Výsledky vyhledávání - "Martijn Pieffers"

Large, Tissue-regulated Domain Diversity of Heparan Sulfates Demonstrated by Phage Display Antibodies

Autor: Martijn Pieffers, Guido J. Jenniskens, Maurice Petitou, Michel A.B.A. Dennissen, Elly M. M. Versteeg, Toin H. van Kuppevelt, Jacques H. Veerkamp

Publikováno v: Journal of Biological Chemistry, 277, 10982-6
Journal of Biological Chemistry, 277, 13, pp. 10982-6

Contains fulltext : 123006.pdf (Publisher’s version ) (Open Access) Heparan sulfates (HS) are long, linear polysaccharides with a high degree of variability. They bind to a vast number of proteins such as growth factors and cytokines, and these int

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eddb4e16cccc39ac7bba2832b62a77b8
https://doi.org/10.1074/jbc.m104852200

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Characterization of recombinant human autoantibody fragments directed toward the autoantigenic U1-70K protein

Autor: Frank H J van den Hoogen, Jos M.H. Raats, Walther J. van Venrooij, Martijn Pieffers, W.G.J. Degen, Elisabet Welin-Henriksson

Publikováno v: European Journal of Immunology. 30:3029-3038

The U1-70K protein is specifically bound to stemloop I of the U1 small nuclear RNA contained in the U1 small nuclear ribonucleoprotein complex (U1 snRNP), which is involved in the splicing of pre-mRNA. All components of the U1 snRNP complex, includin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ce95761347dc5cc1b4ad3dce0e9eea84
https://doi.org/10.1002/1521-4141(200010)30:10<3029::aid-immu3029>3.0.co

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The Importance of the Light Chain for the Epitope Specificity of Human Anti-U1 Small Nuclear RNA Autoantibodies Present in Systemic Lupus Erythematosus Patients

Autor: René M. A. Hoet, Martijn Pieffers, Maurice H. W. Stassen, Jos Raats, Ruud de Wildt, Ger J. M. Pruijn, Frank van den Hoogen, Walther J. van Venrooij

Publikováno v: The Journal of Immunology. 163:3304-3312

Abs to U1 RNA are frequently found in patients suffering from systemic lupus erythematosus overlap syndromes and Ab titers correlate with disease activity. We describe the isolation of the first human anti-U1 RNA autoantibodies from a combinatorial I

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4e5f4a3031fb63a40c2527168fa01608
https://doi.org/10.4049/jimmunol.163.6.3304

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