Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Martha L Healy-Fried"'
Autor:
Bo Qi, Stanley Ng, Richard Chen, Martha L Healy-Fried, Josaih C Adaelu, Rajesh Ambat, Paul Balderes, Julia Lee, Troii Hall, Yun (Kenneth) Kang, Behnam Shanehsaz, William D Holmes, Dale L. Ludwig, Michael Barry, Matthew D Sauffer, Warren R. Emery, Amy Huebner
Publikováno v:
Pharmaceutical Bioprocessing. 3:477-487
6-Chloro- and 6-bromopurines can cross the blood-brain barrier and in situ give rise to substrates of multidrug resistance-associated proteins (MRPs). The electrophilic purines form glutathione conjugates in reactions catalyzed by intracellular gluta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5bf6e25f7cec067196cbc97bda8b19af
https://doi.org/10.4155/pbp.15.28
https://doi.org/10.4155/pbp.15.28
Autor:
Martha L. Healy-Fried, Huijong Han, Ernst Schönbrunn, T. Funke, Paul A. Bartlett, David G. Alberg
Publikováno v:
Biochemistry. 46:13344-13351
The shikimate pathway enzyme 5-enolpyruvylshikimate-3-phosphate synthase (EPSP synthase or EPSPS) is best known as the target of the herbicide glyphosate. EPSPS is also considered an attractive target for the development of novel antibiotics since th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b7fb4aef67481311b5e8039d5983eb8
https://doi.org/10.1021/bi701095u
https://doi.org/10.1021/bi701095u
Autor:
Huijong Han, Yan Yang, S.H. Olesen, Ernst Schönbrunn, T. Funke, Andreas Becker, Martha L. Healy-Fried
The shikimate pathway enzyme 5-enolpyruvylshikimate-3-phosphate synthase (EPSPS) is the target of the broad spectrum herbicide glyphosate. The genetic engineering of EPSPS led to the introduction of glyphosate-resistant crops worldwide. The genetical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70695e2af7c4521b5abdcc924d75b4df
https://europepmc.org/articles/PMC2665107/
https://europepmc.org/articles/PMC2665107/
Publikováno v:
The Journal of biological chemistry. 282(45)
Glyphosate, the world's most used herbicide, is a massive success because it enables efficient weed control with minimal animal and environmental toxicity. The molecular target of glyphosate is 5-enolpyruvylshikimate-3-phosphate synthase (EPSPS), whi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b5eee76163357a6074107fd430952d9
https://pubmed.ncbi.nlm.nih.gov/17855366
https://pubmed.ncbi.nlm.nih.gov/17855366
The engineering of transgenic crops resistant to the broad-spectrum herbicide glyphosate has greatly improved agricultural efficiency worldwide. Glyphosate-based herbicides, such as Roundup, target the shikimate pathway enzyme 5-enolpyruvylshikimate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f93a2e27352ffe9c0fc8cf88f17e2a59
https://europepmc.org/articles/PMC1559744/
https://europepmc.org/articles/PMC1559744/