Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Martha F. Kramer"'
Autor:
Joseph C. Mellor, David M. Knipe, Donald M. Coen, Igor Jurak, Frederick P. Roth, Alison L. van Lint, Martha F. Kramer
Publikováno v:
Journal of Virology. 84:4659-4672
Certain viruses use microRNAs (miRNAs) to regulate the expression of their own genes, host genes, or both. Previous studies have identified a limited number of miRNAs expressed by herpes simplex viruses 1 and 2 (HSV-1 and -2), some of which are conse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::301ffb27fa7e4aff53ea9a8226179e65
https://doi.org/10.1128/jvi.02725-09
https://doi.org/10.1128/jvi.02725-09
Autor:
Jennifer L. Umbach, Donald M. Coen, Bryan R. Cullen, Igor Jurak, Martha F. Kramer, Heather W. Karnowski
Publikováno v:
Nature. 454:780-783
Herpesviruses are characterized by their ability to maintain life-long latent infections in their animal hosts. However, the mechanisms that allow establishment and maintenance of the latent state remain poorly understood. Herpes simplex virus 1 (HSV
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ac59d395231e2e3438369b79f7fd2f2
https://doi.org/10.1038/nature07103
https://doi.org/10.1038/nature07103
Autor:
Holly A. Holman, Frederick P. Roth, Donald M. Coen, Martha F. Kramer, Jia Zhu, David M. Knipe, W. James Cook
Publikováno v:
Journal of Virology. 77:9533-9541
The persistence of herpes simplex virus (HSV) and the diseases that it causes in the human population can be attributed to the maintenance of a latent infection within neurons in sensory ganglia. Little is known about the effects of latent infection
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::454edebc71a3cb36e4c6c3a1bec9e404
https://doi.org/10.1128/jvi.77.17.9533-9541.2003
https://doi.org/10.1128/jvi.77.17.9533-9541.2003
Publikováno v:
Current Eye Research. 26:185-194
To quantify and characterize immune protection from herpes simplex virus (HSV) latent infection in mice following corneal challenge.Mice immunized or mock-immunized and boosted in the flank with an HSV replication-deficient mutant were challenged by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba7017fdcd424d75e17a2969855c9cbc
https://doi.org/10.1076/ceyr.26.3.185.14891
https://doi.org/10.1076/ceyr.26.3.185.14891
Publikováno v:
Journal of Virology. 74:7963-7971
A number of studies have shown that replication-defective mutant strains of herpes simplex virus (HSV) can induce protective immunity in animal systems against wild-type HSV challenge. However, all of those studies used viruses with single mutations.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c8bc5883f2b8f286609ae518e6fe5a3
https://doi.org/10.1128/jvi.74.17.7963-7971.2000
https://doi.org/10.1128/jvi.74.17.7963-7971.2000
Autor:
Martha F. Kramer, Donald M. Coen
Publikováno v:
Journal of Virology. 69:1389-1399
Herpes simplex virus establishes latency in nervous tissue in which it is maintained for the life of the mammalian host, with occasional reactivation leading to subsequent spread. Latency-associated transcripts are abundant during latency, but viral
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54ae06348f12a66ed852699007d3fdd2
https://doi.org/10.1128/jvi.69.3.1389-1399.1995
https://doi.org/10.1128/jvi.69.3.1389-1399.1995
Autor:
Alfred L. Roca, Xandra O. Breakefield, David W. Garber, Julie K. Andersen, Ole Isacson, Martha F. Kramer, David M. Knipe, Donald M. Coen, Gudarz Davar, William R. Bebrin, M Kosz-Vnenchak
Publikováno v:
The Journal of Comparative Neurology. 339:3-11
To achieve gene delivery to sensory neurons of the trigeminal ganglion, thymidine kinase-negative (TK−) herpes simplex viruses (HSV) containing the reporter gene lacZ (the gene for E. coli β-galactosidase) downstream of viral (in vectors RH116 and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5b5fea9c520b7f822cbcfdb70bb4fc1
https://doi.org/10.1002/cne.903390103
https://doi.org/10.1002/cne.903390103
Autor:
Donald M. Coen, Martha F. Kramer
Publikováno v:
Current Protocols in Molecular Biology
This unit describes a method for amplifying DNA enzymatically by the polymerase chain reaction (PCR) and for optimizing this reaction for the sequence and primer set of interest. Important variables that can influence the outcome of PCR include the M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c701fa77703ee5aeb22000de576411c
https://pubmed.ncbi.nlm.nih.gov/21959762
https://pubmed.ncbi.nlm.nih.gov/21959762
Autor:
Martha F. Kramer
Publikováno v:
Current Protocols in Molecular Biology
This unit presents a specific and sensitive quantitative reverse-transcription PCR (RT-qPCR) method for measuring individual microRNAs (miRNAs) in tissue or cultured cells. miRNAs are 17 to 24 nucleotides (nt) in length. Standard and quantitative PCR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab62210fdd4ea162683932acb33fd9ff
https://pubmed.ncbi.nlm.nih.gov/21732315
https://pubmed.ncbi.nlm.nih.gov/21732315
Autor:
Sandrine Boissel, Igor Jurak, Donald M. Coen, David M. Knipe, Jean M. Pesola, Martha F. Kramer
Publikováno v:
Virology. 417(2)
Several herpes simplex virus 1 microRNAs are encoded within or near the latency associated transcript (LAT) locus, and are expressed abundantly during latency. Some of these microRNAs can repress the expression of important viral proteins and are hyp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db1c7371ea4efc79106f4cb597b85162
https://pubmed.ncbi.nlm.nih.gov/21782205
https://pubmed.ncbi.nlm.nih.gov/21782205