Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Martijn H. A. van Attekum"'
Publikováno v:
Haematologica
The importance of the tumor microenvironment in chronic lymphocytic leukemia is widely accepted. Nevertheless, the understanding of the complex interplay between the various types of bystander cells and chronic lymphocytic leukemia cells is incomplet
Autor:
Jaco A. C. van Bruggen, Sabina Kersting, Martijn H. A. van Attekum, Arnon P. Kater, Erik Slinger, Emilie Reinen, Eric Eldering, M Cristina Lebre
Publikováno v:
Haematologica
Haematologica, 102(12), 2069-2076. Ferrata Storti Foundation
Haematologica, 102(12), 2069-2076. Ferrata Storti Foundation
Chronic lymphocytic leukemia (CLL) cells are provided with essential survival and proliferative signals in the lymph node microenvironment. Here, CLL cells engage in various interactions with bystander cells such as T cells and macrophages. Phenotypi
Publikováno v:
Cell Death Discovery, 2(1):16020. Nature Publishing Group
van Attekum, M, Terpstra, S, Reinen, E, Kater, A & Eldering, E 2016, ' Macrophage-mediated chronic lymphocytic leukemia cell survival is independent of APRIL signaling ', Cell Death Discovery, vol. 2, no. 1, 16020 . https://doi.org/10.1038/cddiscovery.2016.20
Cell death discovery, 2. Nature Publishing Group
Cell Death Discovery
van Attekum, M, Terpstra, S, Reinen, E, Kater, A & Eldering, E 2016, ' Macrophage-mediated chronic lymphocytic leukemia cell survival is independent of APRIL signaling ', Cell Death Discovery, vol. 2, no. 1, 16020 . https://doi.org/10.1038/cddiscovery.2016.20
Cell death discovery, 2. Nature Publishing Group
Cell Death Discovery
Survival of chronic lymphocytic leukemia (CLL) cells is mainly driven by interactions within the lymph node (LN) microenvironment with bystander cells such as T cells or cells from the monocytic lineage. Although the survival effect by T cells is lar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dc5f48cb7fd8316a56cac84fa22802b
https://research.vumc.nl/en/publications/f9c35c6f-ef62-4e32-a5e4-b6a1bc98237c
https://research.vumc.nl/en/publications/f9c35c6f-ef62-4e32-a5e4-b6a1bc98237c
Publikováno v:
Scientific reports, 6. Nature Publishing Group
Upon antigen encounter, the responsive B cell pool undergoes stringent selection which eliminates cells with low B cell receptor (BCR) affinity. Already before formation of the germinal center, activated B cells of low-affinity are negatively selecte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd000a41aaeee7343ea273275697d97f
https://pure.amc.nl/en/publications/antigenaffinity-controls-pregerminal-centser-b-cell-selection-by-promoting-mcl1-induction-through-baff-receptor-signaling(153b3079-50a0-4b87-8e56-9c6efa01e32f).html
https://pure.amc.nl/en/publications/antigenaffinity-controls-pregerminal-centser-b-cell-selection-by-promoting-mcl1-induction-through-baff-receptor-signaling(153b3079-50a0-4b87-8e56-9c6efa01e32f).html
Autor:
Rachel Thijssen, Jacqueline M. Tromp, Maria Fernanda Pascutti, René A. W. van Lier, Ester B. M. Remmerswaal, Marinus H. J. van Oers, Eric Eldering, Arnon P. Kater, Steven T. Pals, Margot Jak, Gregor G. W. van Bochove, Ingrid A. M. Derks, Martijn H. A. van Attekum, Dieuwertje M. Luijks
Publikováno v:
Blood, 122(17), 3010-3019. American Society of Hematology
Chronic lymphocytic leukemia (CLL) cells multiply in secondary lymphoid tissue, but the mechanisms leading to their proliferation are still uncertain. In addition to B-cell receptor (BCR)-triggered signals, other microenvironmental factors might well
Autor:
Sanne Terpstra, Arnon P. Kater, Erik Slinger, Eldering Eric, Martijn H. A. van Attekum, Emilie Reinen, Marieke von Lindern
Publikováno v:
Blood. 126:1715-1715
Survival of CLL cells critically depends on heterotypic communication with benign bystanders cells in micro-environmental niches such as lymph node (LN) tissue. Here, mesenchymal stromal cells and macrophages, in concert with CD40L expressing T cells