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Akademický článek

Genesis and the Value-Institutional Evolution of Modernity

Autor: Victor S. Martianov

Publikováno v: Антиномии, Vol 22, Iss 3, Pp 42-71 (2022)

The article discusses key factors and directions of the value-institutional evolution of Modernity. It is argued that the progress of humankind towards global peace paradoxically turned into if not a denial, but a consistent radicalization of value-b

Externí odkaz: https://doaj.org/article/fe5d99e550394e629e1beb4d255fc310

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Akademický článek

Comprehensive evaluation of the test for 5′‐/3′‐end mRNA unbalanced expression as a screening tool for ALK and ROS1 fusions in lung cancer

Autor: Natalia V. Mitiushkina, Alexandr A. Romanko, Elena V. Preobrazhenskaya, Vladislav I. Tiurin, Tatiana I. Ermachenkova, Alexandr S. Martianov, Rimma S. Mulkidjan, Tatiana N. Sokolova, Maksim M. Kholmatov, Ilya V. Bizin, Alexandr O. Ivantsov, Olga S. Yatsuk, Olga A. Zaitseva, Aglaya G. Iyevleva, Ekatherina Sh. Kuligina, Evgeny N. Imyanitov

Publikováno v: Cancer Medicine, Vol 11, Iss 17, Pp 3226-3237 (2022)

Abstract Background Despite the progress in the development of next‐generation sequencing (NGS), diagnostic PCR assays remain to be utilized in clinical routine due to their simplicity and low cost. Tests for 5′‐/3′‐end mRNA unbalanced expr

Externí odkaz: https://doaj.org/article/d38a620319e847078e9a0ddad75d9206

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Akademický článek

Сoronavirus Pandemic and Expert Knowledge Crisis: Reload of Miracle, Mystery and Authority

Autor: Victor Martianov, Victor Rudenko, Leonid Fishman

Publikováno v: Журнал институциональных исследований, Vol 14, Iss 2, Pp 047-058 (2022)

The article analyzes the reasons for the important effect of the COVID-19 pandemic, which has become the catalyst for long-overdue decline in the authority of expert knowledge. The author claims that widespread access to information and scientific da

Externí odkaz: https://doaj.org/article/8db806abe1b249799e96fe0627d12d9c

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Akademický článek

Getting off to a good start

Autor: Igor Martianov, Irwin Davidson

Publikováno v: eLife, Vol 12 (2023)

RNA polymerase II transcription can efficiently occur when mouse embryonic stem cells lack TBP and TBP-like proteins, confirming that this initiation factor may not be as essential as once thought.

Externí odkaz: https://doaj.org/article/df6723229fec41d6b378c9b8b1a2ea2a

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Akademický článek

Molecular genetic testing in colon cancer: clinical aspects

Autor: Aleksandr S. Martianov, Ekaterina Sh. Kuligina, Alexandr A. Romanko, Evgeny N. Imyanitov

Publikováno v: Alʹmanah Kliničeskoj Mediciny, Vol 50, Iss 1, Pp 1-12 (2022)

Molecular genetic diagnostics is an essential element to plan for management of colorectal cancer (CRC) patients. The choice of systemic treatment for CRC is impossible without molecular testing of the tumor. For instance, the assessment of the KRAS

Externí odkaz: https://doaj.org/article/848babb684154534b767c29709cb518b

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Akademický článek

Molecular Analysis of Biliary Tract Cancers with the Custom 3′ RACE-Based NGS Panel

Autor: Natalia V. Mitiushkina, Vladislav I. Tiurin, Aleksandra A. Anuskina, Natalia A. Bordovskaya, Anna D. Shestakova, Aleksandr S. Martianov, Mikhail G. Bubnov, Anna S. Shishkina, Maria V. Semina, Aleksandr A. Romanko, Ekaterina S. Kuligina, Evgeny N. Imyanitov

Publikováno v: Diagnostics, Vol 13, Iss 20, p 3168 (2023)

The technique 3’ rapid amplification of cDNA ends (3′ RACE) allows for detection of translocations with unknown gene partners located at the 3′ end of the chimeric transcript. We composed a 3′ RACE-based RNA sequencing panel for the analysis

Externí odkaz: https://doaj.org/article/782e8f16190b45139d66ab150f76e380

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Akademický článek

Content of circulating tumor DNA depends on the tumor type and the dynamics of tumor size, but is not influenced significantly by physical exercise, time of the day or recent meal

Autor: Kuligina, Ekaterina S., Meerovich, Roman, Zagorodnev, Kirill A., Kholmatov, Maxim M., Sokolova, Tatyana N., Laidus, Tatiana A., Romanko, Aleksandr A., Martianov, Aleksandr S., Anisimova, Maria O., Zaitseva, Olga A., Yatsuk, Olga S., Yanus, Grigoriy A., Imyanitov, Evgeny N.

Publikováno v: In Cancer Genetics August 2021 256-257:165-178

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Akademický článek

Single cell transcriptomics reveal trans-differentiation of pancreatic beta cells following inactivation of the TFIID subunit Taf4

Autor: Thomas Kleiber, Guillaume Davidson, Gabrielle Mengus, Igor Martianov, Irwin Davidson

Publikováno v: Cell Death and Disease, Vol 12, Iss 8, Pp 1-12 (2021)

Abstract Regulation of gene expression involves a complex and dynamic dialogue between transcription factors, chromatin remodelling and modification complexes and the basal transcription machinery. To address the function of the Taf4 subunit of gener

Externí odkaz: https://doaj.org/article/71ad86db7c3945d2ac2b31c5e760e791

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