Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Martijn J. Schuijs"'
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Eosinophils are typically a minority population of circulating granulocytes being released from the bone-marrow as terminally differentiated cells. Besides their function in the defense against parasites and in promoting allergic airway inflammation,
Externí odkaz:
https://doaj.org/article/483cb85f53464d408b3e9cbd89adb5a6
Publikováno v:
ALLERGOLOGIE
The prevalence of allergic disease has increased significantly over the past decades. Although allergies are inherently multifactorial and heterogenous; environmental, maternal, and early-life microbial exposures could strongly modify disease risk. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c74278d14d3d0cff0d8a19c8e30c9922
https://doi.org/10.5414/alx02327e
https://doi.org/10.5414/alx02327e
Autor:
Charlotte J. Imianowski, Sarah K. Whiteside, Teresa Lozano, Alexander C. Evans, Jayme D. Benson, Christina J.F. Courreges, Firas Sadiyah, Colleen M. Lau, Nordin D. Zandhuis, Francis M. Grant, Martijn J. Schuijs, Panagiota Vardaka, Paula Kuo, Elizabeth J. Soilleux, Jie Yang, Joseph C. Sun, Tomohiro Kurosaki, Klaus Okkenhaug, Timotheus Y.F. Halim, Rahul Roychoudhuri
Publikováno v:
Journal of Experimental Medicine. 219
Natural killer (NK) cells are critical to immune surveillance against infections and cancer. Their role in immune surveillance requires that NK cells are present within tissues in a quiescent state. Mechanisms by which NK cells remain quiescent in ti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fecacc7251e7923f5e10f96d7c256dc8
https://doi.org/10.1084/jem.20211476
https://doi.org/10.1084/jem.20211476
Autor:
Jonathan Maelfait, Kenny Roose, Lars Vereecke, Conor Mc Guire, Mozes Sze, Martijn J Schuijs, Monique Willart, Lorena Itati Ibañez, Hamida Hammad, Bart N Lambrecht, Rudi Beyaert, Xavier Saelens, Geert van Loo
Publikováno v:
PLoS Pathogens, Vol 12, Iss 1, p e1005410 (2016)
A20 negatively regulates multiple inflammatory signalling pathways. We here addressed the role of A20 in club cells (also known as Clara cells) of the bronchial epithelium in their response to influenza A virus infection. Club cells provide a niche f
Externí odkaz:
https://doaj.org/article/b353388aaad34cc2808b975704730a7d
Autor:
Martijn J Schuijs, Susanne Hartmann, Murray E Selkirk, Luke B Roberts, Peter J M Openshaw, Corinna Schnoeller
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0161885 (2016)
Respiratory Syncytial Virus (RSV) is a major pathogen causing low respiratory tract disease (bronchiolitis), primarily in infants. Helminthic infections may alter host immune responses to both helminths and to unrelated immune triggers. For example,
Externí odkaz:
https://doaj.org/article/fe53840812094a7d825ad2a1eba1e2b2
Autor:
Timotheus Y.F. Halim, Shwethaa Raghunathan, Tobias Janowitz, Erwin F. Wagner, Martijn J. Schuijs, Duncan I. Jodrell, Michele Petruzzelli, Michele Vacca, Christian Frezza, Zoe Hall, David Perera, Edoardo Gaude, Miriam Ferrer, Ashok R. Venkitaraman, Michael J. Lukey
An elevated neutrophil-to-lymphocyte ratio negatively predicts the outcome of patients with cancer and is associated with cachexia, the terminal wasting syndrome. Here, we show using murine model systems of colorectal and pancreatic cancer that neutr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d6d1675fc35cbbd4f83849c18c3ee51c
https://doi.org/10.1101/2021.08.11.455851
https://doi.org/10.1101/2021.08.11.455851
Publikováno v:
TRENDS IN IMMUNOLOGY
Trends Immunol
Trends in Immunology, 40(1), 22-34. Elsevier Ltd.
Trends in Immunology
Trends Immunol
Trends in Immunology, 40(1), 22-34. Elsevier Ltd.
