Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Martha Robles-Flores"'
Autor:
Miguel Angel Sarabia-Sánchez, Angela Patricia Moreno-Londoño, María Cristina Castañeda-Patlán, Eduardo Alvarado-Ortiz, Juan Carlos Martínez-Morales, Martha Robles-Flores
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
IntroductionCancer Stem Cells (CSC) are responsible for maintaining tumor growth, chemoresistance, and metastasis. Therefore, understanding their characteristics is critical to progress in cancer therapy. While the contribution of the canonical Wnt/b
Externí odkaz:
https://doaj.org/article/e70f4ea51f46417b8da1947b0128a988
Autor:
Victoria Jiménez-Castillo, Daniela Illescas-Barbosa, Edgar Zenteno, Beatriz Xóchitl Ávila-Curiel, Maria Cristina Castañeda-Patlán, Martha Robles-Flores, Daniel Montante-Montes De Oca, Eduardo Pérez-Campos, Anayetzin Torres-Rivera, Abdelouhab Bouaboud, Patrick Pagesy, Carlos Josué Solórzano-Mata, Tarik Issad
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract O-linked β-N-acetylglucosaminylation (O-GlcNAcylation) is a reversible post-translational modification on serine and threonine residues of cytosolic, nuclear and mitochondrial proteins. O-GlcNAcylation level is regulated by OGT (O-GlcNAc tr
Externí odkaz:
https://doaj.org/article/5e0dde4c5d1f4e13a998f05ec6e9eace
Autor:
Abril Saint-Martin, Marco Antonio Morquecho-León, Maria Cristina Castañeda-Patlán, Martha Robles-Flores
Publikováno v:
Biochemistry and Biophysics Reports, Vol 32, Iss , Pp 101336- (2022)
Astrin/SPAG5 is a mitotic spindle protein found to be overexpressed in several human cancers, functioning as an oncogene. The expression of Astrin has not been reported so far in colon cancer, nor has it been related to HIFs expression or action. Sin
Externí odkaz:
https://doaj.org/article/bec31824d09343a983b9c84f2aeddfc4
Autor:
Carlos Alejandro Egusquiza-Alvarez, M. Cristina Castañeda-Patlán, Sara Albarran-Gutierrez, Héctor Gonzalez-Aguilar, Angela P. Moreno-Londoño, Vilma Maldonado, Jorge Melendez-Zajgla, Martha Robles-Flores
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
p32 is a multifunctional and multicompartmental protein that has been found upregulated in numerous adenocarcinomas, including colorectal malignancy. High levels of p32 expression have been correlated with poor prognosis in colorectal cancer. However
Externí odkaz:
https://doaj.org/article/eb695909bce6402a82e2a3308f8ddd7e
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
Cancer cells characteristically have a high proliferation rate. Because tumor growth depends on energy-consuming anabolic processes, including biosynthesis of protein, lipid, and nucleotides, many tumor-associated conditions, including intermittent o
Externí odkaz:
https://doaj.org/article/a9ff7e4eefd8456188a3cfe2f0e1a4c8
Publikováno v:
Data in Brief, Vol 11, Iss C, Pp 562-566 (2017)
Limb amputation in axolotls was performed to obtain data demonstrating that a chemical agonist of Wnt (int-related protein)/β-catenin signalling can have a role in axolotl limb regeneration (Wischin et al., 2017) [1]. The data revealed that active
Externí odkaz:
https://doaj.org/article/590b7dcca56e4e92ab9c3e3b68ea013b
Autor:
Gabriela Fuentes-García, M. Cristina Castañeda-Patlán, Anne-Sophie Vercoutter-Edouart, Tony Lefebvre, Martha Robles-Flores
Publikováno v:
Frontiers in Endocrinology, Vol 10 (2019)
The dynamic O-linked-N-acetylglucosamine posttranslational modification of nucleocytoplasmic proteins has emerged as a key regulator of diverse cellular processes including several hallmarks of cancer. However, the role played by this modification in
Externí odkaz:
https://doaj.org/article/6d5ec206710b470d8d136c27c3b549af
Autor:
Paula Santoyo-Ramos, María Likhatcheva, Eduardo A García-Zepeda, M Cristina Castañeda-Patlán, Martha Robles-Flores
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e112580 (2014)
This study examined the role played by hypoxia-inducible factors (HIFs) in malignant phenotype maintenance and canonical Wnt signaling. Under normoxia, we determined that both HIF-1α and HIF-2α are expressed in human colon cancer cells but not in t
Externí odkaz:
https://doaj.org/article/539cd29277bb472c846bb3960efa6699
Autor:
José G Hernández-Maqueda, Luis Bernardo Luna-Ulloa, Paula Santoyo-Ramos, M Cristina Castañeda-Patlán, Martha Robles-Flores
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e58540 (2013)
The tumor suppressor Adenomatous Polyposis coli (APC) gene is mutated or lost in most colon cancers. Alterations in Protein kinase C (PKC) isozyme expression and aberrant regulation also comprise early events in intestinal carcinomas. Here we show th
Externí odkaz:
https://doaj.org/article/5727826690094f1b8a1d929de20cda81
Autor:
Angela Patricia Moreno-Londoño, María Cristina Castañeda-Patlán, Miguel Angel Sarabia-Sánchez, Marina Macías-Silva, Martha Robles-Flores
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 6; Pages: 5252
The presence of cancer stem cells (CSCs) has been associated with the induction of drug resistance and disease recurrence after therapy. 5-Fluorouracil (5FU) is widely used as the first-line treatment of colorectal cancer (CRC). However, its effectiv