Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Martijn Gloerich"'
Autor:
Antoine A. Khalil, Daan Smits, Peter D. Haughton, Thijs Koorman, Karin A. Jansen, Mathijs P. Verhagen, Mirjam van der Net, Kitty van Zwieten, Lotte Enserink, Lisa Jansen, Abdelrahman G. El-Gammal, Daan Visser, Milena Pasolli, Max Tak, Denise Westland, Paul J. van Diest, Cathy B. Moelans, M. Guy Roukens, Sandra Tavares, Anne-Marie Fortier, Morag Park, Riccardo Fodde, Martijn Gloerich, Fried. J. T. Zwartkruis, Patrick WB. Derksen, Johan de Rooij
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Dense and aligned Collagen I fibers are associated with collective cancer invasion led by protrusive tumor cells, leader cells. In some breast tumors, a population of cancer cells (basal-like cells) maintain several epithelial characteristic
Externí odkaz:
https://doaj.org/article/50e49d8f27e74b6aa43d0874b11c6389
Autor:
Esther Strating, Mathijs P. Verhagen, Emerens Wensink, Ester Dünnebach, Liza Wijler, Itziar Aranguren, Alberto Sanchez De la Cruz, Niek A. Peters, Joris H. Hageman, Mirjam M. C. van der Net, Susanne van Schelven, Jamila Laoukili, Riccardo Fodde, Jeanine Roodhart, Stefan Nierkens, Hugo Snippert, Martijn Gloerich, Inne Borel Rinkes, Sjoerd G. Elias, Onno Kranenburg
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundPoor prognosis in colon cancer is associated with a high content of cancer-associated fibroblasts (CAFs) and an immunosuppressive tumor microenvironment. The relationship between these two features is incompletely understood. Here, we aimed
Externí odkaz:
https://doaj.org/article/90ab2b9cb2c4478f87f361dda37eab04
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
Cell–cell adhesion and oriented cell division play key roles in tissue architecture, but how they are coordinated is not known. Here, the authors show that E-cadherin interacts with LGN, and thereby provides a cortical cue that serves to stabilize
Externí odkaz:
https://doaj.org/article/55dcdce0fb18402db21b35a74521e6d5
Publikováno v:
F1000Research, Vol 8 (2019)
Mechanical forces drive the remodeling of tissues during morphogenesis. This relies on the transmission of forces between cells by cadherin-based adherens junctions, which couple the force-generating actomyosin cytoskeletons of neighboring cells. Mor
Externí odkaz:
https://doaj.org/article/d73abc2064584a36b5ade948bc890b63
Autor:
Hugo J.G. Snippert, Onno Kranenburg, Michiel Vermeulen, Jacco van Rheenen, Martijn Gloerich, Prisca Liberali, Inne H.M. Borel Rinkes, Ingrid Verlaan-Klink, Joris H. Hageman, Gustavo de Medeiros, Mirjam C. van der Net, Arianna Fumagalli, Lisa van Voorthuijsen, Rik G.H. Lindeboom, Koen C. Oost, Niek A. Peters, Maria C. Heinz
Supplementary Data from Liver Colonization by Colorectal Cancer Metastases Requires YAP-Controlled Plasticity at the Micrometastatic Stage
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03c4c4232fb540192e9921ef70f78607
https://doi.org/10.1158/0008-5472.22431123
https://doi.org/10.1158/0008-5472.22431123
Autor:
Hugo J.G. Snippert, Onno Kranenburg, Michiel Vermeulen, Jacco van Rheenen, Martijn Gloerich, Prisca Liberali, Inne H.M. Borel Rinkes, Ingrid Verlaan-Klink, Joris H. Hageman, Gustavo de Medeiros, Mirjam C. van der Net, Arianna Fumagalli, Lisa van Voorthuijsen, Rik G.H. Lindeboom, Koen C. Oost, Niek A. Peters, Maria C. Heinz
Micrometastases of colorectal cancer can remain dormant for years prior to the formation of actively growing, clinically detectable lesions (i.e., colonization). A better understanding of this step in the metastatic cascade could help improve metasta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49935a71331f7c12f1dfc920e1314641
https://doi.org/10.1158/0008-5472.c.6513804
https://doi.org/10.1158/0008-5472.c.6513804
Publikováno v:
Current biology : CB. 32(14)
The vertebrate intestine experiences a range of intrinsically generated and external forces during both development and adult homeostasis. It is increasingly understood how the coordination of these forces shapes the intestine through organ-scale fol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81342d13a001a1fbcf47a4bd72c5a051
https://pubmed.ncbi.nlm.nih.gov/35882203
https://pubmed.ncbi.nlm.nih.gov/35882203
Autor:
Maria C. Heinz, Niek A. Peters, Koen C. Oost, Rik G.H. Lindeboom, Lisa van Voorthuijsen, Arianna Fumagalli, Mirjam C. van der Net, Gustavo de Medeiros, Joris H. Hageman, Ingrid Verlaan-Klink, Inne H.M. Borel Rinkes, Prisca Liberali, Martijn Gloerich, Jacco van Rheenen, Michiel Vermeulen, Onno Kranenburg, Hugo J.G. Snippert
Publikováno v:
Cancer Research, 82, 1953-1968
Cancer Research, 82, 10, pp. 1953-1968
Cancer Research, 82, 10, pp. 1953-1968
Micrometastases of colorectal cancer can remain dormant for years prior to the formation of actively growing, clinically detectable lesions (i.e., colonization). A better understanding of this step in the metastatic cascade could help improve metasta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56ee094c01da174dcd6d0aa74af53634
http://hdl.handle.net/2066/250973
http://hdl.handle.net/2066/250973
Autor:
M. J. Vliem, M. Bosch-Padros, Xavier Trepat, Nicolas Borghi, H. Canever, Martijn Gloerich, Lisa Donker, Willem-Jan Pannekoek, M. Gomez-Gonzalez
Epithelial cell divisions must be tightly coordinated with cell loss to preserve epithelial integrity. However, it is not well understood how the rate of epithelial cell division adapts to changes in cell number, for instance during homeostatic turno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cc99796aa2fcf6d3b86c11d52db1c553
https://doi.org/10.1101/2021.11.29.470352
https://doi.org/10.1101/2021.11.29.470352
Autor:
Joleen S. Cheah, Chi-Fu Yen, Willem-Jan Pannekoek, Martijn Gloerich, Andrew Vae Priest, Ramesh Koirala, Sanjeevi Sivasankar, Soichiro Yamada
Publikováno v:
Proc Natl Acad Sci U S A
Cadherin cell-cell adhesion proteins play key roles in tissue morphogenesis and wound healing. Cadherin ectodomains bind in two conformations, X-dimers and strand-swap dimers, with different adhesive properties. However, the mechanisms by which cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::052df82372d8123fc860dc403b6bc93c
https://pubmed.ncbi.nlm.nih.gov/34301871
https://pubmed.ncbi.nlm.nih.gov/34301871