Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Martha P Kanjiya"'
Autor:
David E Komatsu, Sardar M Z Uddin, Chris Gordon, Martha P Kanjiya, Diane Bogdan, Justice Achonu, Adriana DiBua, Hira Iftikhar, Amanda Ackermann, Rohan J Shah, Jason Shieh, Agnieszka B Bialkowska, Martin Kaczocha
Publikováno v:
PLoS ONE, Vol 17, Iss 12, p e0278632 (2022)
Total knee arthroplasty (TKA) is the final treatment option for patients with advanced knee osteoarthritis (OA). Unfortunately, TKA surgery is accompanied by acute postoperative pain that is more severe than arthroplasty performed in other joints. El
Externí odkaz:
https://doaj.org/article/50003744588645228d7d4ddd61bbf0de
Autor:
Diane M, Bogdan, Keith, Studholme, Adriana, DiBua, Chris, Gordon, Martha P, Kanjiya, Mei, Yu, Michelino, Puopolo, Martin, Kaczocha
Publikováno v:
Scientific Reports. 12
The endocannabinoid anandamide (AEA) produces antinociceptive effects by activating cannabinoid receptor 1 (CB1). However, AEA also serves as an agonist at transient receptor potential vanilloid receptor 1 (TRPV1) in nociceptive sensory neurons, whic
Autor:
Martin Kaczocha, Justas Lauzadis, Yong Lu, Martha P. Kanjiya, Michelino Puopolo, Maksym Doroshenko, Mario J. Rebecchi
Publikováno v:
The Journal of Neuroscience. 38:8809-8821
The dorsal horn of the spinal cord represents the first relay station in the pain pathway where primary nociceptive inputs are modulated by local circuits and by descending signals before being relayed to supraspinal nuclei. To determine whether dopa
Autor:
Panayotis K. Thanos, Matthew W. Elmes, Roh-Yu Shen, Jeremy T. Miyauchi, Diane Bogdan, Dale G. Deutsch, Samir Haj-Dahmane, Stella E. Tsirka, Keith M. Studholme, Martha P. Kanjiya, Martin Kaczocha
Publikováno v:
Proceedings of the National Academy of Sciences. 115:3482-3487
Endocannabinoids (eCBs) are lipid-signaling molecules involved in the regulation of numerous behaviors and physiological functions. Released by postsynaptic neurons, eCBs mediate retrograde modulation of synaptic transmission and plasticity by activa
Autor:
Yong Lu, Keith M. Studholme, Iwao Ojima, Martin Kaczocha, Jerome Falcone, Diane Bogdan, Martha P. Kanjiya, Su Yan, Maria Adelaida Gomez, Michelino Puopolo, Sang Hoon Park, Gregory Carbonetti, Norbert Smietalo, Matthew W. Elmes
Publikováno v:
The Journal of biological chemistry. 293(14)
Fatty acid–binding proteins (FABPs) are intracellular lipid carriers that regulate inflammation, and pharmacological inhibition of FABP5 reduces inflammation and pain. The mechanism(s) underlying the anti-inflammatory effects associated with FABP5
Publikováno v:
Endocrinology. 154:3251-3260
Sexual receptivity in the female rat is dependent on dose and duration of estradiol exposure. A 2 μg dose of estradiol benzoate (EB) primes reproductive behavior circuits without facilitating lordosis. However, 50 μg EB facilitates lordosis after 4
Autor:
Diane Bogdan, Mario J. Rebecchi, Martin Kaczocha, Martha P. Kanjiya, Dale G. Deutsch, Xiaoxue Peng, Iwao Ojima, Jennifer Luk, Matthew W. Elmes, Huilin Li, Robert C. Rizzo, Michelino Puopolo, Simon Tong, Keith M. Studholme, Yu-Han Gary Teng, Gregory Carbonetti
Publikováno v:
Molecular Pain
Background Fatty-acid-binding proteins (FABPs) are intracellular carriers for endocannabinoids, N-acylethanolamines, and related lipids. Previous work indicates that systemically administered FABP5 inhibitors produce analgesia in models of inflammato