Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Martijn Brugman"'
Autor:
Charlotte O’Brien Gore, Amy Billman, Suchete Hunjan, Jayne Colebrook, Desmond Choy, Wilson Li, Jack Haynes, Jennifer Wade, Emily Hobern, Louisa McDonald, Sophie Papa, Martijn Brugman, Shahram Kordasti, Claudia Montiel-Equihua
Publikováno v:
Molecular Therapy: Oncolytics, Vol 31, Iss , Pp 100749- (2023)
The antitumor activity of adoptive T cell therapies (ACT) is highly dependent on the expansion, persistence, and continued activity of adoptively transferred cells. Clinical studies using ACTs have revealed that products that possess and maintain les
Externí odkaz:
https://doaj.org/article/6d912f95605a4927b3659cf1aa41a91d
Autor:
Paulina Malach, Charlotte Kay, Chris Tinworth, Florence Patel, Bryan Joosse, Jennifer Wade, Marlene Rosa do Carmo, Brian Donovan, Martijn Brugman, Claudia Montiel-Equihua, Natalie Francis
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 31, Iss , Pp 101113- (2023)
Genetic modification of cells using viral vectors has shown huge therapeutic benefit in multiple diseases. However, inefficient transduction contributes to the high cost of these therapies. Several transduction-enhancing small molecules have previous
Externí odkaz:
https://doaj.org/article/e428393d42594d4b976d83894e5228ad
Autor:
Teng-Cheong, Ha, Maike, Stahlhut, Michael, Rothe, Gabi, Paul, Violetta, Dziadek, Michael, Morgan, Martijn, Brugman, Boris, Fehse, Olga, Kustikova, Axel, Schambach, Christopher, Baum
Publikováno v:
Human gene therapy. 32(9-10)
Retroviral insertional mutagenesis (RIM) is both a relevant risk in gene therapy and a powerful tool for identifying genes that enhance the competitiveness of repopulating hematopoietic stem and progenitor cells (HSPCs). However, focusing only on the
Autor:
Claudia Waskow, Tatyana Grinenko, Martijn Brugman, Boris Fehse, Ute Modlich, Connie Eaves, Adrian Schwarzer
Publikováno v:
Blood cells molecules and diseases, 50(4), 232-240
Here we report highlights of discussions and results presented at an International Workshop on Concepts and Models of Stem Cell Organization held on July 16th and 17th, 2012 in Dresden, Germany. The goal of the workshop was to undertake a systematic