Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Martha G. Sensel"'
Autor:
Laura C. Bowman, Milton J. Finegold, John J. Quinn, Marleta Reynolds, Jorge A. Ortega, Joel E. Haas, Martha G. Sensel, Mark Krailo, James H. Feusner, Kurt D. Newman, Robert P. Castleberry, Edwin C. Douglass, Howard M. Katzenstein, Marcio H. Malogolowkin, Wen Liu-Mares
Publikováno v:
Journal of Clinical Oncology. 20:2789-2797
PURPOSE: To determine surgical resectability, event-free survival (EFS), and toxicity in children with hepatocellular carcinoma (HCC) randomized to treatment with either cisplatin (CDDP), vincristine, and fluorouracil (regimen A) or CDDP and continuo
Autor:
Gregory H. Reaman, Peter G. Steinherz, Bruce C. Bostrom, Paul S. Gaynon, Harland N. Sather, Fatih M. Uckun, Raymond J. Hutchinson, Beverly J. Lange, Martha G. Sensel, Mei K. L. La, Nyla A. Heerema, James B. Nachman
Publikováno v:
Cancer. 94:1102-1110
BACKGROUND Recurring breakpoints in chromosome bands 15q13-15 occur infrequently in leukemia. To the authors' knowledge, the clinical significance of these breakpoints in childhood acute lymphoblastic leukemia (ALL) has not been previously investigat
Autor:
Paul S. Gaynon, Peter G. Steinherz, Beverly J. Lange, Bruce Bostrom, Martha G. Sensel, Mei K. Lee, James B. Nachman, Daniel O. Stram, Raymond J. Hutchinson, Harland Sather
Publikováno v:
Journal of Clinical Oncology. 19:1916-1925
PURPOSE: We used duration of hospitalization as a surrogate for cost and event-free survival as a measure of effectiveness to estimate the cost-effectiveness ratios of various treatment regimens on Children’s Cancer Group trials for acute lymphobla
Autor:
Mireille Sarquis, Fatih M. Uckun, Michael Willoughby, Daniel O. Stram, Paul S. Gaynon, Martha G. Sensel
Publikováno v:
Leukemia & Lymphoma. 40:279-285
Isolated extramedullary relapse in childhood acute lymphoblastic leukemia (ALL) is associated frequently with the T-lineage immunophenotype and may be accompanied by occult bone marrow disease. We employed highly sensitive multiparameter flow cytomet
Autor:
Harland N. Sather, Nyla A. Heerema, Raymond J. Hutchinson, Paul S. Gaynon, James B. Nachman, Beverly J. Lange, Bruce Bostrom, Mei K. Lee, Peter G. Steinherz, Martha G. Sensel, Fatih M. Uckun, Gregory H. Reaman
Publikováno v:
Journal of Clinical Oncology. 18:3837-3844
PURPOSE: Little is known about nonrandom deletions of chromosome bands 13q12 to 13q14 (13q12–14) in acute lymphoblastic leukemia (ALL). We determined the prognostic significance of cytogenetically identified breakpoints in 13q12–14 in children wi
Autor:
Mark Krailo, Marleta Reynolds, Martha G. Sensel, Denis R. King, Wen Liu-Mares, Joel E. Haas, John J. Quinn, Jorge A. Ortega, Edwin C. Douglass, Milton J. Finegold, James H. Feusner
Publikováno v:
Journal of Clinical Oncology. 18:2665-2675
PURPOSE: Previous studies demonstrated that chemotherapy with either cisplatin, vincristine, and fluorouracil (regimen A) or cisplatin and continuous infusion doxorubicin (regimen B) improved survival in children with hepatoblastoma. The current tria
Autor:
Peter G. Steinherz, James B. Nachman, Fatih M. Uckun, Raymond Hutchinson, Nyla A. Heerema, Paul S. Gaynon, Beverly J. Lange, Harland N. Sather, Martha G. Sensel, Mei K. Lee, Bruce Bostrom
Publikováno v:
Cancer. 88:1945-1954
BACKGROUND The authors have determined the prognostic significance of cytogenetically detectable 12p abnormalities, which are frequent in children with acute lymphoblastic leukemia (ALL), in a large cohort of patients treated on risk-adjusted protoco
Autor:
Fatih M. Uckun, Paul S. Gaynon, Mei K. Lee, Nyla A. Heerema, Peter G. Steinherz, Martha G. Sensel, Beverly J. Lange, Harland N. Sather, Raymond J. Hutchinson, James B. Nachman, Bruce Bostrom
Publikováno v:
Leukemia & Lymphoma. 36:467-478
We have compared outcome for 167 (9.0%) children with a del(6q) and 1713 (91%) children without a del(6q) treated on Children's Cancer Group (CCG) risk-adjusted treatment protocols for acute lymphoblastic leukemia (ALL). Thirty-three patients had a d
Autor:
James B. Nachman, Gregory H. Reaman, Lisa M. Chelstrom, Paul S. Gaynon, Fatih M. Uckun, Bruce Bostrom, Martha G. Sensel, Harland N. Sather, Onur Ek, Peter G. Steinherz, Barbara Waurzyniak, Mireille Sarquis
Publikováno v:
Leukemia & Lymphoma. 32:475-487
Contemporary intensive therapies are effective for the majority of pediatric T-lineage acute lymphoblastic leukemia (ALL) patients, thus current challenge is to identify patients who may benefit from alternative treatment modalities. Previously, we d