Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Martin, Kenward"'
Publikováno v:
Biophysical Journal. 99(10):3355-3364
We present a Monte Carlo simulation study of the distribution and propagation of twist from one DNA linker to another for a two-nucleosome array subjected to externally applied twist. A mesoscopic model of the array that incorporates nucleosome geome
Publikováno v:
Microfluidics and Nanofluidics. 6:121-130
Polymerase chain reaction (PCR) in a microfluidic Rayleigh–Benard convection cell represents a promising route towards portable PCR for point-of-care uses. In the present contribution, the coupled fluid mechanics and heat transport processes are so
Publikováno v:
Polymer. 45:1223-1234
We present data showing a substantial narrowing of the polydispersity index (PDI) of high polymers occurring as a consequence of random chain scission events in a transient elongational flow field. In our experiments, semi-dilute aqueous solutions of
Publikováno v:
Soft Materials. 1:365-391
From the forthcoming book, Soft Materials: Structure, and Dynamics, Marangoni, A. G. and Dutcher, J., Eds., Marcel Dekker, Inc., in press.
Publikováno v:
Current Opinion in Biotechnology. 14:58-64
The Human Genome has been sequenced in large part owing to the invention of capillary electrophoresis. Although this technology has matured enough to allow such amazing achievements, the physical mechanisms at play during separation have yet to be co
Autor:
Jean-Francois Mercier, Gary W. Slater, Steve Guillouzic, Michael G. Gauthier, Laurette C. McCormick, Frédéric Tessier, Martin Kenward
Publikováno v:
ELECTROPHORESIS. 23:3791-3816
Over the last two decades, the introduction of new methods such as pulsed-field gel electrophoresis and capillary array electrophoresis has made it possible to map and sequence entire genomes, including our own. The development of these experimental
Publikováno v:
BMC Biophysics, Vol 4, Iss 1, p 8 (2011)
BMC Biophysics
Iyer, Balaji VS; Kenward, Martin; & Arya, Gaurav. (2011). Hierarchies in Eukaryotic Genome Organization: Insights from Polymer Theory and Simulations. BMC Biophysics, 4(1), 8. doi: http://dx.doi.org/10.1186/2046-1682-4-8. Retrieved from: http://www.escholarship.org/uc/item/7t4911st
BMC Biophysics
Iyer, Balaji VS; Kenward, Martin; & Arya, Gaurav. (2011). Hierarchies in Eukaryotic Genome Organization: Insights from Polymer Theory and Simulations. BMC Biophysics, 4(1), 8. doi: http://dx.doi.org/10.1186/2046-1682-4-8. Retrieved from: http://www.escholarship.org/uc/item/7t4911st
Eukaryotic genomes possess an elaborate and dynamic higher-order structure within the limiting confines of the cell nucleus. Knowledge of the physical principles and the molecular machinery that govern the 3D organization of this structure and its re
Autor:
Kevin D. Dorfman, Martin Kenward
Deoxyribozymes (DNAzymes) are single-stranded DNA that catalyze nucleic acid biochemistry. Although a number of DNAzymes have been discovered by in vitro selection, the relationship between their tertiary structure and function remains unknown. We fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45425ff29c555e0e542ade3d3d538f3c
https://europepmc.org/articles/PMC2776252/
https://europepmc.org/articles/PMC2776252/
Publikováno v:
Electrophoresis. 30(9)
We present an approach for merging boundary element method (BEM) solutions of the electric field in electrically insulating complex geometries with Brownian dynamics (BD) simulations of DNA electrophoresis therein. Although a rote application of the