autor:
Kirsten Nesset, Martin Kolb
Publikováno v:
Jornal Brasileiro de Pneumologia, Vol 50, Iss 1 (2024)
Externí odkaz:
https://doaj.org/article/007f5e49c63f46279eacdf964c1b9fd9
Autor:
Paola Muti, Andrea Sacconi, Claudio Pulito, Giulia Orlandi, Sara Donzelli, Aldo Morrone, James Jiulian, Gerard P. Cox, Martin Kolb, Gregory Pond, Peter Kavsak, Mark Norman Levine, Giovanni Blandino, Sabrina Strano
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-12 (2022)
Abstract Background Malignant pleural mesothelioma is a highly aggressive tumor associated with asbestos exposure. There are few effective treatment options for mesothelioma, and patients have a very poor prognosis. Mesothelioma has the potential to
Externí odkaz:
https://doaj.org/article/881490acf3754d43aca0d1fbffd35fcd
Autor:
Tina Bormann, Regina Maus, Jennifer Stolper, Meritxell Tort Tarrés, Christina Brandenberger, Dirk Wedekind, Danny Jonigk, Tobias Welte, Jack Gauldie, Martin Kolb, Ulrich A. Maus
Publikováno v:
Respiratory Research, Vol 23, Iss 1, Pp 1-12 (2022)
Abstract Background Idiopathic pulmonary fibrosis (IPF) is a diffuse parenchymal lung disease characterized by exuberant deposition of extracellular matrix (ECM) proteins in the lung interstitium, which contributes to substantial morbidity and mortal
Externí odkaz:
https://doaj.org/article/21db241c974f480aaaa03111058bc8f0
Autor:
Abdullah Sakkat, Gerard Cox, Nader Khalidi, Maggie Larche, Karen Beattie, Elisabetta A. Renzoni, Nilesh Morar, Vasilis Kouranos, Martin Kolb, Nathan Hambly
Publikováno v:
Respiratory Research, Vol 23, Iss 1, Pp 1-9 (2022)
Abstract Background Infliximab is a monoclonal antibody that binds and neutralizes circulating tumor necrosis factor-alpha, a key inflammatory cytokine in the pathophysiology of sarcoidosis. Despite the paucity of randomized clinical trials, inflixim
Externí odkaz:
https://doaj.org/article/1486a4ddd15f44bdabfbfcf9e7083258
Autor:
Alyson W Wong, Huiying Sun, Ingrid A Cox, Jolene H Fisher, Nasreen Khalil, Kerri A Johannson, Veronica Marcoux, Deborah Assayag, Helene Manganas, Martin Kolb, Andrew J Palmer, Barbara de Graaff, E Haydn Walters, Peter Hopkins, Christopher Zappala, Nicole S Goh, Yuben Moodley, Vidya Navaratnam, Tamera J Corte, Christopher J Ryerson, Wei Zhang
Publikováno v:
PLoS ONE, Vol 18, Iss 3, p e0283110 (2023)
ObjectivesFibrotic interstitial lung disease (ILD) includes a large group of conditions that lead to scarring of the lungs. The lack of available 5-level EuroQol 5D (EQ5D) data has limited the ability to conduct economic evaluations in ILD. The purpo
Externí odkaz:
https://doaj.org/article/15fdc94987af468a80bd1f82ad217002