Zobrazeno 1 - 10
of 315
pro vyhledávání: '"Martin, Köbel"'
Autor:
Maryam Asadi-Aghbolaghi, Amirali Darbandsari, Allen Zhang, Alberto Contreras-Sanz, Jeffrey Boschman, Pouya Ahmadvand, Martin Köbel, David Farnell, David G. Huntsman, Andrew Churg, Peter C. Black, Gang Wang, C. Blake Gilks, Hossein Farahani, Ali Bashashati
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-18 (2024)
Abstract Investigation of histopathology slides by pathologists is an indispensable component of the routine diagnosis of cancer. Artificial intelligence (AI) has the potential to enhance diagnostic accuracy, improve efficiency, and patient outcomes
Externí odkaz:
https://doaj.org/article/72c28cf50b92406fb499cf977e8ae969
Autor:
Gurdial Dhillon, Marta Llaurado-Fernandez, Basile Tessier-Cloutier, Keiyan Sy, Dina Bassiouny, Guangming Han, Nelson K. Y. Wong, Kathryn McRae, Mary Kinloch, Jennifer Pors, Laura Hopkins, Allan Covens, Martin Köbel, Cheng-Han Lee, Mark S. Carey
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
ObjectivesOvarian carcinosarcoma (OCS) is a rare and lethal type of ovarian cancer. Despite its incredibly poor prognosis, it has received little research attention. In this study, we aim to evaluate the molecular features of OCS and elucidate their
Externí odkaz:
https://doaj.org/article/1bc2f2281c6b4423b0904ef00b3bc3bc
Publikováno v:
Gynecologic Oncology Reports, Vol 54, Iss , Pp 101447- (2024)
Objective: This study aims to investigate the relationship between body mass index (BMI) and molecular subtypes of endometrial carcinoma using an immunohistochemistry (IHC)-based classification approach. Methods: We analyzed a consecutive series of e
Externí odkaz:
https://doaj.org/article/ce3a2646014d4b85b19368b9fdd1f0eb
Autor:
Martin Köbel, Eun Young Kang, Sandra Lee, Travis Ogilvie, Tatjana Terzic, Linyuan Wang, Nicholas JP Wiebe, Zainab Al‐Shamma, Linda S Cook, Gregg S Nelson, Colin JR Stewart, Andreas von Deimling, Felix KF Kommoss, Cheng‐Han Lee
Publikováno v:
The Journal of Pathology: Clinical Research, Vol 10, Iss 4, Pp n/a-n/a (2024)
Abstract Mesonephric‐type (or ‐like) adenocarcinomas (MAs) of the ovary are an uncommon and aggressive histotype. They appear to arise through transdifferentiation from Müllerian lesions creating diagnostic challenges. Thus, we aimed to develop
Externí odkaz:
https://doaj.org/article/23c3f883b25346dd86e6dc988795d9f1
Autor:
Martin Köbel, Eun‐Young Kang, Ashley Weir, Peter F Rambau, Cheng‐Han Lee, Gregg S Nelson, Prafull Ghatage, Nicola S Meagher, Marjorie J Riggan, Jennifer Alsop, Michael S Anglesio, Matthias W Beckmann, Christiani Bisinotto, Michelle Boisen, Jessica Boros, Alison H Brand, Angela Brooks‐Wilson, Michael E Carney, Penny Coulson, Madeleine Courtney‐Brooks, Kara L Cushing‐Haugen, Cezary Cybulski, Suha Deen, Mona A El‐Bahrawy, Esther Elishaev, Ramona Erber, Sian Fereday, AOCS Group, Anna Fischer, Simon A Gayther, Arantzazu Barquin‐Garcia, Aleksandra Gentry‐Maharaj, C Blake Gilks, Helena Gronwald, Marcel Grube, Paul R Harnett, Holly R Harris, Andreas D Hartkopf, Arndt Hartmann, Alexander Hein, Joy Hendley, Brenda Y Hernandez, Yajue Huang, Anna Jakubowska, Mercedes Jimenez‐Linan, Michael E Jones, Catherine J Kennedy, Tomasz Kluz, Jennifer M Koziak, Jaime Lesnock, Jenny Lester, Jan Lubiński, Teri A Longacre, Maria Lycke, Constantina Mateoiu, Bryan M McCauley, Valerie McGuire, Britta Ney, Alexander Olawaiye, Sandra Orsulic, Ana Osorio, Luis Paz‐Ares, Teresa Ramón y Cajal, Joseph H Rothstein, Matthias Ruebner, Minouk J Schoemaker, Mitul Shah, Raghwa Sharma, Mark E Sherman, Yurii B Shvetsov, Naveena Singh, Helen Steed, Sarah J Storr, Aline Talhouk, Nadia Traficante, Chen Wang, Alice S Whittemore, Martin Widschwendter, Lynne R Wilkens, Stacey J Winham, Javier Benitez, Andrew Berchuck, David D Bowtell, Francisco J Candido dos Reis, Ian Campbell, Linda S Cook, Anna DeFazio, Jennifer A Doherty, Peter A Fasching, Renée T Fortner, María J García, Marc T Goodman, Ellen L Goode, Jacek Gronwald, David G Huntsman, Beth Y Karlan, Linda E Kelemen, Stefan Kommoss, Nhu D Le, Stewart G Martin, Usha Menon, Francesmary Modugno, Paul DP Pharoah, Joellen M Schildkraut, Weiva Sieh, Annette Staebler, Karin Sundfeldt, Anthony J Swerdlow, Susan J Ramus, James D Brenton
