Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Martijn Risseeuw"'
Autor:
Aurélie Crabbé, Lisa Ostyn, Sorien Staelens, Charlotte Rigauts, Martijn Risseeuw, Maarten Dhaenens, Simon Daled, Heleen Van Acker, Dieter Deforce, Serge Van Calenbergh, Tom Coenye
Publikováno v:
PLoS Pathogens, Vol 15, Iss 4, p e1007697 (2019)
Antibiotic susceptibility of bacterial pathogens is typically evaluated using in vitro assays that do not consider the complex host microenvironment. This may help explaining a significant discrepancy between antibiotic efficacy in vitro and in vivo,
Externí odkaz:
https://doaj.org/article/2706a68c47b6435aaafd17978aab5542
Autor:
Charlotte Courtens, Frits van Charante, Thibaut Quennesson, Martijn Risseeuw, Paul Cos, Guy Caljon, Tom Coenye, Serge Van Calenbergh
Publikováno v:
European journal of medicinal chemistry
Fosmidomycin is a natural antibiotic with potent IspC (DXR, 1-deoxy-D-xylulose-5-phosphate reductoisomerase) inhibitory activity. This enzyme catalyzes the first committed step of the non-mevalonate isoprenoid biosynthesis pathway, which is essential
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::633f1ce20b064524a78ed0f1488520c7
https://pubmed.ncbi.nlm.nih.gov/36399924
https://pubmed.ncbi.nlm.nih.gov/36399924
Autor:
Muhammad Rishfi, Simon Krols, Fien Martens, Sarah-Lee Bekaert, Ellen Sanders, Aline Eggermont, Fanny De Vloed, Joshua Robert Goulding, Martijn Risseeuw, Jan Molenaar, Bram De Wilde, Serge Van Calenbergh, Kaat Durinck
Publikováno v:
European Journal of Medicinal Chemistry. 247:115033
Aurora kinase A (AURKA) is a well-established target in neuroblastoma (NB) due to its catalytic functions during mitosis and due to stabilisation of the key oncoprotein MYCN. We report a small structure-activity relationship (SAR) study of MK-5108-de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9aedaeb78a0262cf59205bdd691faefe
https://doi.org/10.1016/j.ejmech.2022.115033
https://doi.org/10.1016/j.ejmech.2022.115033