Zobrazeno 1 - 10
of 151
pro vyhledávání: '"Martial, Ruat"'
Autor:
Alice Del Giovane, Mariagiovanna Russo, Linda Tirou, Hélène Faure, Martial Ruat, Sonia Balestri, Carola Sposato, Francesco Basoli, Alberto Rainer, Abdelmoumen Kassoussi, Elisabeth Traiffort, Antonella Ragnini-Wilson
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 15 (2022)
The regeneration of myelin is known to restore axonal conduction velocity after a demyelinating event. Remyelination failure in the central nervous system contributes to the severity and progression of demyelinating diseases such as multiple sclerosi
Externí odkaz:
https://doaj.org/article/b94c9bb02a0440a59c835c7449e23bcd
Autor:
Linda Tirou, Mariagiovanna Russo, Helene Faure, Giuliana Pellegrino, Clement Demongin, Mathieu Daynac, Ariane Sharif, Jeremy Amosse, Soazig Le Lay, Raphaël Denis, Serge Luquet, Mohammed Taouis, Yacir Benomar, Martial Ruat
Publikováno v:
Molecular Metabolism, Vol 47, Iss , Pp 101172- (2021)
Objective: Astrocytes are glial cells proposed as the main Sonic hedgehog (Shh)-responsive cells in the adult brain. Their roles in mediating Shh functions are still poorly understood. In the hypothalamus, astrocytes support neuronal circuits implica
Externí odkaz:
https://doaj.org/article/36a5cf314e1f4588a345c3a8a8257595
Autor:
Linda Tirou, Mariagiovanna Russo, Helene Faure, Giuliana Pellegrino, Ariane Sharif, Martial Ruat
Publikováno v:
PLoS ONE, Vol 15, Iss 2, p e0229362 (2020)
In the mature rodent brain, Sonic Hedgehog (Shh) signaling regulates stem and progenitor cell maintenance, neuronal and glial circuitry and brain repair. However, the sources and distribution of Shh mediating these effects are still poorly characteri
Externí odkaz:
https://doaj.org/article/2edd9337aea34ea0a7a7123f4683f6e7
Autor:
Mathieu Daynac, Linda Tirou, Hélène Faure, Marc-André Mouthon, Laurent R. Gauthier, Heidi Hahn, François D. Boussin, Martial Ruat
Publikováno v:
Stem Cell Reports, Vol 7, Iss 4, Pp 735-748 (2016)
Identifying the mechanisms controlling quiescence and activation of neural stem cells (NSCs) is crucial for understanding brain repair. Here, we demonstrate that Hedgehog (Hh) signaling actively regulates different pools of quiescent and proliferativ
Externí odkaz:
https://doaj.org/article/27a6e426bd4940a6a9431b0a9d15ec0e
Autor:
Julien Ferent, Loïc Cochard, Hélène Faure, Maurizio Taddei, Heidi Hahn, Martial Ruat, Elisabeth Traiffort
Publikováno v:
Stem Cell Reports, Vol 3, Iss 2, Pp 312-323 (2014)
In the adult brain, self-renewal is essential for the persistence of neural stem cells (NSCs) throughout life, but its regulation is still poorly understood. One NSC can give birth to two NSCs or one NSC and one transient progenitor. A correct balanc
Externí odkaz:
https://doaj.org/article/b071b95047814f7187ff97364fd1f161
Autor:
Alessandra Chiarenza, Fabrizio Manetti, Elena Petricci, Martial Ruat, Antonella Naldini, Maurizio Taddei, Fabio Carraro
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0149919 (2016)
The most relevant therapeutic approaches to treat CML rely on the administration of tyrosine kinase inhibitors (TKIs) like Imatinib, which are able to counteract the activity of Bcr-Abl protein increasing patient's life expectancy and survival. Unfor
Externí odkaz:
https://doaj.org/article/1dbd6aad2a8848e7aaef171c651d7254
Autor:
