Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Martijn Devrome"'
Publikováno v:
Frontiers in Neuroimaging, Vol 2 (2023)
With the increasing success of mapping brain networks and availability of multiple MR- and PET-based connectivity measures, the need for novel methodologies to unravel the structure and function of the brain at multiple spatial and temporal scales is
Externí odkaz:
https://doaj.org/article/64e55cd63ab44294bbad1556d791a227
Autor:
Joke De Vocht, Donatienne Van Weehaeghe, Fouke Ombelet, Pegah Masrori, Nikita Lamaire, Martijn Devrome, Hilde Van Esch, Mathieu Moisse, Michel Koole, Patrick Dupont, Koen Van Laere, Philip Van Damme
Publikováno v:
Cells, Vol 12, Iss 6, p 933 (2023)
Amyotrophic lateral sclerosis (ALS) is characterized by progressive loss of upper and lower motor neurons. In 10% of patients, the disorder runs in the family. Our aim was to study the impact of ALS-causing gene mutations on cerebral glucose metaboli
Externí odkaz:
https://doaj.org/article/6f55a6f86eb94abeb661be8a3a21aac4
Autor:
Martijn Devrome, Donatienne Van Weehaeghe, Joke De Vocht, Philip Van Damme, Koen Van Laere, Michel Koole
Publikováno v:
EJNMMI Research, Vol 8, Iss 1, Pp 1-10 (2018)
Abstract Background 18F-FDG brain PET measures metabolic changes in neurodegenerative disorders and may discriminate between different diseases even at an early stage. The objective of this study was to classify patients with amyotrophic lateral scle
Externí odkaz:
https://doaj.org/article/73c2dc513d3c4918b079de1c3f49f33d
With the increasing success of mapping brain networks and availability of multiple MR- and PET-based connectivity measures, the need for novel methodologies to unravel the structure and function of the brain at multiple spatial and temporal scales is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a68828ec5c6df87ff8db571832e05f40
https://doi.org/10.21203/rs.3.rs-1550618/v1
https://doi.org/10.21203/rs.3.rs-1550618/v1
Autor:
Michel Koole, Veerle Baekelandt, Anke Van der Perren, Cindy Casteels, Martijn Devrome, Koen Van Laere
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-8 (2019)
We investigated the glucose metabolism in an adeno-associated viral vector based alpha-synuclein rat model for Parkinson's disease (PD) using longitudinal 18F-FDG PET imaging, which resulted in an improved characterization of this animal model. We ge
Autor:
Martijn Devrome, June van Aalst, Michel Koole, Ahmadreza Rezaei, Koen Van Laere, Jenny Ceccarini, Donatienne Van Weehaeghe, Ahmed Radwan, Stefan Sunaert, Georg Schramm
Publikováno v:
European journal of nuclear medicine and molecular imagingReferences. 49(2)
Human ageing is associated with a regional reduction in cerebral neuronal activity as assessed by numerous studies on brain glucose metabolism and perfusion, grey matter (GM) density and white matter (WM) integrity. As glucose metabolism may impact e
Autor:
Michael A. van Es, Jeroen Blommaert, June van Aalst, Donatienne Van Weehaeghe, Daphne Stam, Koen Van Laere, Jenny Ceccarini, Martijn Devrome, Hilde Van Esch, Adriano Chiò, Joke De Vocht, Philip Van Damme, Marianne Verhaegen, Michel Koole, Nikita Lamaire, Patrick Dupont, Marco Pagani, Maxim De Schaepdryver, Rik Vandenberghe, Ahmed Radwan, Ahmadreza Rezaei, Jan Van den Stock, Georg Schramm, Koen Poesen, Mathieu Vandenbulcke, Leonard H. van den Berg, Nathalie Mertens
Importance During a time with the potential for novel treatment strategies, early detection of disease manifestations at an individual level in presymptomatic carriers of a hexanucleotide repeat expansion in the C9orf72 gene (preSxC9) is becoming inc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c23e0f5b0e45e5c9832c3d3d2241bc1
https://lirias.kuleuven.be/handle/123456789/661659
https://lirias.kuleuven.be/handle/123456789/661659
Autor:
Joël Mercier, Kim Serdons, Brigitte Lacroix, Paul Maguire, David Sciberras, Martijn Devrome, Koen Van Laere, Nathalie Mertens, June van Aalst, Michel Koole
PURPOSE: A [11C]UCB-J blocking study was performed in healthy volunteers to validate simplified, non-invasive measures for quantifying presynaptic SV2A expression using subcortical white matter as reference tissue. METHODS: Ninety minutes dynamic [11
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::612de3cfddfaf94021b3df8259a8fdc9
https://lirias.kuleuven.be/handle/123456789/628111
https://lirias.kuleuven.be/handle/123456789/628111
Autor:
Martijn, Devrome, Cindy, Casteels, Anke, Van der Perren, Koen, Van Laere, Veerle, Baekelandt, Michel, Koole
Publikováno v:
Scientific Reports
We investigated the glucose metabolism in an adeno-associated viral vector based alpha-synuclein rat model for Parkinson’s disease (PD) using longitudinal 18F-FDG PET imaging, which resulted in an improved characterization of this animal model. We
Autor:
Koen Van Laere, Philip Van Damme, Joke De Vocht, Donatienne Van Weehaeghe, Michel Koole, Martijn Devrome
Publikováno v:
EJNMMI Research
EJNMMI Research, Vol 8, Iss 1, Pp 1-10 (2018)
EJNMMI Research, Vol 8, Iss 1, Pp 1-10 (2018)
BACKGROUND: 18F-FDG brain PET measures metabolic changes in neurodegenerative disorders and may discriminate between different diseases even at an early stage. The objective of this study was to classify patients with amyotrophic lateral sclerosis (A