Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Martha C. Garcia"'
Publikováno v:
Toxicology in Vitro. 25:1501-1506
The range of non-alcoholic fatty liver disease (NAFLD) includes simple hepatic steatosis, the inflammatory non-alcoholic steatohepatitis (NASH), fibrosis and cirrhosis. The accumulation of specific lipids in hepatocytes has been associated with oxida
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1c9d3950363a3a6d378a4033407b9d6
https://doi.org/10.1016/j.tiv.2011.05.011
https://doi.org/10.1016/j.tiv.2011.05.011
Autor:
Hee-Yong Kim, Martha C. Garcia
Publikováno v:
Brain Research. 768:43-48
In this study, we demonstrate that astroglial 5-HT2A receptors are linked to the mobilization of polyunsaturated fatty acids (PUFA). Stimulation of C6 glioma cells, prelabeled with [3H]arachidonate (AA, 20:4n6) and [14C]docosahexaenoate (DHA, 22:6n3)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5640388d1467216c0ed604cf7140dbd7
https://doi.org/10.1016/s0006-8993(97)00583-0
https://doi.org/10.1016/s0006-8993(97)00583-0
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism. 1083:29-36
This study has investigated the metabolic modification of [3-14C]docosatetraenoate (22:4(n−6)) and [3-14C]docosapentaenoate (22:5(n−3)) by human cells in culture. Fetal skin fibroblasts converted as much as 20% of the incoporated [ 14 C ]22:4(n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9606ccf89d24848f54eef7e9cd5da232
https://doi.org/10.1016/0005-2760(91)90121-w
https://doi.org/10.1016/0005-2760(91)90121-w
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism. 1083:37-45
This study has investigated the effect of supplementation of vascular endothelial cells with arachidonate and other polyunsaturated fatty acids on the agonist-stimulated synthesis of platelet activating factor (PAF; 1- O -alkyl-2-acetyl- sn -glycero-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36964d81b23126efa9ccbbc2076ffbfa
https://doi.org/10.1016/0005-2760(91)90122-x
https://doi.org/10.1016/0005-2760(91)90122-x
Publikováno v:
Molecular and cellular endocrinology. 220(1-2)
The masculine profile of cytochrome P450s found in male liver is determined by the episodic secretion of growth hormone characteristic of males. In turn, the female pattern of P450s observed in female rat liver is regulated by the continuous secretio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c8e0a61024581bcdcf6c2aedec6976b
https://pubmed.ncbi.nlm.nih.gov/15196697
https://pubmed.ncbi.nlm.nih.gov/15196697
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9780306460449
Stimulation of neuronal tissues with neurotransmitters results in the release of the polyunsaturated fatty acids 20:4n6 and 22:6n3. Astroglial cells hydrolyze 20:4n6 and 22:6n3 equally well under both stimulated and basal conditions. Despite the high
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3826644d481506d16c4d7e944de91001
https://doi.org/10.1007/978-1-4615-4861-4_7
https://doi.org/10.1007/978-1-4615-4861-4_7
Publikováno v:
Lipids. 25(4)
This study has utilized radiolabeled analogues of arachidonic acid to study the substrate specificity of elongation of long-chain polyunsaturated fatty acids. Human umbilical vein endothelial cells were incubated for 2-72 hr in medium supplemented wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e98a446e97299ea4e30052bf4ad09175
https://pubmed.ncbi.nlm.nih.gov/2345494
https://pubmed.ncbi.nlm.nih.gov/2345494
Publikováno v:
Alcoholism: Clinical & Experimental Research. 21:1465
We studied the effects of chronic ethanol exposure on the mobilization of polyunsaturated fatty acids stimulated by activation of the type 2A serotonin receptor in C6 glioma cells. In our in vitro model, we prelabeled cells with [ 3 H]arachidonate an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e034082c21b3346cde03670572f627a
https://doi.org/10.1097/00000374-199711000-00017
https://doi.org/10.1097/00000374-199711000-00017
Publikováno v:
Archives of Biochemistry and Biophysics. 274:590-600
Stimulation of vascular endothelial cells with agonists such as histamine and thrombin results in release of arachidonic acid from membrane lipids and subsequent eicosanoid synthesis. As shown previously, the agonist-stimulated deacylation is specifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c52d7590c555d92a7f82fe71ec80eeb0
https://doi.org/10.1016/0003-9861(89)90474-8
https://doi.org/10.1016/0003-9861(89)90474-8