Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Martha Elizabeth Blaney"'
Autor:
Susan E. Morgan-Lappe, Zev A. Wainberg, Ramesh K. Ramanathan, Huibin Yue, Martha Elizabeth Blaney, Louie Naumovski, John H. Strickler, Lan Wang, John Nemunaitis, George W. Sledge, Erika Hamilton, Sreeneeranj Kasichayanula, Minal A. Barve, Michael S. Gordon, Monica Motwani
Publikováno v:
Molecular cancer therapeutics, vol 20, iss 10
Dilpacimab (formerly ABT-165), a novel dual-variable domain immunoglobulin, targets both delta-like ligand 4 (DLL4) and VEGF pathways. Here, we present safety, pharmacokinetic (PK), pharmacodynamic (PD), and preliminary efficacy data from a phase I s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53aadea40691048a1e4ced92e1801356
https://doi.org/10.1158/1535-7163.mct-20-0985
https://doi.org/10.1158/1535-7163.mct-20-0985
Autor:
Jordi Bruix, Talia Golan, Gregory Vosganian, Kathy D. Miller, Anthony W. Tolcher, Susan Lacy, Satwant Lally, Toshio Shimizu, Arjun Vasant Balar, Stacie Lambert, John D. Powderly, Martha Elizabeth Blaney, Xiaowen Guan, Rachel S Leibman, Patricia LoRusso, Albiruni Ryan Abdul Razak, Loren S. Michel
Publikováno v:
Cancer Research. 81:CT207-CT207
Background Glycoprotein-A repetitions predominant (GARP) regulates membrane-bound transforming growth factor β1 (TGFβ1), an immunosuppressive cytokine. ABBV-151 is a first-in-class monoclonal antibody (mAb) that binds to the GARP-TGFβ1 complex and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::364f5a4c8f04997c92b89ba73dc652f9
https://doi.org/10.1158/1538-7445.am2021-ct207
https://doi.org/10.1158/1538-7445.am2021-ct207
Autor:
M. Nagasaka, Martha Elizabeth Blaney, T. Dai, J. Grewal, Stacie Lambert, Y. Li, Missak Haigentz, Aru Panwar, C. Maurice-Dror, Daniel Da Costa, I. Moreno, Maulik Patel, Ari Rosenberg, Jordan Berlin, C. Le Tourneau, I. Gluck, Michael A. McDevitt, Xiuning Le, Kathryn A. Gold, Maura L. Gillison
Publikováno v:
Annals of Oncology. 31:S685
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cab1a987d6fc2b2ea1723583aee482a2
https://doi.org/10.1016/j.annonc.2020.08.1090
https://doi.org/10.1016/j.annonc.2020.08.1090
Autor:
Kathy D. Miller, Stacie Lambert, Albiruni Ryan Abdul Razak, Satwant Lally, Talia Golan, Toshio Shimizu, Arjun Vasant Balar, Jordi Bruix, Anthony W. Tolcher, Patricia LoRusso, Rachel S Leibman, Susan Lacy, John D. Powderly, Martha Elizabeth Blaney, Loren S. Michel, Gregory Vosganian, X. Guan
Publikováno v:
Annals of Oncology. 31:S499
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f2723b40ae7fe5202ceb946dcbe5bc16
https://doi.org/10.1016/j.annonc.2020.08.710
https://doi.org/10.1016/j.annonc.2020.08.710
Autor:
Talia Golan, Kathy D. Miller, Michael A. McDevitt, Anthony W. Tolcher, John D. Powderly, Daniel Dacosta, Patricia LoRusso, Martha Elizabeth Blaney, William R Henner
Publikováno v:
Journal of Clinical Oncology. 38:TPS3147-TPS3147
TPS3147 Background: CD40 is a key costimulatory molecule for both the innate and adaptive immune systems that is essential for T-cell activation and proliferation. OX40 is a costimulatory molecule that is involved in enhancing nascent immune response
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::339df974a1db83cceabfa5618dd779f8
https://doi.org/10.1200/jco.2020.38.15_suppl.tps3147
https://doi.org/10.1200/jco.2020.38.15_suppl.tps3147
Autor:
Eric P. Winer, Amy C. Peterson, Javier Cortes, Vandana G. Abramson, Tiffany A. Traina, Maureen E. Trudeau, Joyce O'Shaughnessy, Denise A. Yardley, Peter Schmid, Martha Elizabeth Blaney, Lee S. Schwartzberg, Joyce Steinberg, Catherine M. Kelly, Rita Nanda, Iulia Cristina Tudor, Ahmad Awada, Clifford A. Hudis
Publikováno v:
Cancer Research. 75:P5-19
Background AR expression has been observed in 10-30% of patients with TNBC. AR+ TNBC cell lines demonstrated enhanced growth in response to androgen stimulation that is inhibited by enzalutamide (ENZA), a potent oral inhibitor of AR signaling. AR+ TN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e29b451a93f001e34fff456baca5c4d
https://doi.org/10.1158/1538-7445.sabcs14-p5-19-09
https://doi.org/10.1158/1538-7445.sabcs14-p5-19-09
Autor:
Martha Elizabeth Blaney, Huibin Yue, Louie Naumovski, Sreeneeranj Kasichayanula, John H. Strickler, Lan Wang, Monica Motwani, Zev A. Wainberg
Publikováno v:
Annals of Oncology. 29:v83-v84
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cca5b6e2b25c8765bf930a6a6ae4f0c6
https://doi.org/10.1093/annonc/mdy151.295
https://doi.org/10.1093/annonc/mdy151.295
Autor:
John H. Strickler, Huibin Yue, Louie Naumovski, Lan Wang, Martha Elizabeth Blaney, Monica Motwani, Zev A. Wainberg, Sreeneeranj Kasichayanula
Publikováno v:
Journal of Clinical Oncology. 37:TPS720-TPS720
TPS720 Background: Dual variable domain immunoglobulin ABT-165 targets human vascular endothelial growth factor (VEGF) and delta-like ligand 4 (DLL4). Combined VEGF and DLL4 blockade increased inhibition of subcutaneous xenograft growth of human colo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::689a8aafb6e809ff1e326d5c3b68abb8
https://doi.org/10.1200/jco.2019.37.4_suppl.tps720
https://doi.org/10.1200/jco.2019.37.4_suppl.tps720
Autor:
Joyce Steinberg, Ayca Gucalp, Tiffany A. Traina, Lee S. Schwartzberg, Manish R. Patel, Martha Elizabeth Blaney, Jacqueline A. Gibbons, Denise A. Yardley, Anthony D. Elias, Patricia LoRusso, Howard A. Burris, Amy C. Peterson
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 23(15)
Purpose: Several lines of evidence support targeting the androgen signaling pathway in breast cancer. Enzalutamide is a potent inhibitor of androgen receptor signaling. Preclinical data in estrogen-expressing breast cancer models demonstrated activit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33123a5490c9bcdcab8d515107569873
https://pubmed.ncbi.nlm.nih.gov/28280092
https://pubmed.ncbi.nlm.nih.gov/28280092
Autor:
Anthony W. Tolcher, Daniel E. H. Afar, K. Chung, Alexander I. Spira, Michael A. McDevitt, Anita Reddy, Martha Elizabeth Blaney, William R Henner, John D. Powderly, Apurvasena Parikh, Amita Patnaik
Publikováno v:
Annals of Oncology. 29:viii409
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e7b3b702ac638f5d81daeed148a77025
https://doi.org/10.1093/annonc/mdy288.022
https://doi.org/10.1093/annonc/mdy288.022