Zobrazeno 1 - 10
of 287
pro vyhledávání: '"Martin, K M"'
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract For most proteins annotated as enzymes, it is unknown which primary and/or secondary reactions they catalyze. Experimental characterizations of potential substrates are time-consuming and costly. Machine learning predictions could provide an
Externí odkaz:
https://doaj.org/article/9a14800df9344922b342fa032ed19bcb
Autor:
Veronica Gast, Anna Sandegren, Finn Dunås, Siri Ekblad, Rezan Güler, Staffan Thorén, Marta Tous Mohedano, Mikael Molin, Martin K. M. Engqvist, Verena Siewers
Publikováno v:
Microbial Cell Factories, Vol 21, Iss 1, Pp 1-15 (2022)
Abstract Background Affibody molecules are synthetic peptides with a variety of therapeutic and diagnostic applications. To date, Affibody molecules have mainly been produced by the bacterial production host Escherichia coli. There is an interest in
Externí odkaz:
https://doaj.org/article/97741660c2d64e549d4f8423f1d14931
Autor:
Wanrooij, Paulina H., Tran, Phong, Thompson, Liam J., Carvalho, Gustavo, Sharma, Sushma, Kreisel, Katrin, Navarrete, Clara, Feldberg, Anna-Lena, Watt, Danielle L., Nilsson, Anna Karin, Engqvist, Martin K. M., Clausen, Anders R., Chabes, Andrei
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2020 Jun . 117(25), 14306-14313.
Externí odkaz:
https://www.jstor.org/stable/26934959
Publikováno v:
Biotechnology for Biofuels, Vol 14, Iss 1, Pp 1-18 (2021)
Abstract Background Ascomycetous yeasts from the kingdom fungi inhabit every biome in nature. While filamentous fungi have been studied extensively regarding their enzymatic degradation of the complex polymers comprising lignocellulose, yeasts have b
Externí odkaz:
https://doaj.org/article/43b23a0811144614899d35e588aca50e
Publikováno v:
ACS Omega, Vol 6, Iss 3, Pp 1985-1990 (2021)
Externí odkaz:
https://doaj.org/article/68a4fe462e9e4d3c8f360a077951f1a0
Publikováno v:
PLoS Biology, Vol 19, Iss 10, p e3001402 (2021)
The Michaelis constant KM describes the affinity of an enzyme for a specific substrate and is a central parameter in studies of enzyme kinetics and cellular physiology. As measurements of KM are often difficult and time-consuming, experimental estima
Externí odkaz:
https://doaj.org/article/e744724226e24f99b89ce9de3626d7c7
Autor:
Elzbieta Rembeza, Martin K M Engqvist
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 9, p e1009446 (2021)
Only a small fraction of genes deposited to databases have been experimentally characterised. The majority of proteins have their function assigned automatically, which can result in erroneous annotations. The reliability of current annotations in pu
Externí odkaz:
https://doaj.org/article/9d656493b80a40cea28c4f707d8fb1a1
Autor:
Qi Qi, Feiran Li, Rosemary Yu, Martin K. M. Engqvist, Verena Siewers, Johannes Fuchs, Jens Nielsen
Publikováno v:
mBio, Vol 11, Iss 6 (2020)
ABSTRACT Protein folding is often considered the flux controlling process in protein synthesis and secretion. Here, two previously isolated Saccharomyces cerevisiae strains with increased α-amylase productivity were analyzed in chemostat cultures at
Externí odkaz:
https://doaj.org/article/ef879989345f40879de143a94eb6b15d
Autor:
Martin K. M. Engqvist
Publikováno v:
BMC Microbiology, Vol 18, Iss 1, Pp 1-14 (2018)
Abstract Background The ambient temperature of all habitats is a key physical property that shapes the biology of microbes inhabiting them. The optimal growth temperature (OGT) of a microbe, is therefore a key piece of data needed to understand evolu
Externí odkaz:
https://doaj.org/article/3b8e1b55271e4de389fbe9c4b3f8f52e
Autor:
Wanrooij, Paulina H., Engqvist, Martin K. M., Forslund, Josefin M. E., Navarrete, Clara, Nilsson, Anna Karin, Sedman, Juhan, Wanrooij, Sjoerd, Clausen, Anders R., Chabes, Andrei
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2017 Nov . 114(47), 12466-12471.
Externí odkaz:
https://www.jstor.org/stable/26485595