Heritability of Urinary Amines, Organic Acids, and Steroid Hormones in Children

Autor: Fiona A. Hagenbeek, Jenny van Dongen, René Pool, Amy C. Harms, Peter J. Roetman, Vassilios Fanos, Britt J. van Keulen, Brian R. Walker, Naama Karu, Hilleke E. Hulshoff Pol, Joost Rotteveel, Martijn J. J. Finken, Robert R. J. M. Vermeiren, Cornelis Kluft, Meike Bartels, Thomas Hankemeier, Dorret I. Boomsma

Publikováno v: Metabolites, Vol 12, Iss 6, p 474 (2022)

Variation in metabolite levels reflects individual differences in genetic and environmental factors. Here, we investigated the role of these factors in urinary metabolomics data in children. We examined the effects of sex and age on 86 metabolites, a

Externí odkaz: https://doaj.org/article/688ad8fdf81a452d979a3e4613da6de5

Methods to Assess Fat Mass in Infants and Young Children: A Comparative Study Using Skinfold Thickness and Air-Displacement Plethysmography

Autor: Stefanie M. P. Kouwenhoven, Nadja Antl, Jos W. R. Twisk, Berthold V. Koletzko, Martijn J. J. Finken, Johannes B. van Goudoever

Publikováno v: Life, Vol 11, Iss 2, p 75 (2021)

Background: Traditionally, fat mass is estimated using anthropometric models. Air-displacement plethysmography (ADP) is a relatively new technique for determining fat mass. There is limited information on the agreement between these methods in infant

Externí odkaz: https://doaj.org/article/835af0b8ce7b406bbc7e5d50745a444d

Biallelic variants in the SLC13A1 sulfate transporter gene cause hyposulfatemia with a mild spondylo-epi-metaphyseal dysplasia

Autor: Jiddeke M. van de Kamp, Arend Bökenkamp, Desiree E. C. Smith, Mirjam M. C. Wamelink, Erwin E. W. Jansen, Eduard A. Struys, Quinten Waisfisz, Marieke Verkleij, Michaela F. Hartmann, Rong Wang, Stefan A. Wudy, Chiara Paganini, Antonio Rossi, Martijn J. J. Finken

Publikováno v: van de Kamp, J M, Bökenkamp, A, Smith, D E C, Wamelink, M M C, Jansen, E E W, Struys, E A, Waisfisz, Q, Verkleij, M, Hartmann, M F, Wang, R, Wudy, S A, Paganini, C, Rossi, A & Finken, M J J 2023, ' Biallelic variants in the SLC13A1 sulfate transporter gene cause hyposulfatemia with a mild spondylo-epi-metaphyseal dysplasia ', Clinical Genetics, vol. 103, no. 1, pp. 45-52 . https://doi.org/10.1111/cge.14239
Clinical Genetics, 103(1), 45-52. Wiley-Blackwell

Sulfate is the fourth most abundant anion in human plasma but is not measured in clinical practice and little is known about the consequences of sulfate deficiency. Nevertheless, sulfation plays an essential role in the modulation of numerous compoun

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38f912b4df94fea3356cb682c253b22d
https://pubmed.ncbi.nlm.nih.gov/36175384

Long-term effects of a modified, low-protein infant formula on growth and body composition

Autor: Martijn J J Finken, Eline M. van der Beek, Stefanie M.P. Kouwenhoven, Bert J. M. van de Heijning, Berthold Koletzko, Jos W. R. Twisk, Marieke Abrahamse-Berkeveld, Nadja Antl, Johannes B. van Goudoever

Publikováno v: Clinical Nutrition, 40(6), 3914-3921. Churchill Livingstone
Kouwenhoven, S M P, Antl, N, Finken, M J J, Twisk, J W R, van der Beek, E M, Abrahamse-Berkeveld, M, van de Heijning, B J M, van Goudoever, J B & Koletzko, B V 2021, ' Long-term effects of a modified, low-protein infant formula on growth and body composition: Follow-up of a randomized, double-blind, equivalence trial ', Clinical Nutrition, vol. 40, no. 6, pp. 3914-3921 . https://doi.org/10.1016/j.clnu.2021.04.034

Background & aim: High protein intake in early life is associated with an increased risk of childhood obesity. Feeding a modified lower-protein (mLP) infant formula (1.7 g protein/100 kcal) until the age of 6 months is safe and supports adequate grow

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9a241b015f6fdab903afc61db4de41e
https://research.rug.nl/en/publications/d44f8757-9eb0-4e82-9e14-109bc7c4919a

Role of glucocorticoid metabolism in childhood obesity-associated hypertension

Autor: Martijn J J Finken, Aleid J G Wirix, Ines A von Rosenstiel-Jadoul, Bibian van der Voorn, Mai J M Chinapaw, Michaela F Hartmann, Joana E Kist-van Holthe, Stefan A Wudy, Joost Rotteveel

Publikováno v: Endocrine Connections, 11(7):e220130. Bioscientifica Ltd
Endocrine Connections, 11(7):e220130. BioScientifica Ltd.
Finken, M J J, Wirix, A J G, von Rosenstiel-Jadoul, I A, van der Voorn, B, Chinapaw, M J M, Hartmann, M F, Kist-van Holthe, J E, Wudy, S A & Rotteveel, J 2022, ' Role of glucocorticoid metabolism in childhood obesity-associated hypertension ', Endocrine Connections, vol. 11, no. 7, e220130 . https://doi.org/10.1530/EC-22-0130

Objective Childhood obesity is associated with alterations in hypothalamus–pituitary–adrenal axis activity. We tested the hypothesis that multiple alterations in the metabolism of glucocorticoids are required for the development of hypertension i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ad4ce86ec0d762b4d1844287d65331d
https://pure.eur.nl/en/publications/d1bfb5b1-c1bd-4eea-b8f0-bcb78420c935