Publikováno v:
The Journal of Pathology: Clinical Research, Vol 9, Iss 3, Pp 208-222 (2023)
Abstract Our objective was to test whether p53 expression status is associated with survival for women diagnosed with the most common ovarian carcinoma histotypes (high‐grade serous carcinoma [HGSC], endometrioid carcinoma [EC], and clear cell carc
Externí odkaz:
https://doaj.org/article/493c5874781345c8971b7e798d52a02b
Autor:
Gerbrand Zoet, Dwayne R. Tucker, Natasha L. Orr, Fahad T. Alotaibi, Yang Doris Liu, Heather Noga, Martin Köbel, Paul J. Yong
Publikováno v:
Frontiers in Reproductive Health, Vol 5 (2023)
IntroductionWe propose a standardized protocol for measurement of nerve bundle density in endometriosis as a potential biomarker, including in deep endometriosis (DE), ovarian endometriomas (OMA) and superficial peritoneal endometriosis (SUP).Methods
Externí odkaz:
https://doaj.org/article/583bfd1e768841d9a41f54a9a73f3d51
Autor:
Dane Cheasley, Marta Llaurado Fernandez, Martin Köbel, Hannah Kim, Amy Dawson, Joshua Hoenisch, Madison Bittner, Derek S. Chiu, Aline Talhouk, C. Blake Gilks, Madawa W. Jayawardana, Kathleen I. Pishas, Anne-Marie Mes-Masson, Diane Provencher, Abhimanyu Nigam, Neville F. Hacker, Kylie L. Gorringe, Ian G. Campbell, Mark S. Carey
Publikováno v:
npj Precision Oncology, Vol 6, Iss 1, Pp 1-8 (2022)
Abstract Hormone receptor expression is a characteristic of low-grade serous ovarian carcinoma (LGSOC). Studies investigating estrogen receptor (ER) and progesterone receptor (PR) expression levels suggest its prognostic and predictive significance,
Externí odkaz:
https://doaj.org/article/c07926245a9a4565975b9f415dbd3ba0
Autor:
Eun Young Kang, Nicholas JP Wiebe, Christa Aubrey, Cheng‐Han Lee, Michael S Anglesio, Derek Tilley, Prafull Ghatage, Gregg S Nelson, Sandra Lee, Martin Köbel
Publikováno v:
The Journal of Pathology: Clinical Research, Vol 8, Iss 1, Pp 19-32 (2022)
Abstract The World Health Organization endorses molecular subclassification of endometrial endometrioid carcinomas (EECs). Our objectives were to test the sensitivity of tumor morphology in capturing p53 abnormal (p53abn) cases and to model the impac
Externí odkaz:
https://doaj.org/article/5a802f76366a4caa80bc49135d81a275
Autor:
Dylan Dieters-Castator, Paola M. Dantonio, Matt Piaseczny, Guihua Zhang, Jiahui Liu, Miljan Kuljanin, Stephen Sherman, Michael Jewer, Katherine Quesnel, Eun Young Kang, Martin Köbel, Gabrielle M. Siegers, Andrew Leask, David Hess, Gilles Lajoie, Lynne-Marie Postovit
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 4, Pp 375-390 (2021)
The tumor microenvironment (TME) is an important mediator of breast cancer progression. Cancer-associated fibroblasts constitute a major component of the TME and may originate from tissue-associated fibroblasts or infiltrating mesenchymal stromal cel
Externí odkaz:
https://doaj.org/article/12aee79287f34bb1b635b9f1f1242d5c
Autor:
Basile Tessier‐Cloutier, Mackenzie Coatham, Mark Carey, Gregg S Nelson, Sarah Hamilton, Amy Lum, Robert A Soslow, Colin JR Stewart, Lynne M Postovit, Martin Köbel, Cheng‐Han Lee
Publikováno v:
The Journal of Pathology: Clinical Research, Vol 7, Iss 2, Pp 144-153 (2021)
Abstract Dedifferentiated/undifferentiated endometrial carcinoma (DDEC/UEC) is an endometrial cancer characterized by the presence of histologically undifferentiated carcinoma. Genomic inactivation of core switch/sucrose nonfermentable (SWI/SNF) comp
Externí odkaz:
https://doaj.org/article/bf98ac6b77c14b3d908ee324f9f17d79