Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Martha R. Sumler"'
Autor:
Surendra P. Shrivastava, Martha R. Sumler, Michael F. Hughes, Brenda C. Edwards, John H. Goodwin, Larry L. Hall, P. V. Shah, Henry L. Fisher
Publikováno v:
Journal of Toxicology and Environmental Health. 37:57-71
The purpose of this study was to investigate the dermal absorption of chemicals in different physical forms when applied to female F344 rats. Chemicals were applied either as a solid, aqueous paste, suspension, or dissolved in the volatile vehicle et
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26560c5afc3307d4fd2744ab7458209d
https://doi.org/10.1080/15287399209531657
https://doi.org/10.1080/15287399209531657
Publikováno v:
Fundamental and Applied Toxicology. 19:258-267
[ 14 C]Dinoseb was applied to previously clipped back skin of 33- and 82-day-old female Fischer 344 rats at a dosage range of 210–2680 nmol/cm 2 . Radioactivity in the treated skin, tissues, urine, and feces was determined at 1, 6, 24, 48, 72, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::08d81550bc75bdefdf230dcac9e0effe
https://doi.org/10.1016/0272-0590(92)90159-f
https://doi.org/10.1016/0272-0590(92)90159-f
Publikováno v:
Journal of Toxicology and Environmental Health. 36:251-271
Age dependence in dermal absorption has been a major concern in risk assessment. Captan, a chloroalkyl thio heterocyclic fungicide, was selected for study of age dependence as representative of this class of pesticides. Dermal penetration of [14C]cap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aea0c266c488ca4830e8f4a1652924ae
https://doi.org/10.1080/15287399209531636
https://doi.org/10.1080/15287399209531636
Publikováno v:
Toxicological Sciences. 19:258-267
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1c916a1038a3a4ba4642c4720e4c2f1a
https://doi.org/10.1093/toxsci/19.2.258
https://doi.org/10.1093/toxsci/19.2.258
Publikováno v:
Environmental research. 79(2)
The objective of this study was to evaluate the effect of age and dosage on percutaneous absorption and disposition of [14C]chlordecone (Kepone) and to describe results using a physiological based pharmacokinetic (PBPK) model. Female Fischer 344 rats
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93295082ea471062879709adfa9ff01b
https://pubmed.ncbi.nlm.nih.gov/9841813
https://pubmed.ncbi.nlm.nih.gov/9841813
Autor:
Frank Copeland, Robert J. Kavlock, M. Ebron-McCoy, Henry L. Fisher, Larry L. Hall, Brenda C Edwards, S. P. Shrivastava, Martha R. Sumler, Linda A. Oglesby
Publikováno v:
Teratology. 48(4)
The purpose of this study was to examine the toxicokinetics of embryo uptake following exposure to a variety of chemically related phenols in rat embryo culture. The uptake of nine radiolabeled para-substituted phenols by day 10(9–13 somite stage)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a048b4def3a40b6f146787a47c3493ec
https://pubmed.ncbi.nlm.nih.gov/8278928
https://pubmed.ncbi.nlm.nih.gov/8278928
In vivo and in vitro dermal penetration of 2,4,5,2′,4′,5′-Hexachlorobiphenyl in young and adult rats
Publikováno v:
Environmental Research. 50:120-139
Penetration of 2,4,5,2',4',5'-[14C]hexachlorobiphenyl (HCB) through skin of young (33 days) and adult (82 days) female Fischer 344 rats was determined in vivo and by two in vitro methods. In vivo dermal penetration at 120 hr was 45% in young and 43%
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0830da6043f9ee0994415011f016259
https://doi.org/10.1016/s0013-9351(89)80053-2
https://doi.org/10.1016/s0013-9351(89)80053-2
Publikováno v:
Journal of Toxicology and Environmental Health. 22:207-223
Dermal penetration of carbofuran was determined in young (33 d) and adult (82 d) female Fischer 344 rats employing in vivo and in vitro methods. In vivo dermal penetration at 120 h was 43% for young and 18% for adult rats. The half-time for carbofura
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::598f4d84c712dbe1f0f4d0971e01c6b7
https://doi.org/10.1080/15287398709531064
https://doi.org/10.1080/15287398709531064
Publikováno v:
Environmental Research. 47:59-71
Seven-day-old Long Evans rats received one mumol of 203Hg-labeled methyl mercury/kg sc and whole body retention and tissue distribution of organic and inorganic mercury were examined for 32 days postdosing. Neonates cleared mercury slowly until 10 da
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aaad8c350c00602aa2df7cd80dc557bd
https://doi.org/10.1016/s0013-9351(88)80021-5
https://doi.org/10.1016/s0013-9351(88)80021-5
Publikováno v:
Journal of Toxicology and Environmental Health. 15:623-633
Dermal absorption, distribution, and metabolism of 1,3-diphenylguanidine (CAS 102-06-7) (DPG), widely used as an accelerator in processing rubber and in food packaging, was studied in adult female Sprague-Dawley rats. DPG shows 10% penetration throug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5df6c28198253a606af04db8986dde61
https://doi.org/10.1080/15287398509530691
https://doi.org/10.1080/15287398509530691