Zobrazeno 1 - 10
of 176
pro vyhledávání: '"Martha M. Eibl"'
Autor:
Christian Schoergenhofer, Georg Gelbenegger, Dzenita Hasanacevic, Léa Schöner, Margarete M. Steiner, Christa Firbas, Nina Buchtele, Ulla Derhaschnig, Andreas Tanzmann, Nina Model, Julian Larcher-Senn, Manuel Drost, Martha M. Eibl, Andreas Roetzer, Bernd Jilma
Publikováno v:
EClinicalMedicine, Vol 67, Iss , Pp 102404- (2024)
Summary: Background: Toxic shock syndrome toxin-1 (TSST-1) is a superantigen produced by Staphylococcus aureus that causes the life-threatening toxic shock syndrome. The development of a safe and immunogenic vaccine against TSST-1 remains an unmet me
Externí odkaz:
https://doaj.org/article/c5ad4265a94d4108997a1f30384cf6b2
Autor:
Kai M. T. Sauerwein, Christoph B. Geier, Roman F. Stemberger, Hüseyin Akyaman, Peter Illes, Michael B. Fischer, Martha M. Eibl, Jolan E. Walter, Hermann M. Wolf
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Previous studies on immune responses following COVID-19 vaccination in patients with common variable immunodeficiency (CVID) were inconclusive with respect to the ability of the patients to produce vaccine-specific IgG antibodies, while patients with
Externí odkaz:
https://doaj.org/article/3308e5a39f834013a21b489f74acbbd1
Autor:
Jolanda Steininger, Raphael Rossmanith, Christoph B. Geier, Alexander Leiss-Piller, Lukas Thonhauser, Simone Weiss, Johannes A. Hainfellner, Michael Freilinger, Wolfgang M. Schmidt, Martha M. Eibl, Hermann M. Wolf
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
X-linked lymphoproliferative disease (XLP1) is a combined immunodeficiency characterized by severe immune dysregulation caused by mutations in the SH2D1A/SAP gene. Loss or dysfunction of SH2D1A is associated with the inability in clearing Epstein-Bar
Externí odkaz:
https://doaj.org/article/2eebc92408de435f91bba4bf07cc47a5
Publikováno v:
Toxins, Vol 14, Iss 9, p 595 (2022)
Staphylococcus aureus is a human and animal pathogen as well as a commensal bacterium. It can be a causative agent of severe, life-threatening infections with high mortality, e.g., toxic shock syndrome, septic shock, and multi-organ failure. S. aureu
Externí odkaz:
https://doaj.org/article/5a3d3f14e1ce4c4ab4959d787f46e539
Autor:
Jolanda Steininger, Alexander Leiss-Piller, Christoph B. Geier, Raphael Rossmanith, Reem Elfeky, David Bra, Herbert Pichler, Anita Lawitschka, Natascha Zubarovskaya, Gottfried Artacker, Susanne Matthes-Leodolter, Martha M. Eibl, Hermann M. Wolf
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Mutations of the interleukin 2 receptor γ chain (IL2RG) result in the most common form of severe combined immunodeficiency (SCID), which is characterized by severe and persistent infections starting in early life with an absence of T cells and natur
Externí odkaz:
https://doaj.org/article/2b77362089564493a8a81cc8686be4d6
Autor:
Christoph B. Geier, Jocelyn R. Farmer, Zsofia Foldvari, Boglarka Ujhazi, Jolanda Steininger, John W. Sleasman, Suhag Parikh, Meredith A. Dilley, Sung-Yun Pai, Lauren Henderson, Melissa Hazen, Benedicte Neven, Despina Moshous, Svetlana O. Sharapova, Snezhina Mihailova, Petya Yankova, Elisaveta Naumova, Seza Özen, Kevin Byram, James Fernandez, Hermann M. Wolf, Martha M. Eibl, Luigi D. Notarangelo, Leonard H. Calabrese, Jolan E. Walter
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Vasculitis can be a life-threatening complication associated with high mortality and morbidity among patients with primary immunodeficiencies (PIDs), including variants of severe and combined immunodeficiencies ((S)CID). Our understanding of vasculit
Externí odkaz:
https://doaj.org/article/aaa9d21e5e644f5eb95e19b5062e8648
Autor:
Christoph B. Geier, Kai M. T. Sauerwein, Alexander Leiss-Piller, Isabella Zmek, Michael B. Fischer, Martha M. Eibl, Hermann M. Wolf
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
B cell activation via the B cell receptor (BCR) signalosome involves participation of signaling molecules such as BTK and BLNK. Genetic defects in these molecules are known to impair B cell differentiation and subsequently lead to agammaglobulinemia.
Externí odkaz:
https://doaj.org/article/f8f0c62524f34c26822bffbdec8a3f16
Publikováno v:
Expert Review of Vaccines, Vol 16, Iss 2, Pp 81-83 (2017)
Externí odkaz:
https://doaj.org/article/6cb790955b644303856fa081803cba1e
Autor:
Andreas Roetzer, Norbert Stich, Nina Model, Michael Schwameis, Christa Firbas, Bernd Jilma, Martha M. Eibl
Publikováno v:
Toxins, Vol 12, Iss 10, p 640 (2020)
Staphylococcal superantigen toxins lead to a devastating cytokine storm resulting in shock and multi-organ failure. We have previously assessed the safety and immunogenicity of a recombinant toxic shock syndrome toxin 1 variant vaccine (rTSST-1v) in
Externí odkaz:
https://doaj.org/article/bb448897e7ae4b12a99d91c5806d4944
Publikováno v:
Toxins, Vol 6, Iss 6, Pp 1724-1741 (2014)
Toxic shock syndrome (TSS) results from the host’s overwhelming inflammatory response and cytokine storm mainly due to superantigens (SAgs). There is no effective specific therapy. Application of immunoglobulins has been shown to improve the outcom
Externí odkaz:
https://doaj.org/article/7d3c42f74cdb4e78b4fe4df251cf958b