Trends in Immunology
Dendritic cells (DCs) are critical for the activation of naive CD4(+) T cells and are considered professional antigen-presenting cells (APCs), as are macrophages and B cells. Recently, several innate type 2 immune cells, such as basophils, mast cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab94f36c5a1c9561edd8f69d23e1bbab
https://doi.org/10.1016/j.it.2018.11.001
https://doi.org/10.1016/j.it.2018.11.001
Autor:
Ulf Gehrmann, Karl J. Staples, Bart N. Lambrecht, Ramachandramouli Budida, Danen Cunoosamy, Tina Baker, Bastian R. Angermann, Martijn J. Schuijs, Kristofer Thörn, Faye Melville, Johan Mattsson, Gabriel Skogberg, Elisabeth Israelsson, Thomas Naessens, Yannick Morias, Eva Hamrud
Publikováno v:
American Journal of Respiratory and Critical Care Medicine
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
American Journal of Respiratory and Critical Care Medicine, 202(4), 535-548. American Thoracic Society
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
American Journal of Respiratory and Critical Care Medicine, 202(4), 535-548. American Thoracic Society
Rationale: Emerging evidence supports a crucial role for tertiary lymphoid organs (TLOs) in chronic obstructive pulmonary disease (COPD) progression. However, mechanisms of immune cell activation leading to TLOs in COPD remain to be defined. Objectiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36e113264a6c0931456131608a5a6786
https://eprints.soton.ac.uk/439225/
https://eprints.soton.ac.uk/439225/
Publikováno v:
Annals of the New York Academy of Sciences. 1417:87-103
Group 2 innate lymphoid cells (ILC2) are innate immune cells that respond rapidly to their environment through soluble inflammatory mediators and cell-to-cell interactions. As tissue-resident sentinels, ILC2 help orchestrate localized type 2 immune r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c2860804d7d345f2ca6ddfa8f1ccad8
https://doi.org/10.1111/nyas.13604
https://doi.org/10.1111/nyas.13604
Autor:
Erik Melén, Rudolph Valenta, Fanny Rancière, C. Tischer, I. Skrindo, Hamida Hammad, V. Anastasova, Leda Chatzi, C. Hohman, Magnus Wickman, M P Fantini, M. Torrent, Pascal Demoly, S. Palkonen, Esben Eller, Carsten Bindslev-Jensen, N. Anderson, A. Bedbrook, Torsten Zuberbier, Rachel Nadif, Francesco Forastiere, K. Wenger, Sybille Koletzko, I. Annesi-Maesano, Jonathan M. Coquet, Yvan Saeys, Joachim Heinrich, Steffen Lau, Marit Westman, Bénédicte Jacquemin, L. von Hertzen, M. Standl, Marta Benet, Martijn J. Schuijs, Mirela Curin, Dirkje S. Postma, Valérie Siroux, Bart N. Lambrecht, E. Minina, Christian Lupinek, Vegard Hovland, Irina Lehmann, Jordi Sunyer, Dieter Maier, Stephane Ballereau, Anna Asarnoj, Jean Bousquet, Isabelle Momas, A. Rial-Sebbag, Gerard H. Koppelman, Cezmi A. Akdis, Isabelle Pin, A. von Berg, Henriette A. Smit, Manolis Kogevinas, Beatrix Gerhard, Claus Bachert, Emilie Burte, S. Guerra, Sandra Wieser, Bert Brunekreef, Johann Pellet, Ulrike Gehring, Renata Kiss, Petter Mowinckel, Cheng-Jian Xu, Anne Cambon-Thomsen, Jordi Mestres, Theresa Keller, Martijn C. Nawijn, Ferran Ballester, N. Ballardini, Tari Haahtela, Mariona Pinart, Charles Auffray, J. Garcia-Aymerich, J. Just, R. Albang, Marek L. Kowalski, Marjan Kerkhof, Inger Kull, Mika J. Mäkelä, G. De Carlo, J. De Vocht, Kai-Håkon Carlsen, Sam Oddie, A. Arno, Rosemary R. C. McEachan, X. Basagana, Thomas Keil, Daniela Porta, M. Akdis, Anna Bergström, Nathanaël Lemonnier, Raphaëlle Varraso, John Wright, Josep M. Antó, K. C. Lødrup Carlsen, D. Smagghe
Publikováno v:
Allergy. 71:1513-1525
MeDALL (Mechanisms of the Development of ALLergy; EU FP7-CP-IP; Project No: 261357; 2010-2015) has proposed an innovative approach to develop early indicators for the prediction, diagnosis, prevention and targets for therapy. MeDALL has linked epidem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e0dd042b409cd7901a33dbbd20c82865
https://doi.org/10.1111/all.12880
https://doi.org/10.1111/all.12880