Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Martijn H J, van den Bosch"'
CD64 as novel molecular imaging marker for the characterization of synovitis in rheumatoid arthritis
Autor:
Wessel F. Theeuwes, Irene Di Ceglie, Daphne N. Dorst, Arjen B. Blom, Desiree L. Bos, Thomas Vogl, Sander W. Tas, Pilar Jimenez-Royo, Mats Bergstrom, Matthew Cleveland, Peter M. van der Kraan, Peter Laverman, Marije I. Koenders, Peter L. van Lent, Martijn H. J. van den Bosch
Publikováno v:
Arthritis Research & Therapy, Vol 25, Iss 1, Pp 1-15 (2023)
Abstract Background Rheumatoid arthritis (RA) is one of the most prevalent and debilitating joint diseases worldwide. RA is characterized by synovial inflammation (synovitis), which is linked to the development of joint destruction. Magnetic resonanc
Externí odkaz:
https://doaj.org/article/2aad6123f8ac4ee5adcf05a7f4fb72f2
Autor:
Irene Di Ceglie, Peter L. E. M. van Lent, Edwin J. W. Geven, Marije I. Koenders, Arjen B. Blom, Thomas Vogl, Johannes Roth, Martijn H. J. van den Bosch
Publikováno v:
Arthritis Research & Therapy, Vol 23, Iss 1, Pp 1-12 (2021)
Abstract Background Excessive osteoclast activity, which is strongly stimulated by pro-inflammatory mediators, results in bone and cartilage degeneration as central features of many arthritides. Levels of the alarmin S100A8/A9 and interleukin (IL)-1
Externí odkaz:
https://doaj.org/article/007fde91b5b342df9e647aa4c1e5e630
Post-traumatic knee osteoarthritis; the role of inflammation and hemarthrosis on disease progression
Autor:
Bob J. Evers, Martijn H. J. Van Den Bosch, Arjen B. Blom, Peter M. van der Kraan, Sander Koëter, Rogier M. Thurlings
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
Knee injuries such as anterior cruciate ligament ruptures and meniscal injury are common and are most frequently sustained by young and active individuals. Knee injuries will lead to post-traumatic osteoarthritis (PTOA) in 25–50% of patients. Mecha
Externí odkaz:
https://doaj.org/article/8a6c2c2070974a60a2f9f826d5a3ac3d
Autor:
Juliana P. Vago, Natália Valdrighi, Esmeralda N. Blaney-Davidson, Daniel L. A. H. Hornikx, Margot Neefjes, María E. Barba-Sarasua, Nathalie G. M. Thielen, Martijn H. J. van den Bosch, Peter M. van der Kraan, Marije I. Koenders, Flávio A. Amaral, Fons A. J. van de Loo
Publikováno v:
Pharmaceuticals, Vol 16, Iss 5, p 703 (2023)
Osteoarthritis (OA) is the most prevalent joint disease, and it is characterized by cartilage degeneration, synovitis, and bone sclerosis, resulting in swelling, stiffness, and joint pain. TAM receptors (Tyro3, Axl, and Mer) play an important role in
Externí odkaz:
https://doaj.org/article/047bc96dcbe34cb9b01ef0b135fe48be
Autor:
Irene Di Ceglie, Giuliana Ascone, Niels A. J. Cremers, Annet W. Sloetjes, Birgitte Walgreen, Thomas Vogl, Johannes Roth, J. Sjef Verbeek, Fons A. J. van de Loo, Marije I. Koenders, Peter M. van der Kraan, Arjen B. Blom, Martijn H. J. van den Bosch, Peter L. E. M. van Lent
Publikováno v:
Arthritis Research & Therapy, Vol 20, Iss 1, Pp 1-15 (2018)
Abstract Background Osteoclast-mediated bone erosion is a central feature of rheumatoid arthritis (RA). Immune complexes, present in a large percentage of patients, bind to Fcγ receptors (FcγRs), thereby modulating the activity of immune cells. In
Externí odkaz:
https://doaj.org/article/9d7253effde542e1a9c44878e23e232e
Autor:
Nik N. L. Kruisbergen, Irene Di Ceglie, Yvonne van Gemert, Birgitte Walgreen, Monique M. A. Helsen, Annet W. Slöetjes, Marije I. Koenders, Fons A. J. van de Loo, Johannes Roth, Thomas Vogl, Peter M. van der Kraan, Arjen B. Blom, Peter L. E. M. van Lent, Martijn H. J. van den Bosch
Publikováno v:
Antioxidants, Vol 10, Iss 11, p 1660 (2021)
Osteoarthritis (OA) is a destructive disease of the joint with age and obesity being its most important risk factors. Around 50% of OA patients suffer from inflammation of the synovial joint capsule, which is characterized by increased abundance and
Externí odkaz:
https://doaj.org/article/78cf3de17a744173a88dbeea58163c1d
Autor:
Niels A. J. Cremers, Martijn H. J. van den Bosch, Stephanie van Dalen, Irene Di Ceglie, Giuliana Ascone, Fons van de Loo, Marije Koenders, Peter van der Kraan, Annet Sloetjes, Thomas Vogl, Johannes Roth, Edwin J. W. Geven, Arjen B. Blom, Peter L. E. M. van Lent
Publikováno v:
Arthritis Research & Therapy, Vol 19, Iss 1, Pp 1-15 (2017)
Abstract Background Monocytes are dominant cells present within the inflamed synovium during osteoarthritis (OA). In mice, two functionally distinct monocyte subsets are described: pro-inflammatory Ly6Chigh and patrolling Ly6Clow monocytes. Alarmins
Externí odkaz:
https://doaj.org/article/000ad2f4ec3f47dc9d28f7482a1ea756
Autor:
Bartijn C. H. Pieters, Alfredo Cappariello, Martijn H. J. van den Bosch, Peter L. E. M. van Lent, Anna Teti, Fons A. J. van de Loo
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Extracellular vesicles are a heterogeneous group of cell-derived membranous structures, which facilitate intercellular communication. Recent studies have highlighted the importance of extracellular vesicles in bone homeostasis, as mediators of crosst
Externí odkaz:
https://doaj.org/article/605f9676c5824d79a8960daa56856dc9
Autor:
Stephanie C. M. van Dalen, Arjen B. Blom, Birgitte Walgreen, Annet W. Slöetjes, Monique M. A. Helsen, Edwin J. W. Geven, Menno ter Huurne, Thomas Vogl, Johannes Roth, Fons A. J. van de Loo, Marije I. Koenders, Louis Casteilla, Peter M. van der Kraan, Martijn H. J. van den Bosch, Peter L. E. M. van Lent
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Background: Injection of adipose-derived mesenchymal stromal cells (ASCs) into murine knee joints after induction of inflammatory collagenase-induced osteoarthritis (CiOA) reduces development of joint pathology. This protection is only achieved when
Externí odkaz:
https://doaj.org/article/6ad2b9a22dd747d49bfb41f920fc06d9
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2582
The matricellular protein Wnt-induced secreted protein 1 (WISP1) is the fourth member of the CCN family of proteins, which has been shown to affect tissues of the musculoskeletal system. In the context of the musculoskeletal disorder osteoarthritis,