Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Martha L. Dorris"'
Autor:
Mylinh T. Nguyen, Robert E. Hammer, Eilon Barnea, Martha L. Dorris, Nimman Satumtira, Joel D. Taurog, Tri M. Tran, Dganit Melamed Kadosh, Robert A. Colbert, Arie Admon, Yael Haimovich
Publikováno v:
Molecular & Cellular Proteomics. 16:642-662
HLA-B27 is a class I major histocompatibility (MHC-I) allele that confers susceptibility to the rheumatic disease ankylosing spondylitis (AS) by an unknown mechanism. ERAP1 is an aminopeptidase that trims peptides in the endoplasmic reticulum for bin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2867d905a5425853edc37c3f597d684f
https://doi.org/10.1074/mcp.m116.066241
https://doi.org/10.1074/mcp.m116.066241
Autor:
Joel D. Taurog, Leonie M. van Duivenvoorde, James A. Richardson, Kenneth S. K. Tung, F. Kent Hamra, Nimman Satumtira, Claudia Rival, John M. Shelton, Margaret Sun, Robert E. Hammer, Martha L. Dorris
Publikováno v:
Arthritis and rheumatism, 64(8), 2518-2528. John Wiley and Sons Inc.
Objective Male rats transgenic for HLA–B27 and human β2-microglobulin (hβ2m) spontaneously develop epididymoorchitis (EO) preceding the development of spondylarthritis (SpA). In the specific B27/hβ2m-transgenic rat cross-strain (21-3 × 382-2)F1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3aba974e12665d526876d054e4588afb
https://doi.org/10.1002/art.34480
https://doi.org/10.1002/art.34480
Autor:
James A. Richardson, Jie Shang, Joel D. Taurog, Robert E. Hammer, Nimman Satumtira, Martha L. Dorris, Tri M. Tran
Publikováno v:
Arthritis & Rheumatism. 54:1317-1327
Objective Ankylosing spondylitis and related spondylarthritides are associated with HLA–B27, and also with intestinal inflammation, by unknown mechanisms. The folded HLA–B27 molecule is a trimer of heavy chain, β2-microglobulin (β2m), and short
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b07a2ab0f59e3198c4d4e55ac5a9472d
https://doi.org/10.1002/art.21740
https://doi.org/10.1002/art.21740
Autor:
Tri M. Tran, Martha L. Dorris, Ekkehard May, Eiichi Furuta, Nimman Satumtira, Andrew Z. Wang, Joel D. Taurog
Publikováno v:
The Journal of Immunology. 172:5110-5119
To test the hypothesis that HLA-B27 predisposes to disease by forming disulfide-linked homodimers, we examined rats transgenic for HLA-B27, mutant Cys67Ser HLA-B27, or HLA-B7. In splenic Con A blasts from high transgene copy B27 lines that develop in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb943692c8b42ff1d4d21eea601c0842
https://doi.org/10.4049/jimmunol.172.8.5110
https://doi.org/10.4049/jimmunol.172.8.5110
Autor:
Clive A. Slaughter, James A. Richardson, Martha L. Dorris, Richard C. Jones, Nimman Satumtira, Simon J. Gaskell, Shanna D. Maika, Ming Zhou, William A. Simmons, R. Balfour Sartor, Robert E. Hammer, Alain Sayad, Joel D. Taurog, Robert S. Bordoli
Publikováno v:
Journal of Experimental Medicine. 188:877-886
Human histocompatibility leukocyte antigen B27 is highly associated with the rheumatic diseases termed spondyloarthropathies, but the mechanism is not known. B27 transgenic rats develop a spontaneous disease resembling the human spondyloarthropathies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ce93b393f55894edcfbedf719ee570b7
https://doi.org/10.1084/jem.188.5.877
https://doi.org/10.1084/jem.188.5.877
Publikováno v:
Biochemical Pharmacology. 49:701-709
6-Propylthiouracil (PTU), a widely used antithyroid drug for the treatment of Graves' disease, is also a potent inhibitor of Type I iodothyronine deiodinase (ID-1). Inhibition of ID-1 was attributed initially to the formation of a mixed disulfide bet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c66c3b00d3c40a5b04523a588dc50c63
https://doi.org/10.1016/0006-2952(94)00505-g
https://doi.org/10.1016/0006-2952(94)00505-g
Autor:
Nimman Satumtira, Paul P. Tak, Leonie M. van Duivenvoorde, Melissa N van Tok, Dominique Baeten, Joel D. Taurog, Kurt Redlich, Martha L. Dorris
Publikováno v:
Arthritis and rheumatism, 64(10), 3210-3219. John Wiley and Sons Inc.
Objective Inhibition of inflammation and destruction, but not of osteoproliferation, in patients with spondylarthritis (SpA) treated with anti–tumor necrosis factor raises the question of how these three processes are interrelated. This study was u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6551b4b0f0773382c7052a5115f52e8
https://pubmed.ncbi.nlm.nih.gov/22736144
https://pubmed.ncbi.nlm.nih.gov/22736144
Publikováno v:
Archives of Biochemistry and Biophysics. 315:90-99
Single turnover experiments were performed with horseradish peroxidase (HRP) to study the mechanism of peroxidase-catalyzed coupling and its stimulation by low concentrations of free diiodotyrosine (DIT). HRP was used because, unlike thyroid peroxida
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cbae1bc8ec2a2518f36b72e75ac42595
https://doi.org/10.1006/abbi.1994.1475
https://doi.org/10.1006/abbi.1994.1475
Publikováno v:
Archives of Biochemistry and Biophysics. 315:82-89
Biosynthesis of thyroxine in the thyroid gland involves a reaction between two diiodotyrosyl residues within the same molecule of thyroglobulin, a large, thyroid-specific glycoprotein. This reaction, generally referred to as the coupling reaction, is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c85f8633f4b2b0a3cef39f6721579e29
https://doi.org/10.1006/abbi.1994.1474
https://doi.org/10.1006/abbi.1994.1474
Publikováno v:
Biochemical Pharmacology. 48:1447-1453
Methimazole (MMI), unlike propylthiouracil (PTU) is a poor inhibitor of type I iodothyronine deiodinase (ID-1). Inhibition of the enzyme by PTU was attributed initially to formation of a mixed disulfide between PTU and a cysteine residue at the activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5d5bc9dcf2900c423d9c04e9061491a
https://doi.org/10.1016/0006-2952(94)90569-x
https://doi.org/10.1016/0006-2952(94)90569-x