Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Martha E. Linsenmeyer"'
Autor:
Richard J. Simpson, Hong Ji, Leanne Bowes, David F. Frecklington, Martha E. Linsenmeyer, Yee-Foong Mok, Nelly Marmy-Conus, Donna S. Dorow, Shiva Akbarzadeh, Lisa Devereux
Publikováno v:
Journal of Biological Chemistry. 277:36280-36287
Mixed lineage kinase 2 (MLK2) is a protein kinase that signals in the stress-activated Jun N-terminal kinase signal transduction pathway. We used immunoprecipitation and mass spectrometric analysis to identify MLK2-binding proteins in cell lines with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01d00485ec3283646fe8cb2709c12b66
https://doi.org/10.1074/jbc.m204626200
https://doi.org/10.1074/jbc.m204626200
Publikováno v:
British Journal of Cancer
The p16 (CDKN2/MTS-1/INK4A) gene is one of several tumour-suppressor genes that have been shown to be inactivated by DNA methylation in various human cancers including breast tumours. We have used bisulphite genomic sequencing to examine the detailed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a9147c9de32941f665ddf70bbe6592a
https://doi.org/10.1038/sj.bjc.6690041
https://doi.org/10.1038/sj.bjc.6690041
Publikováno v:
Gene. 206:63-67
Mouse ES cells with a null mutation of the known DNA methyltransferase retain some residual DNA methylation and can methylate foreign sequences de novo. We have used bisulfite genomic sequencing to examine the sequence specificity and distributions o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c949b672b1f2a556c67576982c9640fd
https://doi.org/10.1016/s0378-1119(97)00566-0
https://doi.org/10.1016/s0378-1119(97)00566-0
Autor:
Michael Millward, Carmel G. Morton, Martha E. Linsenmeyer, Lorraine K. Webster, James F. Bishop, David M. Woodcock
Publikováno v:
JNCI: Journal of the National Cancer Institute. 85:1685-1690
Background Paclitaxel (Taxol) is the first of a new class of cytotoxic agents with activity against tumors resistant to other drugs. For clinical use, paclitaxel is currently formulated in a vehicle of 50% ethanol and 50% polyethoxylated surfactant C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bf1894ef70be83ec306aa1148e86cce
https://doi.org/10.1093/jnci/85.20.1685
https://doi.org/10.1093/jnci/85.20.1685
Autor:
J.P. Doherty, Penelope J. Crowther, Martha E. Linsenmeyer, M.W. Graham, Michael Williamson, David M. Woodcock
Publikováno v:
Gene. 98:77-82
The use of optimally methylation-tolerant mcrA − mcrB − strains has been shown to produce an over tenfold increase in the plating efficiencies of mammalian genomic libraries, compared to a superior conventional phage host strain LE392 which is mc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::497be21b326bd08f99694af20d758abd
https://doi.org/10.1016/0378-1119(91)90106-l
https://doi.org/10.1016/0378-1119(91)90106-l
Autor:
Celine B. Lawler, Martha E. Linsenmeyer, David M. Woodcock, William D. Warren, Judith P. Doherty
Publikováno v:
The Journal of biological chemistry. 272(12)
We have investigated the function and sequence specificity of DNA methylation in the hypermethylated CpG island promoter region of the endogenous human LINE-1 (L1) retrotransposon family. In nontransformed human embryonic fibroblasts, inhibition of D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f86644121beeded23746a8cea1d9db30
https://pubmed.ncbi.nlm.nih.gov/9065445
https://pubmed.ncbi.nlm.nih.gov/9065445
Autor:
Danny Rischin, Lorraine K. Webster, Michael J. Millward, Maureen E. Urch, Martha E. Linsenmeyer, David M. Woodcock
Publikováno v:
Cancer chemotherapy and pharmacology. 39(6)
Docetaxel (Taxotere, Rhone-Poulenc Rorer) and etoposide are water-insoluble drugs formulated with polysorbate 80 for intravenous administration. We have previously reported that surfactants, including polysorbate 80 and Cremophor EL, can reverse the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adb221f30cf5be7cbe97e70b0f6cc168
https://pubmed.ncbi.nlm.nih.gov/9118471
https://pubmed.ncbi.nlm.nih.gov/9118471
Autor:
David M. Woodcock, Penelope J. Crowther, Detlev H. Krüger, Martha E. Linsenmeyer, J.P. Doherty
Publikováno v:
Gene. 102(1)
The restriction endonucleases (ENases) BstNI (CC▾ATGG) and EcoRII (▾CCATGG) both cleave DNA at the same sequences, but only EcoRII produces 5-nucleotide (nt) cohesive ends and is inhibited by 5-methylation of the inner cytosine. The low-Mr fragme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c69aaf10e308a71af90a55e92ff873e
https://pubmed.ncbi.nlm.nih.gov/1650735
https://pubmed.ncbi.nlm.nih.gov/1650735
Efficient recovery of clones from the 5' end of the human L1 dispersed repetitive elements necessitates the use of deletion mcr- host strains since this region contains a CpG island which is hypermethylated in vivo. Clones recovered with conventional
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::463dfb677e00ddb208fad80873e89f9c
https://europepmc.org/articles/PMC329448/
https://europepmc.org/articles/PMC329448/
