Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Martha Ackerman"'
Autor:
Cutler T. Lewandowski, Md.Wasim Khan, Manel BenAissa, Oleksii Dubrovskyi, Martha Ackerman-Berrier, Mary Jo LaDu, Brian T. Layden, Gregory R.J. Thatcher
Publikováno v:
EBioMedicine, Vol 66, Iss , Pp 103287- (2021)
Background: Therapeutic agents with novel mechanisms of action are needed to combat the growing epidemic of type 2 diabetes (T2D) and related metabolic syndromes. Liver X receptor (LXR) agonists possess preclinical efficacy yet produce side effects d
Externí odkaz:
https://doaj.org/article/5277fbac50654f85b635af85f115f0b3
Autor:
Kiira M. Ratia, Zhengnan Shen, Jesse Gordon-Blake, Hyun Lee, Megan S. Laham, Isabella S. Krider, Nicholas Christie, Martha Ackerman-Berrier, Christopher Penton, Natalie G. Knowles, Soumya Reddy Musku, Jiqiang Fu, Ganga Reddy Velma, Rui Xiong, Gregory R. J. Thatcher
Publikováno v:
Biochemistry. 62:923-933
Autor:
Kiira M. Ratia, Zhengnan Shen, Jesse Gordon-Blake, Hyun Lee, Megan S. Laham, Isabella S. Krider, Nicholas Christie, Martha Ackerman-Berrier, Christopher Penton, Natalie G. Knowles, Soumya Reddy Musku, Jiqiang Fu, Ganga Reddy Velma, Rui Xiong, Gregory R J Thatcher
In aging and disease, cellular NAD+is depleted by catabolism to nicotinamide (NAM) and NAD+supple-mentation is being pursued to enhance human healthspan and lifespan. Activation of nicoti namide phosphoribosyl -transferase (NAMPT), the rate-limiting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f94de410e56d30c94c873c98a4bfc088
https://doi.org/10.1101/2022.10.21.513220
https://doi.org/10.1101/2022.10.21.513220
Discover artwork activities to help you process your past and change your future, in this 10-session artistic journey for women's groupsIf you've ever needed a fresh start or wanted to find a new way to begin to heal from the pain in your life, Creat
Autor:
Manel BenAissa, Md. Wasim Khan, Brian T. Layden, Martha Ackerman-Berrier, Cutler T. Lewandowski, Oleksii Dubrovskyi, Mary Jo LaDu, Gregory R. J. Thatcher
Publikováno v:
EBioMedicine
EBioMedicine, Vol 66, Iss, Pp 103287-(2021)
EBioMedicine, Vol 66, Iss, Pp 103287-(2021)
Background Therapeutic agents with novel mechanisms of action are needed to combat the growing epidemic of type 2 diabetes (T2D) and related metabolic syndromes. Liver X receptor (LXR) agonists possess preclinical efficacy yet produce side effects du
Autor:
Ramesh Bhatt, Linda D. Artman, Chae Hee Kang, Robert G. MacKenzie, Karen E. Asin, Martha Ackerman, Clark Briggs, Donald R. Britton, Peter Curzon, Lisa Bednarz, Michael P. DeNinno, John W. Kebabian, Edwin Gomez, Joel M. Trugman, Robert Schoenleber, James Stittsworth
Publikováno v:
European Journal of Pharmacology. 199:209-219
A68930, (1R,3S)-1-aminomethyl-5,6-dihydroxy-3-phenylisochroman HCl, is a potent (EC50 = 2.5 nM), partial (intrinsic activity = 66% of dopamine) agonist in the fish retina dopamine-sensitive adenylate cyclase model of the D1 dopamine receptor. In the
Autor:
L.Charlie Chen, Kenneth F. Wertman, James Spoonamore, Anna Robinson, Sydney Wilson, David S. Thorpe, Alan Binnie, Martha Ackerman-Berrier, Shelly Wade, Stefan Walle, Helen Yeoman, Qinyuan (Quincey) Wu, A.W. Edith Chan, David Rodwell
Publikováno v:
Biochemical and biophysical research communications. 266(1)
Living systems are mainly composed and regulated by compounds in four biochemical classes and their polymers-nucleotides, carbohydrates, lipids, and amino acids. Early combinatorial chemistry libraries consisted of peptides. The present report descri
Autor:
Martha Ackerman, Adams P, Bhatt R, Robert G. MacKenzie, Steffey Me, Snyder Gl, J S Fink, Barrett Rw, Gomez E
Publikováno v:
European journal of pharmacology. 207(4)
Dopamine is shown to stimulate cAMP accumulation in COS-1 cells via endogenously expressed dopamine D1 receptors. A dissociation of dopamine and beta-adrenoceptor responses is demonstrated by the use of selective antagonists and different desensitiza
Autor:
Herman Stampfli, Lisa Bednarz, Linda D. Artman, John W. Kebabian, Daniel J. Kerkman, Marty C. Johnson, William Montana, Martha Ackerman, Robert G. MacKenzie, Karen E. Asin
Publikováno v:
European journal of pharmacology. 166(3)
A-69024 HBr, 1-(2-bromo-4,5-dimethoxybenzyl)-7-hydroxy-6-methoxy-2-methyl-1,2,3,4-tetrahydroisoquinoline hydrobromide, is a selective antagonist of the dopamine D-1 receptor. A-69024 HBr shows an apparent affinity toward the D-1 receptor (identified