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of 9
pro vyhledávání: '"Martin, Hessner"'
Autor:
AMINA BEDRAT, SHUANG JIA, MARK ROETHLE, KRISTEN DEW, SUSANNE M. CABRERA, CHIEN-WEI LIN, MARTIN HESSNER
Publikováno v:
Diabetes. 71
Significant phenotypic diversity exists among T1D patients, supporting the existence of distinct disease endotypes (e.g. duration of the post-onset partial remission period) . To broaden our understanding of T1D heterogeneity and its relationship to
Autor:
Parthav Jailwala, Jill Waukau, Sanja Glisic, Srikanta Jana, Sarah Ehlenbach, Martin Hessner, Ramin Alemzadeh, Shigemi Matsuyama, Purushottam Laud, Xujing Wang, Soumitra Ghosh
Publikováno v:
PLoS ONE, Vol 4, Iss 8, p e6527 (2009)
BACKGROUND:Type 1 diabetes (T1D) is a T-cell mediated autoimmune disease targeting the insulin-producing pancreatic beta cells. Naturally occurring FOXP3(+)CD4(+)CD25(high) regulatory T cells (T(regs)) play an important role in dominant tolerance, su
Externí odkaz:
https://doaj.org/article/a2460747afee4eecacf0251596938b86
Autor:
Michael A, Liss, Michael, Schlicht, Andrea, Kahler, Ryan, Fitzgerald, Taylor, Thomassi, Amy, Degueme, Martin, Hessner, Milton W, Datta
Publikováno v:
Cancer genomicsproteomics. 7(5)
A soy-based diet has been associated with a decreased risk of prostate cancer through its anti-androgenic effects. Because the Wnt/beta catenin pathway has been associated with aggressive prostate cancer, we have sought to further evaluate this pathw
Publikováno v:
Cancer genomicsproteomics. 7(3)
The main purified compound from soy protein isolates is genistein, but this purified phytoestrogen fails to recapitulate all the features of the soy-based diet that is associated with lower incidence of prostate cancer.Rat and human prostate cancer c
Publikováno v:
The Journal of Immunology. 188:171.43-171.43
Despite sharing the H2g7 MHC, the closely NOD-related NOR strain remains type 1 diabetes (T1D) resistant due to the presence of protective Idd5.2, Idd9/11, and Idd13 loci. We previously showed that CD4-T cells isolated from the Idd9/11 congenic strai
Autor:
Erica Schmitt, Dipica Haribhai, Jason Williams, Shuang Jia, Praful Aggarwal, Ke Yan, Ulrich Broeckel, Pippa Simpson, Nita Salzman, Martin Hessner, Calvin Williams
Publikováno v:
The Journal of Immunology. 188:179.19-179.19
Induced Treg (iTreg) cells are essential for tolerance. Although in vitro derived iTreg cells can be used therapeutically in preclinical models of autoimmune disease, their stability in vivo and their mechanisms of suppression have not been examined.
Autor:
Rupali Das, Richard Komorowski, Martin Hessner, Hariharan Subramaniam, Daniel J Cua, Claudia Huettner, William R. Drobyski
Publikováno v:
Blood. 114:231-231
Abstract 231 Separation of graft versus leukemia (GVL) and graft versus host (GVH) reactivity has been a longstanding but elusive goal in allogeneic bone marrow transplantation (BMT). The difficulty in dissociating these two responses stems in part f
Publikováno v:
Blood. 112:64-64
The initiation of graft-versus-host disease (GVHD) is dependent upon donor T cell recognition of host alloantigens presented within the context of host antigen presenting cells (APCs). Eventually host APCs are replaced by donor APCs, however the role
Autor:
Schulteis, Ryan D., Dai, Xuezhi, Chu, Haiyan, Edwards, Brandon, Haribhai, Dipica, Williams, Calvin B., Malarkannan, Subramanium, Martin, Hessner J., Anne, Kwitek E., Lernmark, A°ke, Gorski, Jack, Wang, Demin, Weiler, Hartmut
Publikováno v:
Blood; November 2006, Vol. 108 Issue: 11 p921-921, 1p