Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Marti Roses"'
Publikováno v:
Molecules
Volume 28
Issue 3
Pages: 1372
Volume 28
Issue 3
Pages: 1372
Common methods for hold-up time and volume determination in Reversed-Phase Liquid Chromatography (RPLC) have been tested for Hydrophilic Interaction Liquid Chromatography (HILIC). A zwitterionic ZIC-HILIC column has been used for the testing. The pyc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4fd10fa8f114a1c12bd718e230c9211
http://hdl.handle.net/2445/194593
http://hdl.handle.net/2445/194593
Autor:
Elisabet Fuguet, Martí Rosés
Publikováno v:
Journal of Chromatography Open, Vol 6, Iss , Pp 100189- (2024)
The accurate emulation of biological partition systems through physicochemical models is crucial in pharmacology, toxicology, and environmental science for understanding the ADMET profiles of substances. Direct experimentation on biological systems c
Externí odkaz:
https://doaj.org/article/cf4792c3fbe147ef9bea0a298f8e5d4f
Publikováno v:
Advances in Sample Preparation, Vol 6, Iss , Pp 100063- (2023)
In this work, the characterization of several reversed-phase and HILIC chromatographic systems is presented by means of the Abraham's solvation parameter model, focusing on the impact of solute polarizability, dipolarity, hydrogen bonding, and molecu
Externí odkaz:
https://doaj.org/article/a0695aca80af424ca59e40a3c6dc85b1
Publikováno v:
Journal of Chromatography A. 1138:203-215
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::74c350d08a039a4811d1e9bf0bf59483
https://doi.org/10.1016/j.chroma.2006.10.087
https://doi.org/10.1016/j.chroma.2006.10.087
Publikováno v:
Journal of Medicinal Chemistry. 49:4861-4870
Chromatographic retention measurement in immobilized artificial membranes (IAMs) is considered a fast and reliable method to predict biological properties (drug distribution) because of the IAM structure, which consists of phospholipid analogues bond
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d0b4ab6c9134d8f3ca2c8bb3b37c925
https://doi.org/10.1021/jm0602108
https://doi.org/10.1021/jm0602108
Publikováno v:
Membranes, Vol 13, Iss 7, p 640 (2023)
Two parallel artificial membrane permeability assay (PAMPA) systems intended for emulating skin permeability have been characterized through the solvation parameter model of Abraham using multilinear regression analysis. The coefficients of the obtai
Externí odkaz:
https://doaj.org/article/db960de6c55745e8962bf67e9ce3b2f7
Autor:
Alejandro Fernández-Pumarega, Belén Martín-Sanz, Susana Amézqueta, Elisabet Fuguet, Martí Rosés
Publikováno v:
ADMET and DMPK, Vol 8, Iss 1, Pp 98-112 (2020)
The octanol-water partition coefficient (Po/w), or the octanol-water distribution coefficient (Do/w) for ionized compounds, is a key parameter in the drug development process. In a previous work, this parameter was estimated through the retention fac
Externí odkaz:
https://doaj.org/article/c18be40b5ff541f7bd4beaa852e16a95
Publikováno v:
ADMET and DMPK, Vol 8, Iss 1, Pp 16-28 (2020)
In recent years, the parallel artificial membrane permeability assay (PAMPA) has been extended for prediction of skin permeation by developing an artificial membrane which mimics the stratum corneum structure, skin-PAMPA. In the present work, the dif
Externí odkaz:
https://doaj.org/article/d8320ae249354f58ba92808de82ac744
Publikováno v:
Molecules, Vol 28, Iss 3, p 1372 (2023)
Common methods for hold-up time and volume determination in Reversed-Phase Liquid Chromatography (RPLC) have been tested for Hydrophilic Interaction Liquid Chromatography (HILIC). A zwitterionic ZIC-HILIC column has been used for the testing. The pyc
Externí odkaz:
https://doaj.org/article/4601e1018c8a443d95c06c3f2dce56ba
Publikováno v:
ADMET and DMPK, Vol 6, Iss 2, Pp 140-152 (2018)
Dermal absorption is a key process in the drug delivery studies of the pharmaceutical and cosmetic industries, as well as in the fields of dermal toxicology, risk assessment, and the exposure of environmental pollutants. This process is typically des
Externí odkaz:
https://doaj.org/article/54ca671c56104f2f8c9bc6b7dc89e15b