Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Martijn J. Wilmer"'
Autor:
Marit Keuper-Navis, Markus Walles, Birk Poller, Adam Myszczyszyn, Thomas K. van der Made, Joanne Donkers, Hossein Eslami Amirabadi, Martijn J. Wilmer, Saskia Aan, Bart Spee, Rosalinde Masereeuw, Evita van de Steeg
Publikováno v:
Pharmacological Research, Vol 195, Iss , Pp 106853- (2023)
Organ-on-chip (OoC) technology has led to in vitro models with many new possibilities compared to conventional in vitro and in vivo models. In this review, the potential of OoC models to improve the prediction of human oral bioavailability and intrin
Externí odkaz:
https://doaj.org/article/06d95e9d904945618f9e6018cbd79e94
Autor:
Manoe J. Janssen, Tom T.G. Nieskens, Tessa A.M. Steevels, Pedro Caetano-Pinto, Dirk den Braanker, Melissa Mulder, Yolanda Ponstein, Shaun Jones, Rosalinde Masereeuw, Cathaline den Besten, Martijn J. Wilmer
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 18, Iss , Pp 298-307 (2019)
Antisense oligonucleotide therapy has been reported to be associated with renal injury. Here, the mechanism of reversible proteinuria was investigated by combining clinical, pre-clinical, and in vitro data. Urine samples were obtained from Duchenne m
Externí odkaz:
https://doaj.org/article/b87e4abe3c8947bda573024c4f50791f
Autor:
Milos Mihajlovic, Lambertus P. van den Heuvel, Joost G. Hoenderop, Jitske Jansen, Martijn J. Wilmer, Annemarie J. F. Westheim, Wil A. Allebes, Dimitrios Stamatialis, Luuk B. Hilbrands, Rosalinde Masereeuw
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Abstract Novel renal replacement therapies, such as a bioartificial kidney (BAK), are needed to improve current hemodialysis treatment of end-stage renal disease (ESRD) patients. As BAK applications may reveal safety concerns, we assessed the alloimm
Externí odkaz:
https://doaj.org/article/108b767fdee94ce88e5583af35dafa74
Autor:
Joost P. Schoeber, Elena Levtchenko, Lambertus P. van den Heuvel, Dorien Reijnders, Martijn J. Wilmer, Karen Peeters, Rosalinde Masereeuw
Publikováno v:
Pharmaceutics, Vol 3, Iss 4, Pp 782-792 (2011)
P-glycoprotein (P-gp) is an ATP-dependent transporter localized at the apical membrane of the kidney proximal tubules, which plays a role in the efflux of cationic and amphipathic endogenous waste products and xenobiotics, such as drugs, into urine.
Externí odkaz:
https://doaj.org/article/88f1588550094a7782e6279e180e8963
Autor:
Martijn J. Wilmer, Ernst Ahlberg, Mikael Persson, Simone H. Stahl, Anna-Karin Sjögren, Malin Forsgard, Jorrit J. Hornberg, Lucas Milton, Katarina Breitholtz
Publikováno v:
Archives of Toxicology, 92, 3175-3190
Archives of Toxicology, 92, 10, pp. 3175-3190
Archives of Toxicology, 92, 10, pp. 3175-3190
Contains fulltext : 196765.pdf (Publisher’s version ) (Closed access) Drug-induced nephrotoxicity is a major concern in the clinic and hampers the use of available treatments as well as the development of innovative medicines. It is typically disco
Autor:
Frans G. M. Russel, Martijn J. Wilmer
Publikováno v:
Handbook of Biomarkers and Precision Medicine ISBN: 9780429202872
