Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Marthe M. de Jonge"'
Autor:
Lise M. van Wijk, Claire J. H. Kramer, Sylvia Vermeulen, Natalja T. ter Haar, Marthe M. de Jonge, Judith R. Kroep, Cor D. de Kroon, Katja N. Gaarenstroom, Harry Vrieling, Tjalling Bosse, Maaike P. G. Vreeswijk
Publikováno v:
Cancers, Vol 13, Iss 12, p 2994 (2021)
PARP inhibitor (PARPi) sensitivity is related to tumor-specific defects in homologous recombination (HR). Therefore, there is great clinical interest in tests that can rapidly and reliably identify HR deficiency (HRD). Functional HRD tests determine
Externí odkaz:
https://doaj.org/article/5c7e5eef71a44a0eac94c873b0137992
The RECAP Test Rapidly and Reliably Identifies Homologous Recombination-Deficient Ovarian Carcinomas
Autor:
Lise M. van Wijk, Sylvia Vermeulen, Matty Meijers, Manuela F. van Diest, Natalja T. ter Haar, Marthe M. de Jonge, Nienke Solleveld-Westerink, Tom van Wezel, Dik C. van Gent, Judith R. Kroep, Tjalling Bosse, Katja N. Gaarenstroom, Harry Vrieling, Maaike P. G. Vreeswijk
Publikováno v:
Cancers, Vol 12, Iss 10, p 2805 (2020)
Recent studies have shown that the efficacy of PARP inhibitors in epithelial ovarian carcinoma (EOC) is related to tumor-specific defects in homologous recombination (HR) and extends beyond BRCA1/2 deficient EOC. A robust method with which to identif
Externí odkaz:
https://doaj.org/article/330d37fda87941d7988c9f7ebb46b4ce
Autor:
Tjalling Bosse, Brooke E. Howitt, Vincent T.H.B.M. Smit, Flora E. van Leeuwen, Christi J. van Asperen, Matti A. Rookus, Harry Hollema, Rutika Puranik, Jeremy P. Segal, Maaike P.G. Vreeswijk, Cornelis D. de Kroon, Lauren L. Ritterhouse, Marthe M. de Jonge
Class 4/5 mutations and Tumor Mutational Burden stratified by loss of heterozygosity status.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b6554e3d74b2a412bff760bc43f3ef6
https://doi.org/10.1158/1078-0432.22471688.v1
https://doi.org/10.1158/1078-0432.22471688.v1
Autor:
Tjalling Bosse, Brooke E. Howitt, Vincent T.H.B.M. Smit, Flora E. van Leeuwen, Christi J. van Asperen, Matti A. Rookus, Harry Hollema, Rutika Puranik, Jeremy P. Segal, Maaike P.G. Vreeswijk, Cornelis D. de Kroon, Lauren L. Ritterhouse, Marthe M. de Jonge
Germline BRCA1/2 Mutations and Variant Allele Frequencies detected in the FFPE-isolated tumor DNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::655b5ef24d6d98e1df3215e63f754e88
https://doi.org/10.1158/1078-0432.22471679.v1
https://doi.org/10.1158/1078-0432.22471679.v1
Autor:
Tjalling Bosse, Brooke E. Howitt, Vincent T.H.B.M. Smit, Flora E. van Leeuwen, Christi J. van Asperen, Matti A. Rookus, Harry Hollema, Rutika Puranik, Jeremy P. Segal, Maaike P.G. Vreeswijk, Cornelis D. de Kroon, Lauren L. Ritterhouse, Marthe M. de Jonge
Purpose:Whether endometrial carcinoma (EC) should be considered part of the gBRCA1/2-associated hereditary breast and ovarian cancer (HBOC) syndrome is topic of debate. We sought to assess whether ECs occurring in gBRCA carriers are enriched for clin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2abbf9306faf63e830bdd8b26ecb3cd7
https://doi.org/10.1158/1078-0432.c.6527963.v1
https://doi.org/10.1158/1078-0432.c.6527963.v1
Autor:
Tjalling Bosse, Maaike P.G. Vreeswijk, Alexandra Leary, Etienne Rouleau, Cor D. de Kroon, Yannick Boursin, Bastien Job, Harry Vrieling, David N. Church, Mark A. Glaire, Remi A. Nout, Vincent T.H.B.M. Smit, Natalja T. ter Haar, Matty Meijers, Philip C. Schouten, Lise M. van Wijk, Aurélie Auguste, Marthe M. de Jonge
Supplementary Material and Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17d9d1e6d547375ed6a6fe0b5b87a231
https://doi.org/10.1158/1078-0432.22468142
https://doi.org/10.1158/1078-0432.22468142
Autor:
Tjalling Bosse, Maaike P.G. Vreeswijk, Alexandra Leary, Etienne Rouleau, Cor D. de Kroon, Yannick Boursin, Bastien Job, Harry Vrieling, David N. Church, Mark A. Glaire, Remi A. Nout, Vincent T.H.B.M. Smit, Natalja T. ter Haar, Matty Meijers, Philip C. Schouten, Lise M. van Wijk, Aurélie Auguste, Marthe M. de Jonge
Purpose:The elevated levels of somatic copy-number alterations (SCNAs) in a subset of high-risk endometrial cancers are suggestive of defects in pathways governing genome integrity. We sought to assess the prevalence of homologous recombination defic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dff2fda19256b3d5f75f17c7ebe98757
https://doi.org/10.1158/1078-0432.c.6526850.v1
https://doi.org/10.1158/1078-0432.c.6526850.v1
Autor:
Tjalling Bosse, Maaike P.G. Vreeswijk, Alexandra Leary, Etienne Rouleau, Cor D. de Kroon, Yannick Boursin, Bastien Job, Harry Vrieling, David N. Church, Mark A. Glaire, Remi A. Nout, Vincent T.H.B.M. Smit, Natalja T. ter Haar, Matty Meijers, Philip C. Schouten, Lise M. van Wijk, Aurélie Auguste, Marthe M. de Jonge
Figure S1 shows that the Oncoscan and CGH agilent platform yield similar results.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a0c87cfd751bf45c1d1b144c1ed9b57
https://doi.org/10.1158/1078-0432.22468148
https://doi.org/10.1158/1078-0432.22468148
Autor:
Tjalling Bosse, Maaike P.G. Vreeswijk, Alexandra Leary, Etienne Rouleau, Cor D. de Kroon, Yannick Boursin, Bastien Job, Harry Vrieling, David N. Church, Mark A. Glaire, Remi A. Nout, Vincent T.H.B.M. Smit, Natalja T. ter Haar, Matty Meijers, Philip C. Schouten, Lise M. van Wijk, Aurélie Auguste, Marthe M. de Jonge
Table S1 shows the clinicopathological characteristics of the cases included in final analysis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::478ebbf175a1a412e395f325e3a52f47
https://doi.org/10.1158/1078-0432.22468139.v1
https://doi.org/10.1158/1078-0432.22468139.v1
Autor:
Tjalling Bosse, Brooke E. Howitt, Vincent T.H.B.M. Smit, Flora E. van Leeuwen, Christi J. van Asperen, Matti A. Rookus, Harry Hollema, Rutika Puranik, Jeremy P. Segal, Maaike P.G. Vreeswijk, Cornelis D. de Kroon, Lauren L. Ritterhouse, Marthe M. de Jonge
Supplementary Material and Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0e57c2ec183c18a91be3f5ba5fd4510
https://doi.org/10.1158/1078-0432.22471685
https://doi.org/10.1158/1078-0432.22471685