Zobrazeno 1 - 10
of 291
pro vyhledávání: '"Marti, Jett"'
Publikováno v:
Machine Learning and Knowledge Extraction, Vol 6, Iss 1, Pp 699-735 (2024)
In this review, we compiled convolutional neural network (CNN) methods which have the potential to automate the manual, costly and error-prone processing of medical images. We attempted to provide a thorough survey of improved architectures, popular
Externí odkaz:
https://doaj.org/article/2a732a765d5e40f19eb48ab3a0139191
Autor:
Reinhard Laubenbacher, Fred Adler, Gary An, Filippo Castiglione, Stephen Eubank, Luis L. Fonseca, James Glazier, Tomas Helikar, Marti Jett-Tilton, Denise Kirschner, Paul Macklin, Borna Mehrad, Beth Moore, Virginia Pasour, Ilya Shmulevich, Amber Smith, Isabel Voigt, Thomas E. Yankeelov, Tjalf Ziemssen
Publikováno v:
npj Systems Biology and Applications, Vol 10, Iss 1, Pp 1-8 (2024)
Abstract Medical digital twins are computational models of human biology relevant to a given medical condition, which are tailored to an individual patient, thereby predicting the course of disease and individualized treatments, an important goal of
Externí odkaz:
https://doaj.org/article/c741c1f590ac45d283f64aef08c6b4cb
Autor:
Zachary N. Blalock, Gwyneth W. Y Wu, Daniel Lindqvist, Caroline Trumpff, Janine D. Flory, Jue Lin, Victor I. Reus, Ryan Rampersaud, Rasha Hammamieh, Aarti Gautam, SBPBC, Francis J. Doyle, Charles R. Marmar, Marti Jett, Rachel Yehuda, Owen M. Wolkowitz, Synthia H. Mellon
Publikováno v:
Translational Psychiatry, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Circulating cell-free mitochondrial DNA (ccf-mtDNA) is a biomarker of cellular injury or cellular stress and is a potential novel biomarker of psychological stress and of various brain, somatic, and psychiatric disorders. No studies have yet
Externí odkaz:
https://doaj.org/article/462b504a442545f2add418e35eab0665
Autor:
Reinhard Laubenbacher, Fred Adler, Gary An, Filippo Castiglione, Stephen Eubank, Luis L. Fonseca, James Glazier, Tomas Helikar, Marti Jett-Tilton, Denise Kirschner, Paul Macklin, Borna Mehrad, Beth Moore, Virginia Pasour, Ilya Shmulevich, Amber Smith, Isabel Voigt, Thomas E. Yankeelov, Tjalf Ziemssen
Publikováno v:
Frontiers in Digital Health, Vol 6 (2024)
A fundamental challenge for personalized medicine is to capture enough of the complexity of an individual patient to determine an optimal way to keep them healthy or restore their health. This will require personalized computational models of suffici
Externí odkaz:
https://doaj.org/article/33cfd1e3513942e8b5e508835b666174
Autor:
Ryan Rampersaud, Ekaterina Protsenko, Ruoting Yang, Victor Reus, Rasha Hammamieh, Gwyneth W. Y. Wu, Elissa Epel, Marti Jett, Aarti Gautam, Synthia H. Mellon, Owen M. Wolkowitz
Publikováno v:
Translational Psychiatry, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract Adverse childhood experiences have been consistently linked with physical and mental health disorders in adulthood that may be mediated, in part, via the effects of such exposures on biological aging. Using recently developed “epigenetic c
Externí odkaz:
https://doaj.org/article/f221bc9ea6514ef5816e1a754594afdb
Autor:
Abdulnaser Alkhalil, John Clifford, Stacyann M. Miller, Aarti Gautam, Marti Jett, Rasha Hammamieh, Lauren T. Moffatt, Jeffrey W. Shupp
Publikováno v:
Current Issues in Molecular Biology, Vol 44, Iss 8, Pp 3711-3734 (2022)
Countermeasures for radiation diagnosis, prognosis, and treatment are trailing behind the proliferation of nuclear energy and weaponry. Radiation injury mechanisms at the systems biology level are not fully understood. Here, mice skin biopsies at h2,
Externí odkaz:
https://doaj.org/article/3291aab9eaaf441bb4b63b532874e3be
Autor:
Ruoting Yang, Changxin Xu, Linda M. Bierer, Janine D. Flory, Aarti Gautam, Heather N. Bader, Amy Lehrner, Iouri Makotkine, Frank Desarnaud, Stacy A. Miller, Marti Jett, Rasha Hammamieh, Rachel Yehuda
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-7 (2021)
Abstract Epigenetic changes are currently invoked as explanations for both the chronicity and tenacity of post-traumatic stress disorder (PTSD), a heterogeneous condition showing varying, sometimes idiosyncratic responses to treatment. This study eva
Externí odkaz:
https://doaj.org/article/608b3b341c9d492788efb76b24a8c8c7
Autor:
Ekaterina Protsenko, Ruoting Yang, Brent Nier, Victor Reus, Rasha Hammamieh, Ryan Rampersaud, Gwyneth W. Y. Wu, Christina M. Hough, Elissa Epel, Aric A. Prather, Marti Jett, Aarti Gautam, Synthia H. Mellon, Owen M. Wolkowitz
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Major depressive disorder (MDD) is associated with premature mortality and is an independent risk factor for a broad range of diseases, especially those associated with aging, such as cardiovascular disease, diabetes, and Alzheimer’s disea
Externí odkaz:
https://doaj.org/article/1ed1f36ac858446c87cd14a337d98223
Autor:
Carole E. Siegel, Eugene M. Laska, Ziqiang Lin, Mu Xu, Duna Abu-Amara, Michelle K. Jeffers, Meng Qian, Nicholas Milton, Janine D. Flory, Rasha Hammamieh, Bernie J. Daigle, Aarti Gautam, Kelsey R. Dean, Victor I. Reus, Owen M. Wolkowitz, Synthia H. Mellon, Kerry J. Ressler, Rachel Yehuda, Kai Wang, Leroy Hood, Francis J. Doyle, Marti Jett, Charles R. Marmar
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract We sought to find clinical subtypes of posttraumatic stress disorder (PTSD) in veterans 6–10 years post-trauma exposure based on current symptom assessments and to examine whether blood biomarkers could differentiate them. Samples were mal
Externí odkaz:
https://doaj.org/article/e49caa92c9774a64b4ce6cfdf977ed9d
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
The association between the shift in fecal resident microbiome and social conflicts with long-term consequences on psychological plasticity, such as the development of post-traumatic stress disorder (PTSD), is yet to be comprehended. We developed an
Externí odkaz:
https://doaj.org/article/6abb2cb1c93d4cadada87e5d17eaae9c