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d9a66c8a6f1470a4615f338b49f2e44a
https://doi.org/10.1201/9780429202872-10
https://doi.org/10.1201/9780429202872-10
Autor:
Henriëtte L. Lanz, Paul Vulto, Martijn J. Wilmer, Chee Ping Ng, Rosalinde Masereeuw, Laura Suter-Dick
Publikováno v:
Trends in Biotechnology, 34, 156-70
Trends in Biotechnology, 34, 2, pp. 156-70
Trends in Biotechnology, 34, 2, pp. 156-70
Contains fulltext : 170854.pdf (Publisher’s version ) (Closed access) Improved model systems to predict drug efficacy, interactions, and drug-induced kidney injury (DIKI) are crucially needed in drug development. Organ-on-a-chip technology is a sui
Autor:
Frans G. M. Russel, Alexander H. van Asbeck, Janny G. P. Peters, Neslihan N. Tavraz, Rosalinde Masereeuw, Thomas Friedrich, Tom T. G. Nieskens, Martijn J. Wilmer, Daphne Korte, Katja Jansen, Dina Dabaghie
Publikováno v:
Drug Metabolism and Disposition, 46, 592-599
Drug Metabolism and Disposition, 46, 5, pp. 592-599
Drug Metabolism and Disposition, 46, 5, pp. 592-599
Contains fulltext : 193213.pdf (Publisher’s version ) (Open Access) Cisplatin is a cytostatic drug used for treatment of solid organ tumors. The main adverse effect is organic cation transporter 2 (OCT2)-mediated nephrotoxicity, observed in 30% of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::095afbd7d7437c076bc1c5acad7a4e00
http://hdl.handle.net/2066/193213
http://hdl.handle.net/2066/193213
Autor:
Rosalinde Masereeuw, Stefania Geraci, Albert Bilos, Martijn J. Wilmer, Peter Pickkers, B Kraenzlin, Norbert Gretz, Suzanne Heemskerk, Esther Peters
Publikováno v:
British Journal of Pharmacology. 172:4932-4945
BACKGROUND AND PURPOSE: Recently, two phase-II trials demonstrated improved renal function in critically ill patients with sepsis-associated acute kidney injury treated with the enzyme alkaline phosphatase. Here, we elucidated the dual active effect
Autor:
Michael Abecassis, Ahmed Abed, Massimo Abelli, Sarwat Ahmad, Mario Alessiani, Aynaa Alsharidi, Fiorella Altruda, Gabriella Amorese, Andrea Angeletti, Mario Angelico, Roberta Angelico, Maria L. Angelotti, Robert J. Applegate, Anthony Atala, Chiara Attanasio, David Axelrod, Yanik Bababekov, Joydeep Basu, Francesca Becherucci, P. Matthew Belford, Enrico Benedetti, Valentina Benedetti, Ariela Benigni, Timothy A. Bertram, Oriol Bestard, Joshua Blake, Ugo Boggi, Lauren Brasile, Jonathan S. Bromberg, Sophie Brouard, Matthew Brovold, George W. Burke, Mirela Busic, Zeeshan Butt, Silvia Caddeo, Stefano Calzone, Josep M. Campistol, Irene Carmagnola, Fiona Carty, Diego Castanares-Zapatero, Christos E. Chadjichristos, Brooke E. Chambers, Sindhu Chandran, Christos Chatziantoniou, Ashton Chen, Linda Chen, Xiwu Chen, Valeria Chiono, Manuel Chiusa, Gaetano Ciancio, Gianluca Ciardelli, Gino Coletti, Elisabeth Coll, Christine Collienne, Robert B. Colvin, Monica Cortinovis, A. Benedict Cosimi, Paolo Cravedi, Giuseppe D’Amico, Stefano Da Sacco, Richard Danger, Jacques Dantal, Alan J. Davidson, Letizia De Chiara, Johannes W. De Fijter, Gloria de la Rosa, Francis L. Delmonico, Junhong Deng, Corinne