Yannick Gache, Florence Brellier, Sophie Rouanet, Sahar Al-Qaraghuli, Maria Goncalves-Maia, Elodie Burty-Valin, Stéphanie Barnay, Sabine Scarzello, Martial Ruat, Nicolas Sevenet, Marie-Françoise Avril, Thierry Magnaldo
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0145369 (2015)
Basal cell carcinoma (BCC) is the commonest tumor in human. About 70% sporadic BCCs bear somatic mutations in the PATCHED1 tumor suppressor gene which encodes the receptor for the Sonic Hedgehog morphogen (SHH). PATCHED1 germinal mutations are associ
Externí odkaz:
https://doaj.org/article/2c101475a48143828b551b89d6fc30d4
Autor:
Martial Ruat, Ariane Sharif, Mathieu Daynac, Yacir Benomar, Serge Luquet, Soazig Le Lay, Linda Tirou, Mohammed Taouis, Clement Demongin, Jérémy Amosse, Mariagiovanna Russo, Raphael G. P. Denis, Giuliana Pellegrino, Hélène Faure
Publikováno v:
Molecular Metabolism
Molecular metabolism
Molecular metabolism, Elsevier, 2021, 47, pp.101172. ⟨10.1016/j.molmet.2021.101172⟩
Molecular metabolism, Elsevier, 2021, pp.101172. ⟨10.1016/j.molmet.2021.101172⟩
Molecular metabolism, 2021, 47, pp.101172. ⟨10.1016/j.molmet.2021.101172⟩
Molecular Metabolism, Vol 47, Iss, Pp 101172-(2021)
Molecular metabolism
Molecular metabolism, Elsevier, 2021, 47, pp.101172. ⟨10.1016/j.molmet.2021.101172⟩
Molecular metabolism, Elsevier, 2021, pp.101172. ⟨10.1016/j.molmet.2021.101172⟩
Molecular metabolism, 2021, 47, pp.101172. ⟨10.1016/j.molmet.2021.101172⟩
Molecular Metabolism, Vol 47, Iss, Pp 101172-(2021)
Objective Astrocytes are glial cells proposed as the main Sonic hedgehog (Shh)-responsive cells in the adult brain. Their roles in mediating Shh functions are still poorly understood. In the hypothalamus, astrocytes support neuronal circuits implicat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11fb5ff972201183f9a6e9a8ee475cd0
https://pubmed.ncbi.nlm.nih.gov/33513436
https://pubmed.ncbi.nlm.nih.gov/33513436
Autor:
Martial Ruat, Hélène Faure, Linda Tirou, Mariagiovanna Russo, Ariane Sharif, Giuliana Pellegrino
Publikováno v:
PLoS ONE
PLoS ONE, Public Library of Science, 2020, 15 (2), pp.e0229362. ⟨10.1371/journal.pone.0229362⟩
PLoS ONE, 2020, 15 (2), pp.e0229362. ⟨10.1371/journal.pone.0229362⟩
PLoS ONE, Vol 15, Iss 2, p e0229362 (2020)
PLoS ONE, Public Library of Science, 2020, 15 (2), pp.e0229362. ⟨10.1371/journal.pone.0229362⟩
PLoS ONE, 2020, 15 (2), pp.e0229362. ⟨10.1371/journal.pone.0229362⟩
PLoS ONE, Vol 15, Iss 2, p e0229362 (2020)
International audience; In the mature rodent brain, Sonic Hedgehog (Shh) signaling regulates stem and progenitor cell maintenance, neuronal and glial circuitry and brain repair. However, the sources and distribution of Shh mediating these effects are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::178e90f86fce3021a28ee9c5095b471a
https://www.hal.inserm.fr/inserm-02492142/document
https://www.hal.inserm.fr/inserm-02492142/document
Autor:
Wei Xiong, Tao Liu, Yeshi Wang, Xiaowei Chen, Lei Sun, Ning Guo, Hui Zheng, Lianghong Zheng, Martial Ruat, Weiping Han, Claire Xi Zhang, Zhuan Zhou
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e24573 (2011)
AIM: Neurotransmitter release is elicited by an elevation of intracellular Ca(2+) concentration ([Ca(2+)](i)). The action potential triggers Ca(2+) influx through Ca(2+) channels which causes local changes of [Ca(2+)](i) for vesicle release. However,
Externí odkaz:
https://doaj.org/article/566ac8c9e37b43e1ae677a1c60d70953