Zobrazeno 1 - 10
of 569
pro vyhledávání: '"Martin, Canis"'
Autor:
Marcel Mayer, Julia Esser, Sarah Victoria Walker, Sami Shabli, Axel Lechner, Martin Canis, Jens Peter Klussmann, Lisa Nachtsheim, Philipp Wolber
Publikováno v:
Head & Face Medicine, Vol 20, Iss 1, Pp 1-10 (2024)
Abstract Background A parotid abscess (PA) is a complication of an acute bacterial parotitis with a potentially life-threatening course. To date, data on the diagnosis and therapy of PA is sparse and mostly consists of case reports or case series. Th
Externí odkaz:
https://doaj.org/article/1c86bec2abaa41f58f5728aa4b765e36
Autor:
Benedek Dankó, Julia Hess, Kristian Unger, Daniel Samaga, Christoph Walz, Axel Walch, Na Sun, Philipp Baumeister, Peter Y. F. Zeng, Franziska Walter, Sebastian Marschner, Richard Späth, Olivier Gires, Timm Herkommer, Ramin Dazeh, Thaina Matos, Lisa Kreutzer, Johann Matschke, Katharina Eul, Frederick Klauschen, Ulrike Pflugradt, Martin Canis, Ute Ganswindt, Joe S. Mymryk, Barbara Wollenberg, Anthony C. Nichols, Claus Belka, Horst Zitzelsberger, Kirsten Lauber, Martin Selmansberger
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-20 (2024)
Abstract Head and Neck Squamous Cell Carcinoma (HNSCC) is a heterogeneous malignancy that remains a significant challenge in clinical management due to frequent treatment failures and pronounced therapy resistance. While metabolic dysregulation appea
Externí odkaz:
https://doaj.org/article/478152ef0db84845b323352406d212bd
Autor:
Enxian Shi, Zhengquan Wu, Birnur Sinem Karaoglan, Sabina Schwenk-Zieger, Gisela Kranz, Nilofer Abdul Razak, Christoph A. Reichel, Martin Canis, Philipp Baumeister, Reinhard Zeidler, Olivier Gires
Publikováno v:
Journal of Biomedical Science, Vol 30, Iss 1, Pp 1-20 (2023)
Abstract Background Epithelial-to-mesenchymal transition (EMT) of malignant cells is a driving force of disease progression in human papillomavirus-negative (HPV-negative) head and neck squamous cell carcinomas (HNSCC). Sustained hyper-activation of
Externí odkaz:
https://doaj.org/article/a19c6c69db73497296f9698ab827c111
Autor:
Magdalena Stocker, Alexandra Blancke Soares, Gregor Liebsch, Robert J. Meier, Martin Canis, Olivier Gires, Frank Haubner
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
IntroductionHead and neck squamous cell carcinoma (HNSCC) patients suffer from frequent local recurrences that negatively impact on prognosis. Hence, distinguishing tumor and normal tissue is of clinical importance as it may improve the detection of
Externí odkaz:
https://doaj.org/article/def4c067729e4e8abf3f24c6288cdc54
Autor:
Henrik Schinke, Enxian Shi, Zhongyang Lin, Tanja Quadt, Gisela Kranz, Jiefu Zhou, Hongxia Wang, Julia Hess, Steffen Heuer, Claus Belka, Horst Zitzelsberger, Udo Schumacher, Sandra Genduso, Kristoffer Riecken, Yujing Gao, Zhengquan Wu, Christoph A. Reichel, Christoph Walz, Martin Canis, Kristian Unger, Philipp Baumeister, Min Pan, Olivier Gires
Publikováno v:
Molecular Cancer, Vol 21, Iss 1, Pp 1-25 (2022)
Abstract Background Epidermal growth factor receptor (EGFR) is both a driver oncogene and a therapeutic target in advanced head and neck squamous cell carcinoma (HNSCC). However, response to EGFR treatment is inconsistent and lacks markers for treatm
Externí odkaz:
https://doaj.org/article/95531d59b79a463e83a7c5658acca70f
Autor:
Mattis Bertlich, Nina Zeller, Saskia Freytag, Jennifer L. Spiegel, Bernhard G. Weiss, Martin Canis, Frank Haubner, Friedrich Ihler
Publikováno v:
BMC Surgery, Vol 22, Iss 1, Pp 1-10 (2022)
Abstract Background Selective neck dissection (SND) is the surgical treatment of choice in squamous cell carcinoma of the head and neck (HNSCC) with suspected or manifest metastases in the cervical lymph nodes. For SND to be successful, treated lymph
Externí odkaz:
https://doaj.org/article/8ada1906853043cfbd1d45fa6395dbda
Autor:
Henrik Schinke, Min Pan, Merve Akyol, Jiefu Zhou, Enxian Shi, Gisela Kranz, Darko Libl, Tanja Quadt, Florian Simon, Martin Canis, Philipp Baumeister, Olivier Gires
Publikováno v:
Molecular Oncology, Vol 16, Iss 2, Pp 347-367 (2022)
Partial epithelial‐to‐mesenchymal transition (pEMT) contributes to cellular heterogeneity that is associated with nodal metastases and unfavorable clinical parameters in head and neck squamous cell carcinomas (HNSCCs). We developed a single‐cel
Externí odkaz:
https://doaj.org/article/fc274dc569f8458e8023a0c68c5014e2
Autor:
Bernd Uhl, Florian Haring, Julia Slotta-Huspenina, Joshua Luft, Vera Schneewind, Jonas Hildinger, Zhengquan Wu, Katja Steiger, Bojan Smiljanov, Aarif M. N. Batcha, Oliver T. Keppler, Johannes C. Hellmuth, Tobias Lahmer, Konrad Stock, Bernhard G. Weiss, Martin Canis, Konstantin Stark, Thomas Bromberger, Markus Moser, Christian Schulz, Wilko Weichert, Gabriele Zuchtriegel, Christoph A. Reichel
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Microvascular immunothrombotic dysregulation is a critical process in the pathogenesis of severe systemic inflammatory diseases. The mechanisms controlling immunothrombosis in inflamed microvessels, however, remain poorly understood. Here, we report
Externí odkaz:
https://doaj.org/article/ade407ee878a42518dbdd312efef54f7
Autor:
Jiefu Zhou, Sabina Schwenk-Zieger, Gisela Kranz, Christoph Walz, Frederik Klauschen, Sharduli Dhawan, Martin Canis, Olivier Gires, Frank Haubner, Philipp Baumeister, Vera Kohlbauer
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
IntroductionHead and neck squamous cell carcinomas (HNSCC) are characterized by strong cellular and molecular heterogeneity and treatment resistance entailing poor survival. Besides cell-intrinsic properties, carcinoma cells receive important cues fr
Externí odkaz:
https://doaj.org/article/ca1fb1c4d8af49d0bd27054ec938fdf6
Autor:
Kariem Sharaf, Axel Lechner, Stefan P. Haider, Robert Wiebringhaus, Christoph Walz, Gisela Kranz, Martin Canis, Frank Haubner, Olivier Gires, Philipp Baumeister
Publikováno v:
Current Oncology, Vol 28, Iss 4, Pp 2763-2774 (2021)
Cancer stem cells (CSCs) are accountable for the progress of head and neck squamous cell carcinoma (HNSCC). This exploratory study evaluated the expression of molecular CSC markers in different tissues of HNSCC patients. Tissue specimens of primary t
Externí odkaz:
https://doaj.org/article/856ba980079f4b48a56d8fc599560588