Deurdulian, Abritee Dhal, Paolo Dionigi, Beatriz Domínguez-Gil, Marek Drozdzik, Jean-Claude Dussaule, Lauren Edgar, Maria Francesca Egidi, Hany El Hennawy, Karen English, Matthew J. Everly, Sharmila Fagoonee, Elvira Smeralda Famulari, Alan C. Farney, Marina Figliuzzi, Marialuisa Framarino-dei-Malatesta, David E. Fumo, Elena Gagliardini, Lorenzo Gallon, Sanjay K. Gandhi, Michael D. Gautreaux, Anna Geraedts, Domenico Giannese, Pier C. Giulianotti, Michael S. Goligorsky, Adam Griesemar, Josep M. Grinyó, Angelika C. Gruessner, Rainer W.G. Gruessner, Bulang He, Eliot Heher, Bing Ho, Sarah A. Hosgood, Kiyohiko Hotta, Atul Humar, H. David Humes, Giuseppe Iaria, Barbara Imberti, Juan Carlos Izpisua Belmonte, Ina Jochmans, Ravi Katari, Panagiotis Kavvadas, Tatsuo Kawai, Carlos Kengla, Tristan Keys, Amritha Kidiyoor, Kengo Kidokoro, Deepali Kumar, Michael A. Kutcher, Quirino Lai, Pierre-François Laterre, Céleste Lebbé, Christophe Legendre, Rachel Lennon, Peng Li, Jen-Jar Lin, Melissa H. Little, Xiongbing Lu, John W. Ludlow, Beatriz Mahíllo, Rosalinde Masereeuw, Rafael Matesanz, Mirjana S. Matovinovic, Benedetta Mazzinghi, Serge Cedrick Mbiandjeu Toya, Scott McEwen, Fabio Melandro, Loredana Melchiorri, Madhav C. Menon, Majid Mirzazadeh, Samantha Montag, Robert A. Montgomery, Virginie Montiel, Nuria Montserrat, Marina Morigi, Christian C. Morrill, Michel Mourad, Sean V. Murphy, Patricia Murray, Tiziana Nardo, Paolo A. Netti, Mark Nguyen, Michael L. Nicholson, John M. O’Callaghan, Linda Ohler, Giuseppe Orlando, Kenji Osafune, Tetsu Oura, Anna Peired, Andrea Peloso, Zhenzhen Peng, Norberto Perico, Laura Perin, Vittorio Perrone, Paul Persad, János Peti-Peterdi, Astgik Petrosyan, Andrea Pietrabissa, Christopher J. Pino, Jacques Pirenne, Francesco Pisani, Rutger J. Ploeg, Esteban Porrini, Ambra Pozzi, Alberto Pugliese, Luigi Pugliese, Ton J. Rabelink, Teresa Rampino, Michael A. Rees, Marlies E.J. Reinders, Andrea Remuzzi, Giuseppe Remuzzi, Anne Riquier-Brison, Raquel G. Roca, Jeffrey Rogers, Paola Romagnani, Ivy A. Rosales, Norman D. Rosenblum, Cinzia Rota, Piero Ruggenenti, Francesca Ruini, Junichiro Sageshima, Fadi El Salem, Shaifali Sandal, Veronika Sander, Ilaria Santeramo, Renato M. Santos, Minnie Sarwal, Jigesh Shah, Aneesha A. Shetty, Lorenzo Silengo, Eric Siskind, Anton Skaro, Renaud Snanoudj, Shay Soker, Andrew M. South, Goce Spasovski, Robert J. Stratta, Charles Strom, Bart Stubenitsky, Riccardo Tamburrini, Qizhi Tang, Ekamol Tantissattamo, Masayuki Tasaki, Hisham Tchelepi, Elena Ticozzelli, Opas Traitanon, Matias Trillini, Ivo Tzvetanov, María O. Valentín, Flavio Vincenti, Fabio Vistoli, Jelle Vriend, Stephen J. Walker, Jason A. Wertheim, David F. Williams, Bettina Wilm, Martijn J. Wilmer, Rebecca A. Wingert, Xavier Wittebole, Yun Xia, Christodoulos Xinaris, Kazuhiko Yamada, Takashi Yokoo, Shinya Yokote, Maarten L. Zandvliet, Roy Zent, Yuanyuan Zhang, David X. Zhao, Lihui Zhao, Susan Y. Zhao
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9ebe7748e893178188911ac178706eee
https://doi.org/10.1016/b978-0-12-801734-0.00094-1
https://doi.org/10.1016/b978-0-12-801734-0.00094-1