Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Martha R. Neagu"'
Autor:
Benedito A Carneiro, Kyriakos P Papadopoulos, John H Strickler, Andrew B Lassman, Saiama N Waqar, Young Kwang Chae, Jyoti D Patel, Einat Shacham-Shmueli, Karen Kelly, Mustafa Khasraw, Christine M Bestvina, Ryan Merrell, Kevin Huang, Harisha Atluri, Peter Ansell, Rachel Li, Janet Jin, Mark G Anderson, Edward B Reilly, Gladys Morrison-Thiele, Kalpesh Patel, Randy R Robinson, Martha R Neagu Aristide, Hui K Gan
Publikováno v:
Neuro-Oncology Advances. 5
BackgroundSerclutamab talirine (Ser-T, formerly ABBV-321) is an antibody-drug conjugate consisting of an antibody (AM-1-ABT-806) directed against activated epidermal growth factor receptor (EGFR) and a pyrrolobenzodiazepine dimer. We investigated Ser
Autor:
Meenal Datta, Sampurna Chatterjee, Elizabeth M. Perez, Simon Gritsch, Sylvie Roberge, Mark Duquette, Ivy X. Chen, Kamila Naxerova, Ashwin S. Kumar, Mitrajit Ghosh, Kyrre E. Emblem, Mei R. Ng, William W. Ho, Pragya Kumar, Shanmugarajan Krishnan, Xinyue Dong, Maria C. Speranza, Martha R. Neagu, David A. Reardon, Arlene H. Sharpe, Gordon J. Freeman, Mario L. Suvà, Lei Xu, Rakesh K. Jain
Immune checkpoint blockers (ICBs) have failed in all Phase III glioblastoma trials. Here, we found that ICBs induce cerebral edema in some patients and mice with glioblastoma. Through single-cell RNA sequencing, intravital imaging, and T cell blockin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d6474488349a3ee36820acad414ac747
https://doi.org/10.1101/2022.06.28.497997
https://doi.org/10.1101/2022.06.28.497997
Autor:
Patricia M. LoRusso, Emiliano Calvo Aller, Noboru Yamamoto, Chia-Chi Lin, Thaddeus Beck, David Sommerhalder, Do-Youn Oh, John D. Powderly, Talia Golan, Linu Sara Abraham, Joel S. Hayflick, Tamar Uziel, Priya Brunsdon, Wijith Munasinghe, Marcia Paddock, Cathleen Brdlik Hartman, Jonathan Powell, Bruno Medeiros, Martha R. Neagu, Benedito A. Carneiro
Publikováno v:
Cancer Research. 83:CT257-CT257
Background: Protein tyrosine phosphatase non-receptor type 2 and type 1 (PTPN2/1) antagonists inhibit PTPN2/1-mediated negative regulation of immune response pathways. They may promote antitumor activity by increasing function of immune cells such as
Autor:
Massimo Pizzato, Sean Matthew McCauley, Martha R Neagu, Thomas Pertel, Claudia Firrito, Serena Ziglio, Ann Dauphin, Madeleine Zufferey, Lionel Berthoux, Jeremy Luban
Publikováno v:
PLoS Pathogens, Vol 11, Iss 7, p e1005050 (2015)
HIV-2 and SIVMAC are AIDS-causing, zoonotic lentiviruses that jumped to humans and rhesus macaques, respectively, from SIVSM-bearing sooty mangabey monkeys. Cross-species transmission events such as these sometimes necessitate virus adaptation to spe
Externí odkaz:
https://doaj.org/article/3f328fc1e22549499a88eac23c08ae33
Publikováno v:
Cancer Neurology in Clinical Practice ISBN: 9783319578996
While immune-based cancer therapies are generally more easily tolerated than cytotoxic or targeted therapies, and serious neurological complications occur rarely, they carry their own unique neurological complications. With the increasing use of immu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::842b2401f18ffd2b99f97c9cd1e540e9
https://doi.org/10.1007/978-3-319-57901-6_17
https://doi.org/10.1007/978-3-319-57901-6_17
Autor:
Arlene H. Sharpe, Robert T. Manguso, Martha R. Neagu, John G. Doench, Gordon J. Freeman, Sean E. Lawler, Maria Carmela Speranza, W. Nicholas Haining
Publikováno v:
Neuro-Oncology. 19:vi118-vi118
Autor:
David A. Reardon, Martha R. Neagu
Publikováno v:
Current treatment options in oncology. 16(11)
Existing therapies for glioblastoma (GBM), the most common malignant primary brain tumor in adults, have fallen short of improving the dismal patient outcomes, with an average 14-16-month median overall survival. The biological complexity and adaptab
Autor:
David A. Reardon, Martha R. Neagu
Publikováno v:
Immunotherapy. 7(6)
Glioblastoma (GBM), the most common malignant primary tumor in adults, carries a dismal prognosis. Median overall survival (OS) following currently available standard therapy for newly diagnosed patients, which includes maximal safe resection followe
Publikováno v:
Chinese clinical oncology. 4(2)
Brain metastases (BM) constitute the majority of intracranial cancers and carry with them a dismal prognosis. Several common cancers have a particular predilection for spread to the brain, amongst them lung cancer, breast cancer, melanoma, renal cell
Publikováno v:
Current Infectious Disease Reports. 17
Infections of the nervous system have a significant impact on global mortality and morbidity. These infections are medical emergencies that are frequently diagnostically challenging. Incorporation of neuroimaging can be essential for early diagnosis