Limited Role of the Apparent Diffusion Coefficient (ADC) for Tumor Grade and Overall Survival in Resectable Pancreatic Ductal Adenocarcinoma

Autor: Deniece M. Riviere, Marnix C. Maas, Lodewijk A. A. Brosens, Martijn W. J. Stommel, Cornelis J. H. M. van Laarhoven, John J. Hermans

Publikováno v: Diagnostics, Vol 14, Iss 6, p 573 (2024)

This study evaluated the relationship between apparent diffusion coefficient (ADC) values in pancreatic ductal adenocarcinoma (PDAC) and tumor grades based on WHO, Adsay, and Kalimuthu classifications, using whole-mount pancreatectomy specimens. If g

Externí odkaz: https://doaj.org/article/a5f4661b21b24cd7a6b32f662b9b9599

A proof of concept using the Ussing chamber methodology to study pediatric intestinal drug transport and age‐dependent differences in absorption

Autor: Eva J. Streekstra, Márton Kiss, Jeroen van denHeuvel, Johan Nicolaï, Petra van denBroek, Sanne M. B. I. Botden, Martijn W. J. Stommel, Lara vanRijssel, Anna‐Lena Ungell, Evita van deSteeg, Frans G. M. Russel, Saskia N. deWildt

Publikováno v: Clinical and Translational Science, Vol 15, Iss 10, Pp 2392-2402 (2022)

Abstract Little is known about the impact of age on the processes governing human intestinal drug absorption. The Ussing chamber is a system to study drug transport across tissue barriers, but it has not been used to study drug absorption processes i

Externí odkaz: https://doaj.org/article/19dc0c00bdde4a0c98ee0dc9ad49aa34

Fibroblast Activation Protein-Targeting Minibody-IRDye700DX for Ablation of the Cancer-Associated Fibroblast with Photodynamic Therapy

Autor: Esther M. M. Smeets, Daphne N. Dorst, Gerben M. Franssen, Merijn S. van Essen, Cathelijne Frielink, Martijn W. J. Stommel, Marija Trajkovic-Arsic, Phyllis F. Cheung, Jens T. Siveke, Ian Wilson, Alessandro Mascioni, Erik H. J. G. Aarntzen, Sanne A. M. van Lith

Publikováno v: Cells, Vol 12, Iss 10, p 1420 (2023)

Fibroblast activation protein (FAP), expressed on cancer-associated fibroblasts, is a target for diagnosis and therapy in multiple tumour types. Strategies to systemically deplete FAP-expressing cells show efficacy; however, these induce toxicities,

Externí odkaz: https://doaj.org/article/6aff23dd68ac4fd7aa278e29c1b723ca

Bihormonal Artificial Pancreas With Closed-Loop Glucose Control vs Current Diabetes Care After Total Pancreatectomy: A Randomized Clinical Trial

Autor: Charlotte L, van Veldhuisen, Anouk E J, Latenstein, Helga, Blauw, Lyan B, Vlaskamp, Michel, Klaassen, Daan J, Lips, Bert A, Bonsing, Erwin, van der Harst, Martijn W J, Stommel, Marco J, Bruno, Hjalmar C, van Santvoort, Casper H J, van Eijck, Susan, van Dieren, Olivier R, Busch, Marc G, Besselink, J Hans, DeVries, Ralph, de Vries

Publikováno v: JAMA surgery. 157(10)

Glucose control in patients after total pancreatectomy is problematic because of the complete absence of α- and β-cells, leading to impaired quality of life. A novel, bihormonal artificial pancreas (BIHAP), using both insulin and glucagon, may impr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7eec82f5b6c697daed8a63fdf8fd7502
https://pubmed.ncbi.nlm.nih.gov/36069829

Impact of Complications After Pancreatoduodenectomy on Mortality, Organ Failure, Hospital Stay, and Readmission: Analysis of a Nationwide Audit

Autor: Bert A. Bonsing, Marc G. Besselink, Geert Kazemier, Olivier R. Busch, F. Jasmijn Smits, Ignace H J T de Hingh, Sebastiaan Festen, Mark Meerdink, Erwin van der Harst, Misha Luyer, Martijn W J Stommel, Mike Liem, Marion van der Kolk, I. Quintus Molenaar, Casper H.J. van Eijck, Lois A Daamen, Ronald M. van Dam, Maaike E Verweij, C. Henri van Werkhoven, Jennifer M.J. Schreinemakers, Babs M Zonderhuis, Daphne Roos, F. Wit, Hjalmar C. van Santvoort, Bas Groot Koerkamp, Lucas Goense, Vincent E de Meijer, Vincent B. Nieuwenhuijs, Joost M. Klaase, J. Sven D. Mieog

Publikováno v: Annals of surgery, 275(1), E222-E228. Lippincott Williams and Wilkins
Annals of Surgery, 275(1), E222-E228. LIPPINCOTT WILLIAMS & WILKINS
Annals of Surgery, 275(1), E222-E228. Lippincott Williams and Wilkins
Annals of Surgery, 275, 1, pp. e222-e228
Jasmijn Smits, F, Verweij, M E, Daamen, L A, Henri van Werkhoven, C, Goense, L, Besselink, M G, Bonsing, B A, Busch, O R, van Dam, R M, van Eijck, C H J, Festen, S, Koerkamp, B G, van der Harst, E, de Hingh, I H, Kazemier, G, Klaase, J M, van der Kolk, M, Liem, M, Luyer, M D P, Meerdink, M, Sven D. Mieog, J, Nieuwenhuijs, V B, Roos, D, Schreinemakers, J M, Stommel, M W, Wit, F, Zonderhuis, B M, de Meijer, V E, van Santvoort, H C & Quintus Molenaar, I 2022, ' Impact of Complications after Pancreatoduodenectomy on Mortality, Organ Failure, Hospital Stay, and Readmission Analysis of a Nationwide Audit ', Annals of Surgery, vol. 275, no. 1, pp. E222-E228 . https://doi.org/10.1097/SLA.0000000000003835
Annals of Surgery, 275, e222-e228
Annals of Surgery, 275(1), E222-E228. Lippincott Williams & Wilkins

Contains fulltext : 251531.pdf (Publisher’s version ) (Closed access) OBJECTIVE: To quantify the impact of individual complications on mortality, organ failure, hospital stay, and readmission after pancreatoduodenectomy. SUMMARY OF BACKGROUND DATA:

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fed5495f8e132144713370710c4fa8d5
https://hdl.handle.net/2066/251531