Zobrazeno 1 - 10
of 138
pro vyhledávání: '"Martin, Baron"'
Autor:
Elzava Yuslimatin Mujizah, Satoshi Kuwana, Kenjiroo Matsumoto, Takuma Gushiken, Naoki Aoyama, Hiroyuki O. Ishikawa, Takeshi Sasamura, Daiki Umetsu, Mikiko Inaki, Tomoko Yamakawa, Martin Baron, Kenji Matsuno
Publikováno v:
Biomolecules, Vol 14, Iss 9, p 1062 (2024)
The role of Drosophila numb in regulating Notch signaling and neurogenesis has been extensively studied, with a particular focus on its effects on the peripheral nervous system (PNS). Previous studies based on a single loss-of-function allele of numb
Externí odkaz:
https://doaj.org/article/2572c86223e642aa886aeaf6fec28dac
Autor:
Marian B. Wilkin, Rory Whiteford, Tanveer Akbar, Samira Hosseini-Alghaderi, Raluca Revici, Ann-Marie Carbery, Martin Baron
Publikováno v:
Biomolecules, Vol 14, Iss 5, p 522 (2024)
Suppressor of deltex (Su(dx)) is a Drosophila melanogaster member of the NEDD4 family of the HECT domain E3 ubiquitin ligases. Su(dx) acts as a regulator of Notch endocytic trafficking, promoting Notch lysosomal degradation and the down-regulation of
Externí odkaz:
https://doaj.org/article/fa4d2b8d065640fb88ac9efb10175abb
Publikováno v:
BMC Biology, Vol 20, Iss 1, Pp 1-25 (2022)
Abstract Background Ubiquitylation of the ligands and the receptor plays an important part in the regulation of the activity of the evolutionary conserved Notch signalling pathway. However, its function for activation of Notch is not completely under
Externí odkaz:
https://doaj.org/article/16d7aa12301245c9a8d8bb723840e7be
Autor:
Ahmet Acar, Ana Hidalgo-Sastre, Michael K. Leverentz, Christopher G. Mills, Simon Woodcock, Martin Baron, Giovanna M. Collu, Keith Brennan
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Notch and Wnt are two essential signalling pathways that help to shape animals during development and to sustain adult tissue homeostasis. Although they are often active at the same time within a tissue, they typically have opposing effects
Externí odkaz:
https://doaj.org/article/3b960ed61ced47819d25ef2b2656f61c
Publikováno v:
Feminist Teacher, 2018 Jan 01. 28(2-3), 70-78.
Externí odkaz:
https://www.jstor.org/stable/10.5406/femteacher.28.2-3.0070
Publikováno v:
Biomolecules, Vol 12, Iss 2, p 224 (2022)
Notch is a developmental receptor, conserved in the evolution of the metazoa, which regulates cell fate proliferation and survival in numerous developmental contexts, and also regulates tissue renewal and repair in adult organisms. Notch is activated
Externí odkaz:
https://doaj.org/article/6dcf6636277e4a118200af5863cc597b
Publikováno v:
Biomolecules, Vol 10, Iss 3, p 485 (2020)
Notch3 is one of four mammalian Notch proteins, which act as signalling receptors to control cell fate in many developmental and adult tissue contexts. Notch signalling continues to be important in the adult organism for tissue maintenance and renewa
Externí odkaz:
https://doaj.org/article/1f285c1a96064f6194572b106324cec4
Publikováno v:
Applied Radiation and Isotopes. 198:110842
Autor:
Hideyuki Shimizu, Marian B. Wilkin, Simon A. Woodcock, Alessandro Bonfini, Yvonne Hung, Sabine Mazaleyrat, Martin Baron
Publikováno v:
Open Biology, Vol 7, Iss 4 (2017)
The developmental signalling protein Notch can be proteolytically activated following ligand-interaction at the cell surface, or can be activated independently of its ligands, following Deltex (Dx)-induced Notch endocytosis and trafficking to the lys
Externí odkaz:
https://doaj.org/article/b858427a73ae40a69ce1a3b2d8cefd6e
Publikováno v:
Revici, R, Hosseini Alghaderi, S S, Haslam, F, Whiteford, R & Baron, M 2022, ' E3 Ubiquitin Ligase Regulators of Notch Receptor Endocytosis: From Flies to Humans ', Biomolecules, vol. 12, no. 2 . https://doi.org/https://www.mdpi.com/2218-273X/12/2/224
Revici, R, Hosseini Alghaderi, S S, Haslam, F, Whiteford, R & Baron, M 2022, ' E3 Ubiquitin Ligase Regulators of Notch Receptor Endocytosis: From Flies to Humans ', Biomolecules, vol. 12, no. 2, 224 . https://doi.org/10.3390/biom12020224, https://doi.org/https://www.mdpi.com/2218-273X/12/2/224
Revici, R, Hosseini Alghaderi, S S, Haslam, F, Whiteford, R & Baron, M 2022, ' E3 Ubiquitin Ligase Regulators of Notch Receptor Endocytosis: From Flies to Humans ', Biomolecules, vol. 12, no. 2, 224 . https://doi.org/10.3390/biom12020224, https://doi.org/https://www.mdpi.com/2218-273X/12/2/224
Notch is a developmental receptor, conserved in the evolution of the metazoa, which regulates cell fate proliferation and survival in numerous developmental contexts, and also regulates tissue renewal and repair in adult organisms. Notch is activated