Alternating L4 loop architecture of the bacterial polysaccharide co-polymerase WzzE

Autor: Benjamin Wiseman, Göran Widmalm, Martin Högbom

Publikováno v: Communications Biology, Vol 6, Iss 1, Pp 1-10 (2023)

Abstract Lipopolysaccharides such as the enterobacterial common antigen are important components of the enterobacterial cell envelope that act as a protective barrier against the environment and are often polymerized by the inner membrane bound Wzy-d

Externí odkaz: https://doaj.org/article/14d2860152484fb4adc21aa78b12d129

Redox-controlled reorganization and flavin strain within the ribonucleotide reductase R2b–NrdI complex monitored by serial femtosecond crystallography

Autor: Juliane John, Oskar Aurelius, Vivek Srinivas, Patricia Saura, In-Sik Kim, Asmit Bhowmick, Philipp S Simon, Medhanjali Dasgupta, Cindy Pham, Sheraz Gul, Kyle D Sutherlin, Pierre Aller, Agata Butryn, Allen M Orville, Mun Hon Cheah, Shigeki Owada, Kensuke Tono, Franklin D Fuller, Alexander Batyuk, Aaron S Brewster, Nicholas K Sauter, Vittal K Yachandra, Junko Yano, Ville RI Kaila, Jan Kern, Hugo Lebrette, Martin Högbom

Publikováno v: eLife, Vol 11 (2022)

Redox reactions are central to biochemistry and are both controlled by and induce protein structural changes. Here, we describe structural rearrangements and crosstalk within the Bacillus cereus ribonucleotide reductase R2b–NrdI complex, a di-metal

Externí odkaz: https://doaj.org/article/621e582ac6f34d829caaf03eb18f2436

Interactions between the Aggregatibacter actinomycetemcomitans secretin HofQ and host cytokines indicate a link between natural competence and interleukin-8 uptake

Autor: Tuuli Ahlstrand, Annamari Torittu, Heli Elovaara, Hannamari Välimaa, Marja T. Pöllänen, Sergo Kasvandik, Martin Högbom, Riikka Ihalin

Publikováno v: Virulence, Vol 9, Iss 1, Pp 1205-1223 (2018)

Naturally competent bacteria acquire DNA from their surroundings to survive in nutrient-poor environments and incorporate DNA into their genomes as new genes for improved survival. The secretin HofQ from the oral pathogen Aggregatibacter actinomycete

Externí odkaz: https://doaj.org/article/7059331c049f4841a0b578684e6bc7af

Functional design of bacterial superoxide:quinone oxidoreductase

Autor: Abbas Abou-Hamdan, Roman Mahler, Philipp Grossenbacher, Olivier Biner, Dan Sjöstrand, Martin Lochner, Martin Högbom, Christoph von Ballmoos

Publikováno v: Abou Hamdan, Abbas; Mahler, Roman; Grossenbacher, Philipp; Biner, Olivier; Sjöstrand, Dan; Lochner, Martin; Högbom, Martin; von Ballmoos, Christoph (2022). Functional design of bacterial superoxide:quinone oxidoreductase. Biochimica et biophysica acta. Bioenergetics, 1863(7), p. 148583. Elsevier 10.1016/j.bbabio.2022.148583

The superoxide anion - molecular oxygen reduced by a single electron - is produced in large amounts by enzymatic and adventitious reactions and can perform a range of cellular functions, including bacterial warfare and iron uptake, signalling and hos

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f45e63f8c88e8af7797b3f817673776c
https://boris.unibe.ch/170499/9/1-s2.0-S0005272822000524-main.pdf

Author response: Redox-controlled reorganization and flavin strain within the ribonucleotide reductase R2b–NrdI complex monitored by serial femtosecond crystallography

Autor: Juliane John, Oskar Aurelius, Vivek Srinivas, Patricia Saura, In-Sik Kim, Asmit Bhowmick, Philipp S Simon, Medhanjali Dasgupta, Cindy Pham, Sheraz Gul, Kyle D Sutherlin, Pierre Aller, Agata Butryn, Allen M Orville, Mun Hon Cheah, Shigeki Owada, Kensuke Tono, Franklin D Fuller, Alexander Batyuk, Aaron S Brewster, Nicholas K Sauter, Vittal K Yachandra, Junko Yano, Ville RI Kaila, Jan Kern, Hugo Lebrette, Martin Högbom

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c65863ea9268f4b72af1144aadca99d5
https://doi.org/10.7554/elife.79226.sa2