Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Martial Hervy"'
Autor:
Martial Hervy, Jennifer L Weber, Marylene Pecheul, Paula Dolley-Sonneville, David Henry, Yue Zhou, Zara Melkoumian
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e92120 (2014)
Human mesenchymal stem cells (hMSCs) present an attractive target for cell therapy given their wide availability, immunomodulatory properties, and multipotent nature for differentiation into chondrocytes, osteocytes, and adipocytes. With the progress
Externí odkaz:
https://doaj.org/article/a49f377b35ca47bfb272a30c3de2aad7
Publikováno v:
Open Journal of Biophysics. :222-231
We propose a mathematical model to suggest a unified explanation behind the observation that some cell types tend to spread more efficiently on stiff substrates and are able to adapt their internal stiffness to the external stiffness. Our model also
Autor:
Martial Hervy
Publikováno v:
Journal of Adhesion Science and Technology. 24:963-973
The mechanical balance maintained between the cell and its environment forms the basis of tissue formation, cohesion and homeostasis. Cells are able to sense the mechanical characteristics of the extracellular medium and to modulate their function ac
Autor:
Jean-Pierre Vigneron, Martial Hervy, Claude Degott, Dominique Cazals, Yves A. DeClerck, David Pericat, Christian Auclair, Sylvie Dubois, Phuong-Lan Tran
Publikováno v:
Cancer Gene Therapy. 10:435-444
Metalloproteinases (MMPs) and their natural inhibitors (TIMPs) contribute to the regulation of tumor microenvironment. Their expressions are deregulated in almost all human cancers. We report a novel approach to gene therapy of hepatocellular carcino
Autor:
Elizabeth Marangoni, Jean-François Mouscadet, Martial Hervy, Sabine Vaganay, Jean Bourhis, Frédéric Subra, Laurence Jeanson
Publikováno v:
Virology. 300(1):100-108
To gain new insights regarding the role of Ku, the DNA-PK DNA-binding component, during lentiviral DNA integration, we have investigated the HIV-1 replication in Ku80-depleted human cells. CEM4fx cells underexpressing the Ku80 factor were selected af
Publikováno v:
Biophysical Journal. 112:272a
Polystyrene(PS) is a commonly used material for designing cell culture surfaces like assay plates, petridishes, T flasks to name a few. These surfaces when used for the culture of adherent cells will modulate cell growth and function depending of the
Autor:
Zara Melkoumian, Martial Hervy, David Henry, Yue Zhou, Paula Dolley-Sonneville, Marylene D. M. Pecheul, Jennifer L. Weber
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e92120 (2014)
PLoS ONE
PLoS ONE
Human mesenchymal stem cells (hMSCs) present an attractive target for cell therapy given their wide availability, immunomodulatory properties, and multipotent nature for differentiation into chondrocytes, osteocytes, and adipocytes. With the progress
Publikováno v:
Biophysical Journal. 102(3)
It is known that various cell types can sense and respond to the mechanical properties of their microenvironment. Specifically, cells have been known to spread more when cultured on stiff substrates and are able to match their internal stiffness to t
Publikováno v:
Genescancer. 1(5)
Zyxin is a dual-function LIM domain protein that regulates actin dynamics in response to mechanical stress and shuttles between focal adhesions and the cell nucleus. Here we show that zyxin contributes to UV-induced apoptosis. Exposure of wild-type f
Publikováno v:
Current opinion in cell biology. 18(5)
Cell substratum adhesion influences a variety of processes including motility, proliferation and survival. In recent years, it has become clear that there are proteins that are capable of shuttling between cell adhesion zones and the nucleus, providi