Mosquitocidal efficacy and pharmacokinetics of single-dose ivermectin versus three-day dose regimen for malaria vector control compared with albendazole and no treatment: An open-label randomized controlled trial

Autor: Yvonne Kamau, Mercy Tuwei, Caroline Wanjiku, Kelly Ominde, Mwanajuma Ngama, Jonathan Karisa, Lawrence Babu, Martha Muturi, Mwaganyuma Mwatasa, Jane Adetifa, Charlotte Kern, Urs Duthaler, Felix Hammann, Regina Rabinovich, Carlos Chaccour, Marta Ferreira Maia

Publikováno v: International Journal of Infectious Diseases, Vol 148, Iss , Pp 107236- (2024)

Objectives: When malaria vectors consume ivermectin in a blood meal, their survival probability decreases, potentially reducing malaria transmission during mass drug administrations. However, questions remain regarding the optimal dosing. This study

Externí odkaz: https://doaj.org/article/2b33b23b18584e9c934a8b13e240d80e

Characterization of Anopheles gambiae D7 salivary proteins as markers of human–mosquito bite contact

Autor: Brenda Oseno, Faith Marura, Rodney Ogwang, Martha Muturi, James Njunge, Irene Nkumama, Robert Mwakesi, Kennedy Mwai, Martin K. Rono, Ramadhan Mwakubambanya, Faith Osier, James Tuju

Publikováno v: Parasites & Vectors, Vol 15, Iss 1, Pp 1-8 (2022)

Abstract Background Malaria is transmitted when infected Anopheles mosquitoes take a blood meal. During this process, the mosquitoes inject a cocktail of bioactive proteins that elicit antibody responses in humans and could be used as biomarkers of e

Externí odkaz: https://doaj.org/article/edb10805f077485db2e55662e0077987

Potential metabolic resistance mechanisms to ivermectin in Anopheles gambiae: a synergist bioassay study

Autor: Martin G. Wagah, Marta F. Maia, Carlos Chaccour, Felix Hammann, Patricia Nicolas, Urs Duthaler, Caroline Kiuru, Martha Muturi

Publikováno v: Nicolas, Patricia; Kiuru, Caroline; Wagah, Martin G; Muturi, Martha; Duthaler, Urs; Hammann, Felix; Maia, Marta; Chaccour, Carlos (2021). Potential metabolic resistance mechanisms to ivermectin in Anopheles gambiae: a synergist bioassay study. Parasites & Vectors, 14(1), p. 172. BioMed Central 10.1186/s13071-021-04675-9
Parasites & Vectors
Parasites & Vectors, Vol 14, Iss 1, Pp 1-12 (2021)

Background Despite remarkable success obtained with current malaria vector control strategies in the last 15 years, additional innovative measures will be needed to achieve the ambitious goals for malaria control set for 2030 by the World Health Orga

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84dcb1783c9cabd1086f8d7c1008ca08
https://doi.org/10.1186/s13071-021-04675-9