Mild dyserythropoiesis and β-like globin gene expression imbalance due to the loss of histone chaperone ASF1B

Autor: Petros Papadopoulos, Athanassia Kafasi, Iris M. De Cuyper, Vilma Barroca, Daniel Lewandowski, Zahra Kadri, Martijn Veldthuis, Jeffrey Berghuis, Nynke Gillemans, Celina María Benavente Cuesta, Frank G. Grosveld, Rob van Zwieten, Sjaak Philipsen, Muriel Vernet, Laura Gutiérrez, George P. Patrinos

Publikováno v: Human Genomics, Vol 14, Iss 1, Pp 1-12 (2020)

Abstract The expression of the human β-like globin genes follows a well-orchestrated developmental pattern, undergoing two essential switches, the first one during the first weeks of gestation (ε to γ), and the second one during the perinatal peri

Externí odkaz: https://doaj.org/article/ebde74cd3e4042dc96bb58a33041796f

Voxelotor Treatment Leads to Improved Viability of Sickle Erythrocytes and Altered Neutrophil Phenotype

Autor: Kadère Konté, Aafke E. Gaartman, Boukje M. Beuger, Martijn Veldthuis, Rob van Zwieten, Robin Van Bruggen, Bart J. Biemond, Erfan Nur

Publikováno v: Blood. 140:11114-11115

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ed8c34cfda28021d671156f9291d9720
https://doi.org/10.1182/blood-2022-170527

Hemolysis in the spleen drives erythrocyte turnover

Autor: W F J van IJcken, Thomas R. L. Klei, Sietse Q. Nagelkerke, Martijn Veldthuis, Benjamin Nota, R van Zwieten, J Dalimot, Frederik P. J. Mul, F P J van Alphen, T Rademakers, Edwin Oole, Alexander B. Meijer, Mark Hoogenboezem, Taco W. Kuijpers, Søren K. Moestrup, Pia Svendsen, R. van Bruggen

Publikováno v: Klei, T R L, Dalimot, J, Nota, B, Veldthuis, M, Mul, F P J, Rademakers, T, Hoogenboezem, M, Nagelkerke, S Q, van IJcken, W F J, Oole, E, Svendsen, P, Moestrup, S K, van Alphen, F P J, Meijer, A B, Kuijpers, T W, van Zwieten, R & van Bruggen, R 2020, ' Hemolysis in the spleen drives erythrocyte turnover ', Blood, vol. 136, no. 14, pp. 1579-1589 . https://doi.org/10.1182/blood.2020005351
Blood, 136(14), 1579-1589. The American Society of Hematology
Blood, 136(14), 1579. Amer Soc Hematology
Blood, 136(14), 1579-1589. American Society of Hematology

Red pulp macrophages (RPMs) of the spleen mediate turnover of billions of senescent erythrocytes per day. However, the molecular mechanisms involved in sequestration of senescent erythrocytes, their recognition, and their subsequent degradation by RP

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f35ab5a9fde47f37d72acf4e0a11838b
https://pure.au.dk/portal/da/publications/hemolysis-in-the-spleen-drives-erythrocyte-turnover(507ae87c-abcf-472f-8db3-ed1373f52970).html

Mild dyserythropoiesis and b-like globin gene expression imbalance due to the loss of histone chaperone ASF1B

Autor: Petros Papadopoulos, Athanassia Kafasi, Iris de Cuyper, Vilma Barroca, Daniel Lewandowski, Zahra Kadri, Martijn Veldthuis, Jeffrey Berghuis, Nynke Gillemans, Celina María Benavente Cuesta, Frank Grosveld, Rob van Zwieten, Sjaak Philipsen, Muriel Vernet, Laura Gutiérrez, George Patrinos

The expression of the human b-like globin genes follows a well-orchestrated developmental pattern, undergoing two essential switches, the first one during the first weeks of gestation (e to g), and the second one during the perinatal period (g to b).

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93291d4e923e149169b39159663f472f
https://doi.org/10.21203/rs.3.rs-44936/v1

Mild dyserythropoiesis and β-like globin gene expression imbalance due to the loss of histone chaperone ASF1B

Autor: Athanassia Kafasi, Petros Papadopoulos, Daniel Lewandowski, Celina Benavente Cuesta, Martijn Veldthuis, Muriel Vernet, Laura Gutierrez, Vilma Barroca, Rob van Zwieten, Frank Grosveld, George P. Patrinos, Zahra Kadri, Iris M. De Cuyper, Sjaak Philipsen, Jeffrey Berghuis, Nynke Gillemans

Publikováno v: RUO. Repositorio Institucional de la Universidad de Oviedo
Universidad de las Islas Baleares
Human Genomics, Vol 14, Iss 1, Pp 1-12 (2020)
Human Genomics, 14(1):39. BioMed Central Ltd.
Human Genomics
Human genomics, 14(1):39. Henry Stewart Publications
RUO: Repositorio Institucional de la Universidad de Oviedo
Universidad de Oviedo (UNIOVI)

The expression of the human β-like globin genes follows a well-orchestrated developmental pattern, undergoing two essential switches, the first one during the first weeks of gestation (ε to γ), and the second one during the perinatal period (γ to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::920c4af772662496d3aee8316d60576c
http://hdl.handle.net/10651/57181