Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Martha R, Stark"'
Autor:
Leonard Schärfen, Dagmar Zigackova, Kirsten A. Reimer, Martha R. Stark, Viktor A. Slat, Nancy J. Francoeur, Melissa L. Wells, Lecong Zhou, Perry J. Blackshear, Karla M. Neugebauer, Stephen D. Rader
Publikováno v:
Frontiers in Genetics, Vol 12 (2022)
Alternative polyadenylation (APA) is widespread among metazoans and has been shown to have important impacts on mRNA stability and protein expression. Beyond a handful of well-studied organisms, however, its existence and consequences have not been w
Externí odkaz:
https://doaj.org/article/102645cef62646d1ae3cbf4698f7fb79
Autor:
Leonard, Schärfen, Dagmar, Zigackova, Kirsten A, Reimer, Martha R, Stark, Viktor A, Slat, Nancy J, Francoeur, Melissa L, Wells, Lecong, Zhou, Perry J, Blackshear, Karla M, Neugebauer, Stephen D, Rader
Publikováno v:
Frontiers in genetics. 12
Alternative polyadenylation (APA) is widespread among metazoans and has been shown to have important impacts on mRNA stability and protein expression. Beyond a handful of well-studied organisms, however, its existence and consequences have not been w
Publikováno v:
Journal of Eukaryotic Microbiology. 68
Pre-mRNA splicing is a highly conserved eukaryotic process, but our understanding of it is limited by a historical focus on well-studied organisms such as humans and yeast. There is considerable diversity in mechanisms and components of pre-mRNA spli
Autor:
Naomi M. Fast, Andrew M. MacMillan, Martha R. Stark, T.A. Whelan, Erin L. Garside, Stephen D. Rader
Publikováno v:
Journal of molecular biology. 431(14)
Conformational rearrangements are critical to regulating the assembly and activity of the spliceosome. The spliceosomal protein Prp8 undergoes multiple conformational changes during the course of spliceosome assembly, activation, and catalytic activi
Publikováno v:
RNA Biology
Pre-mRNA splicing has been considered one of the hallmarks of eukaryotes, yet its diversity is astonishing: the number of substrate introns for splicing ranges from hundreds of thousands in humans to a mere handful in certain parasites. The catalytic
Autor:
Anthony R. Daniele, Cameron J. Grisdale, Matthew R. G. Halstead, Elizabeth A. Dunn, William S. C. Dunn, Stephen D. Rader, Naomi M. Fast, Martha R. Stark
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 112(11)
The human spliceosome is a large ribonucleoprotein complex that catalyzes pre-mRNA splicing. It consists of five snRNAs and more than 200 proteins. Because of this complexity, much work has focused on the Saccharomyces cerevisiae spliceosome, viewed
Publikováno v:
RNA. 12:2014-2019
RNA ligation has been a powerful tool for incorporation of cross-linkers and nonnatural nucleotides into internal positions of RNA molecules. The most widely used method for template-directed RNA ligation uses DNA ligase and a DNA splint. While this
Autor:
Martha R, Stark, Stephen D, Rader
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1126
Pre-messenger RNA splicing is a surprisingly complex and dynamic process, the details of which remain largely unknown. One important method for studying splicing involves the replacement of endogenous splicing components with their synthetic counterp
Autor:
Martha R, Stark, Stephen D, Rader
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1126
RNA ligation allows the creation of large RNA molecules from smaller pieces. This can be useful in a number of contexts: to generate molecules that are larger than can be directly synthesized; to incorporate site-specific changes or RNA modifications
Autor:
Stephen D. Rader, Martha R. Stark
Publikováno v:
Methods in Molecular Biology ISBN: 9781627039796
RNA ligation allows the creation of large RNA molecules from smaller pieces. This can be useful in a number of contexts: to generate molecules that are larger than can be directly synthesized; to incorporate site-specific changes or RNA modifications
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6b63ab6f66380dab3d3ab871e5d8d38f
https://doi.org/10.1007/978-1-62703-980-2_10
https://doi.org/10.1007/978-1-62703-980-2_10