Zobrazeno 1 - 10
of 641
pro vyhledávání: '"Martijn Van Griensven"'
Autor:
Wouter A. J. Vints, Oron Levin, Martijn van Griensven, Johan W. S. Vlaeyen, Nerijus Masiulis, Jeanine Verbunt, Charlotte C. M. van Laake-Geelen
Publikováno v:
BMC Neurology, Vol 24, Iss 1, Pp 1-12 (2024)
Abstract Introduction Individuals with spinal cord injury (SCI) can experience accelerated cognitive aging. Myokines (factors released from muscle cells during contractions), such as brain-derived neurotrophic factor (BDNF), are thought to have benef
Externí odkaz:
https://doaj.org/article/8d26901b91274290b864b17ea2280ee6
Autor:
Yang Li, Klemens Horst, Johannes Greven, Ümit Mert, Ludmila Lupu, Annette Palmer, Lena Doerfer, Qun Zhao, Xing Zhang, Rebecca Halbgebauer, Anita Ignatius, Ingo Marzi, Martijn van Griensven, Elizabeth Balmayor, Frank Hildebrand, Tom Eirik Mollnes, Markus Huber-Lang
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundPolytrauma and hemorrhagic shock can lead to direct and indirect liver damage involving intricate pathophysiologic mechanisms. While hepatic function has been frequently highlighted, there is minimal research on how the receptor activator o
Externí odkaz:
https://doaj.org/article/0dd4a07f570e42239e70c8a2eeb84d2e
Autor:
Rald V. M. Groven, Christel Kuik, Johannes Greven, Ümit Mert, Freek G. Bouwman, Martijn Poeze, Taco J. Blokhuis, Markus Huber-Lang, Frank Hildebrand, Berta Cillero-Pastor, Martijn van Griensven
Publikováno v:
Bone & Joint Research, Vol 13, Iss 5, Pp 214-225 (2024)
Aims: The aim of this study was to determine the fracture haematoma (fxH) proteome after multiple trauma using label-free proteomics, comparing two different fracture treatment strategies. Methods: A porcine multiple trauma model was used in which tw
Externí odkaz:
https://doaj.org/article/573a6f6a87ed43d9be6fe17da2e0373b
Autor:
Fangzhou Lu, Rald V. M. Groven, Martijn van Griensven, Martijn Poeze, Jan A. P. Geurts, Shan Shan Qiu, Taco J. Blokhuis
Publikováno v:
Journal of Orthopaedics and Traumatology, Vol 25, Iss 1, Pp 1-9 (2024)
Abstract Background Treating tibial non-unions efficiently presents a challenge for orthopaedic trauma surgeons. The established gold standard involves implanting autologous bone graft with adequate fixation, but the addition of biologicals according
Externí odkaz:
https://doaj.org/article/0f7f451bd23e49fe86f01829ebbbdf03
Autor:
Nan Zhou, Rald V. M. Groven, Klemens Horst, Ümit Mert, Johannes Greven, Tom Eirik Mollnes, Markus Huber-Lang, Martijn van Griensven, Frank Hildebrand, Elizabeth R. Balmayor
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundRespiratory failure can be a severe complication after polytrauma. Extensive systemic inflammation due to surgical interventions, as well as exacerbated post-traumatic immune responses influence the occurrence and progression of respiratory
Externí odkaz:
https://doaj.org/article/7684696c74d540418c2efae014825520
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 12 (2024)
Tendons are a frequent site of injury, which greatly impairs the movement and locomotion of patients. Regrettably, injuries at the tendon frequently require surgical intervention, which leads to a long path to recovery. Moreover, the healing of tendo
Externí odkaz:
https://doaj.org/article/ddba77aadc5848a3b7e4bf259a473bdb
Autor:
Eduardo Gushiken, Milagros Quintana, Luz Agueda Perez, Patricia Herrera-Velit, Elizabeth R. Balmayor, Martijn van Griensven, Jose R. Espinoza
Publikováno v:
Electronic Journal of Biotechnology, Vol 66, Iss , Pp 60-66 (2023)
Background: Human adipose tissue-derived stem cells (ASCs) are widely used in regenerative medicine and tissue engineering. Magnetic-activated cell sorting (MACS) with monoclonal antibodies (mAbs) that bind surface markers of stem cells such as CD105
Externí odkaz:
https://doaj.org/article/042dbd316c8a43bd83552782789f96e7
Autor:
Zeynep Karagöz, Fiona R. Passanha, Lars Robeerst, Martijn van Griensven, Vanessa L. S. LaPointe, Aurélie Carlier
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Various cell surface receptors play an important role in the differentiation and self-renewal of human mesenchymal stem cells (hMSCs). One example of such receptors are the cadherins, which maintain cell–cell adhesion and mechanically coup
Externí odkaz:
https://doaj.org/article/597582b8affb45fe84423e00bd34b8a1
Autor:
Claudia Del Toro Runzer, Shivesh Anand, Carlos Mota, Lorenzo Moroni, Christian Plank, Martijn van Griensven, Elizabeth R. Balmayor
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 32, Iss , Pp 960-979 (2023)
Nucleic acids have clear clinical potential for gene therapy. Plasmid DNA (pDNA) was the first nucleic acid to be pursued as a therapeutic molecule. Recently, mRNA came into play as it offers improved safety and affordability. In this study, we inves
Externí odkaz:
https://doaj.org/article/1ddd12fb6e494d58b9485ed19a79a69e
Autor:
Bingduo Wang, Aliona Wöhler, Johannes Greven, Rebekka J. S. Salzmann, Cindy M. Keller, Tobias Tertel, Qun Zhao, Ümit Mert, Klemens Horst, Ludmila Lupu, Markus Huber-Lang, Martijn van Griensven, Tom Erik Mollnes, Sebastian Schaaf, Robert Schwab, Christian P. Strassburg, Ingo G. H. Schmidt-Wolf, Bernd Giebel, Frank Hildebrand, Veronika Lukacs-Kornek, Arnulf G. Willms, Miroslaw T. Kornek
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundDespite major advances in medicine, blood-borne biomarkers are urgently needed to support decision-making, including polytrauma. Here, we assessed serum-derived extracellular vesicles (EVs) as potential markers of decision-making in polytra
Externí odkaz:
https://doaj.org/article/3b8ca466e5ec44dabab96e095d62f58f