Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Martha H. Marshall"'
Publikováno v:
Investigational New Drugs. 10:269-273
Interleukin-4 is a highly pleiotropic T-cell derived lymphokine that has been reported to stimulate a host cell-mediated antitumor response. Recombinant human interleukin-4 (rhuIL-4) is currently undergoing clinical phase I trials. We have studied th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d34cffbddded86f9b327a0420416459c
https://doi.org/10.1007/bf00944180
https://doi.org/10.1007/bf00944180
Publikováno v:
Anti-Cancer Drugs. 3:143-146
2',2'-Difluorodeoxycytidine (LY 188011, Gemcitabine) is a novel pyrimidine antimetabolite with promising activity in preclinical models for leukemia and solid tumors. Phase I clinical trials with the agent are ongoing. In order to better define types
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ca9536c9586eb55b8b844b9e427e8ee
https://doi.org/10.1097/00001813-199204000-00012
https://doi.org/10.1097/00001813-199204000-00012
Autor:
David C. Heimbrook, Robert Z. Maigetter, Martha H. Marshall, Wayne K. Herbert, Steven M. Stirdivant, Daniel D. Von Hoff, Oliff Allen I, Janet D. Ahern
Publikováno v:
Investigational New Drugs. 10:17-22
Transforming growth factor-alpha-Pseudomonas exotoxin-40 (TP40) is a recombinant fusion protein. TP40 consists of the entire human transforming growth factor-alpha (TGF alpha) protein fused to a 40,000 Da. segment of the Pseudomonas exotoxin A protei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e726e5908e001707186de2965273e428
https://doi.org/10.1007/bf01275472
https://doi.org/10.1007/bf01275472
Autor:
Michael E. Ross, John G. Kuhn, Milton V. Marshall, G. David Roodman, Donna R. Degen, Martha H. Marshall, Daniel D. Von Hoff
Publikováno v:
Stem cells (Dayton, Ohio). 11(1)
Hepsulfam (sulfamic acid 1,7-heptanediyl ester, NSC 329680) is an alkylating agent currently in Phase I clinical trials. Hepsulfam was developed as an analog of busulfan, an alkylating agent that is used to treat patients with chronic myelogenous leu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e723b74ca77a4462d5f0dae9b48393e
https://pubmed.ncbi.nlm.nih.gov/8457783
https://pubmed.ncbi.nlm.nih.gov/8457783
Autor:
Howard A. Burris, Axel R. Hanauske, Martha H. Marshall, John G. Kuhn, Daniel D. Von Hoff, Randall K. Johnson, Susan G. Hilsenbeck
Publikováno v:
Journal of the National Cancer Institute. 84(23)
BACKGROUND Topotecan [(S)-9-dimethylaminomethyl(10-hydroxy-camptothecin), NSC 609699, SK&F 104864A], a semisynthetic analogue of the natural product camptothecin, is a cell cycle-specific drug that exerts antineoplastic activity through inhibition of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b56f1f84bf4aecd55005ffae5c17f21
https://pubmed.ncbi.nlm.nih.gov/1331485
https://pubmed.ncbi.nlm.nih.gov/1331485
Autor:
Stuckey J, Von Hoff Dd, Martha H. Marshall, Banks P, A.-R. Hanauske, S. G. Hilsenbeck, Leahy M, Degen D
Publikováno v:
Journal of immunotherapy : official journal of the Society for Biological Therapy. 11(3)
Interleukin-1 alpha (IL-1 alpha) is a low-molecular-weight cytokine that regulates proliferation and differentiation of lymphatic and myeloid cells. It also has pleiotropic activity on a variety of other target cells and acts as an important mediator
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21b17c0d3f7683bb6999523ef3f31c30
https://pubmed.ncbi.nlm.nih.gov/1515420
https://pubmed.ncbi.nlm.nih.gov/1515420
Autor:
A.-R. Hanauske, Joseph J. McPhillips, Martha H. Marshall, S. G. Hilsenbeck, Degen D, D. D. Von Hoff
Publikováno v:
Anti-cancer drugs. 3(1)
Ilmofosine (BM 41.440, 1-hexadecylthio-2-methoxymethyl-rac-glycero-3-phosphocholine) is a synthetic alkyl lysophospholipid analog with activity against a variety of tumor models in vitro and in vivo. The i.v. form is presently undergoing early clinic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32e4944e60a38a782bbfb76f7e0544b7
https://pubmed.ncbi.nlm.nih.gov/1623215
https://pubmed.ncbi.nlm.nih.gov/1623215
Autor:
Martha H. Marshall, Geoffrey R. Weiss, W. A. Knight, Gary M. Clark, Charles F. LeMaistre, D. D. Von Hoff, J. B. Buchok
Publikováno v:
Journal of Clinical Oncology. 4:1827-1834
Several preclinical and clinical studies have documented that dose or dose intensity of chemotherapeutic agents are important factors for response of patients' tumors. This finding has prompted empiric trials of certain chemotherapeutic agents in hig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cad3c61cad6b9e8241047940beb57c0
https://doi.org/10.1200/jco.1986.4.12.1827
https://doi.org/10.1200/jco.1986.4.12.1827
Autor:
Robert L. Pardue, J. B. Buchok, Axel-R. Hanauske, Parul Hazarika, Martha H. Marshall, Carlos L. Arteaga, Gary M. Clark, Daniel D. Von Hoff
Publikováno v:
Cancer. 61:1832-1837
Transforming growth factors (TGF) are polypeptides that stimulate anchorage-independent growth of various nontransformed cells in vitro. Transforming growth factors have been found in tumor extracts and in the urine of cancer patients. The specific q
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::612ab88f9a99a588be10c9101fa0318a
https://doi.org/10.1002/1097-0142(19880501)61:9<1832::aid-cncr2820610919>3.0.co
https://doi.org/10.1002/1097-0142(19880501)61:9<1832::aid-cncr2820610919>3.0.co
Autor:
Martha H. Marshall, Axel-R. Hanauske, Daniel D. Von Hoff, Victoria A. Muggia, Ulrike Hanauske
Publikováno v:
International journal of cell cloning. 5(2)
Vanadium is a trace element widely distributed in nature. It interferes with a variety of enzyme systems and is also reported to increase DNA-synthesis and in vitro clonal growth of human and mouse fibroblasts. The purpose of the present study was to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f681be398c1eca77747c23d8c6dd381
https://pubmed.ncbi.nlm.nih.gov/3106514
https://pubmed.ncbi.nlm.nih.gov/3106514