Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Martijn L T M Müller"'
Autor:
Jamie L. Adams, Tairmae Kangarloo, Yishu Gong, Vahe Khachadourian, Brian Tracey, Dmitri Volfson, Robert D. Latzman, Joshua Cosman, Jeremy Edgerton, David Anderson, Allen Best, Melissa A. Kostrzebski, Peggy Auinger, Peter Wilmot, Yvonne Pohlson, Stella Jensen-Roberts, Martijn L. T. M. Müller, Diane Stephenson, E. Ray Dorsey, the Parkinson Study Group Watch-PD Study Investigators and Collaborators
Publikováno v:
npj Parkinson's Disease, Vol 10, Iss 1, Pp 1-11 (2024)
Abstract Digital measures may provide objective, sensitive, real-world measures of disease progression in Parkinson’s disease (PD). However, multicenter longitudinal assessments of such measures are few. We recently demonstrated that baseline asses
Externí odkaz:
https://doaj.org/article/7b304f263c954a19b734d9277ee6190c
Publikováno v:
Frontiers in Systems Biology, Vol 4 (2024)
A rich pipeline of therapeutic candidates is advancing for Parkinson’s disease, many of which are targeting the underlying pathophysiology of disease. Emerging evidence grounded in novel genetics and biomarker discoveries is illuminating the true p
Externí odkaz:
https://doaj.org/article/f28f045c4f2845ea9ef9c8eca3076802
Autor:
Elena S. Izmailova, R. Paul Maguire, Timothy J. McCarthy, Martijn L. T. M. Müller, Philip Murphy, Diane Stephenson
Publikováno v:
Clinical and Translational Science, Vol 16, Iss 3, Pp 383-397 (2023)
Abstract The US Food and Drug Administration (FDA) has publicly recognized the importance of improving drug development efficiency, deeming translational biomarkers a top priority. The use of imaging biomarkers has been associated with increased rate
Externí odkaz:
https://doaj.org/article/280ee2cdd5ac4a9d8191db1ba81f6e17
Autor:
Haotian Zou, Varun Aggarwal, Glenn T. Stebbins, Martijn L. T. M. Müller, Jesse M. Cedarbaum, Anne Pedata, Diane Stephenson, Tanya Simuni, Sheng Luo
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 11, Iss 10, Pp 1382-1392 (2022)
Abstract The Movement Disorder Society revised version of the Unified Parkinson’s Disease Rating Scale (MDS‐UPDRS) parts 2 and 3 reflect patient‐reported functional impact and clinician‐reported severity of motor signs of Parkinson’s diseas
Externí odkaz:
https://doaj.org/article/ee3e3e53b9774dd6a46eb395e7981514
Autor:
George Roussos, Teresa Ruiz Herrero, Derek L. Hill, Ariel V. Dowling, Martijn L. T. M. Müller, Luc J. W. Evers, Jackson Burton, Adrian Derungs, Katherine Fisher, Krishna Praneeth Kilambi, Nitin Mehrotra, Roopal Bhatnagar, Sakshi Sardar, Diane Stephenson, Jamie L. Adams, E. Ray Dorsey, Josh Cosman
Publikováno v:
npj Digital Medicine, Vol 5, Iss 1, Pp 1-10 (2022)
Abstract Smartphones and wearables are widely recognised as the foundation for novel Digital Health Technologies (DHTs) for the clinical assessment of Parkinson’s disease. Yet, only limited progress has been made towards their regulatory acceptabil
Externí odkaz:
https://doaj.org/article/db03089d79b34210b7b6df5f8e088dd6
Autor:
Sygrid van der Zee, Prabesh Kanel, Martijn L. T. M. Müller, Teus van Laar, Nicolaas I. Bohnen
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
BackgroundDegeneration of the cholinergic system plays an important role in cognitive impairment in Parkinson’s disease (PD). Positron emission tomography (PET) imaging using the presynaptic vesicular acetylcholine transporter (VAChT) tracer [18F]F
Externí odkaz:
https://doaj.org/article/378222834d5f47fbaefb1bbe55b4a03e
Publikováno v:
BMC Geriatrics, Vol 20, Iss 1, Pp 1-8 (2020)
Abstract Background Physical inactivity is prevalent in older adults with type 2 diabetes mellitus (T2DM) and may exacerbate their clinical symptoms. The aim of this study was to examine the feasibility of 4-h regular versus more dynamic standing ses
Externí odkaz:
https://doaj.org/article/c5bc6e74b0ac4a7cb7ef3ea103547dcb
Autor:
Derek L. Hill, Diane Stephenson, Jordan Brayanov, Kasper Claes, Reham Badawy, Sakshi Sardar, Katherine Fisher, Susan J. Lee, Anthony Bannon, George Roussos, Tairmae Kangarloo, Viktorija Terebaite, Martijn L. T. M. Müller, Roopal Bhatnagar, Jamie L. Adams, E. Ray Dorsey, Josh Cosman
Publikováno v:
Sensors, Vol 22, Iss 6, p 2136 (2022)
Sensor data from digital health technologies (DHTs) used in clinical trials provides a valuable source of information, because of the possibility to combine datasets from different studies, to combine it with other data types, and to reuse it multipl
Externí odkaz:
https://doaj.org/article/ac5573163f6e4dee8e9be0e3c5b270ec
Autor:
Chao Gao, Hanbo Sun, Tuo Wang, Ming Tang, Nicolaas I. Bohnen, Martijn L. T. M. Müller, Talia Herman, Nir Giladi, Alexandr Kalinin, Cathie Spino, William Dauer, Jeffrey M. Hausdorff, Ivo D. Dinov
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-21 (2018)
Abstract In this study, we apply a multidisciplinary approach to investigate falls in PD patients using clinical, demographic and neuroimaging data from two independent initiatives (University of Michigan and Tel Aviv Sourasky Medical Center). Using
Externí odkaz:
https://doaj.org/article/f3f7a8e86fd34267bf9c85a913def857
Autor:
Nicolaas I. Bohnen, Prabesh Kanel, Stiven Roytman, Peter J. H. Scott, Robert A. Koeppe, Roger L. Albin, Kevin A. Kerber, Martijn L. T. M. Müller
Publikováno v:
Journal of Neural Transmission. 129:1001-1009
To examine regional cerebral vesicular acetylcholine transporter (VAChT) ligand [
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1070bb9120be371ecab3b5fe2285cc47
https://doi.org/10.1007/s00702-022-02523-3
https://doi.org/10.1007/s00702-022-02523-3