Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Martha A Cady"'
Autor:
Belinda J. Hernandez, Nikolai P. Skiba, Karolina Plössl, Madison Strain, Yutao Liu, Daniel Grigsby, Una Kelly, Martha A. Cady, Vikram Manocha, Arvydas Maminishkis, TeddiJo Watkins, Sheldon S. Miller, Allison Ashley‐Koch, W. Daniel Stamer, Bernhard H. F. Weber, Catherine Bowes Rickman, Mikael Klingeborn
Publikováno v:
Journal of Extracellular Biology, Vol 2, Iss 10, Pp n/a-n/a (2023)
Abstract The retinal pigmented epithelium (RPE) constitutes the outer blood‐retinal barrier, enables photoreceptor function of the eye, and is constantly exposed to oxidative stress. As such, dysfunction of the RPE underlies pathology leading to de
Externí odkaz:
https://doaj.org/article/d61d8d2d0c8f4f56a964ddb524e39f94
Autor:
Thomas A. Ray, Kelly Cochran, Chris Kozlowski, Jingjing Wang, Graham Alexander, Martha A. Cady, William J. Spencer, Philip A. Ruzycki, Brian S. Clark, Annelies Laeremans, Ming-Xiao He, Xiaoming Wang, Emily Park, Ying Hao, Alessandro Iannaccone, Gary Hu, Olivier Fedrigo, Nikolai P. Skiba, Vadim Y. Arshavsky, Jeremy N. Kay
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-20 (2020)
Here the authors present an approach that can reveal the full complement of mRNA isoforms encoded by individual genes, and they identify a major isoform of the retinal degeneration gene CRB1 which functions at the cell-cell junctions of the outer lim
Externí odkaz:
https://doaj.org/article/d7eafb0bbaa4448cab111eaa3196f3ce
Autor:
Abrar Choudhury, Stephen T. Magill, Charlotte D. Eaton, Briana C. Prager, William C. Chen, Martha A. Cady, Kyounghee Seo, Calixto-Hope G. Lucas, Tim J. Casey-Clyde, Harish N. Vasudevan, S. John Liu, Javier E. Villanueva-Meyer, Tai-Chung Lam, Jenny Kan-Suen Pu, Lai-Fung Li, Gilberto Ka-Kit Leung, Danielle L. Swaney, Michael Y. Zhang, Jason W. Chan, Zhixin Qiu, Michael V. Martin, Matthew S. Susko, Steve E. Braunstein, Nancy Ann Oberheim Bush, Jessica D. Schulte, Nicholas Butowski, Penny K. Sneed, Mitchel S. Berger, Nevan J. Krogan, Arie Perry, Joanna J. Phillips, David A. Solomon, Joseph F. Costello, Michael W. McDermott, Jeremy N. Rich, David R. Raleigh
Publikováno v:
Nature genetics, vol 54, iss 5
Nat Genet
Nat Genet
Meningiomas are the most common primary intracranial tumors. There are no effective medical therapies for meningioma patients, and new treatments have been encumbered by limited understanding of meningioma biology. Here, we use DNA methylation profil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16fe497895b27e3b5342d54b19fe322d
https://doi.org/10.1038/s41588-022-01061-8
https://doi.org/10.1038/s41588-022-01061-8
Autor:
Michael R. Wilson, Hidekazu Tomimoto, Joseph L. DeRisi, Yuichiro, Kelsey C. Zorn, Martha A Cady, Sabrina A Mann, Koichi Miyashita, Atsushi Niwa, Hidehiro Ishikawa, Masayuki Maeda, Akihiro Shindo, Akira Taniguchi, Caleigh Mandel-Brehm
Publikováno v:
European Journal of Neurology. 28:4261-4266
BACKGROUND AND PURPOSE The aim of this study was to identify the long-term radiological changes, autoantibody specificities, and clinical course in a patient with kelch-like protein 11 (KLHL11)-associated paraneoplastic neurological syndrome (PNS). M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2795578bc3b492a43fd22d6b448552d3
https://doi.org/10.1111/ene.15120
https://doi.org/10.1111/ene.15120
Autor:
Michael Landowski, Mikael Klingeborn, Daniel Grigsby, Jian Liu, Una Kelly, Alan T. Remaley, Martha A. Cady, Nikolai P. Skiba, Catherine Bowes Rickman
Publikováno v:
J Biol Chem
Strong evidence suggests that dysregulated lipid metabolism involving dysfunction of the retinal pigmented epithelium (RPE) underlies the pathogenesis of age-related macular degeneration (AMD), the leading cause of irreversible blindness in the elder
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5aaac1ae76d30160e93db2b00e01d3e
https://doi.org/10.1074/jbc.ra119.012305
https://doi.org/10.1074/jbc.ra119.012305
Autor:
Xiaoming Wang, Thomas A. Ray, Jingjing Wang, Alessandro Iannaccone, Nikolai P. Skiba, Chris Kozlowski, Jeremy N. Kay, William J. Spencer, Annelies Laeremans, Vadim Y. Arshavsky, Martha A. Cady, Olivier Fedrigo, Brian S. Clark, Gary Hu, Kelly Cochran, Ming-Xiao He, Graham Alexander, Philip A. Ruzycki, Emily Park, Ying Hao
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-20 (2020)
Nature Communications
Nature Communications
Genes encoding cell-surface proteins control nervous system development and are implicated in neurological disorders. These genes produce alternative mRNA isoforms which remain poorly characterized, impeding understanding of how disease-associated mu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a0afac6e60470329e86ee515149bbb9
https://doaj.org/article/d7eafb0bbaa4448cab111eaa3196f3ce
https://doaj.org/article/d7eafb0bbaa4448cab111eaa3196f3ce
Autor:
Wolfgang Baehr, Cecilia D. Gerstner, Ali Sakawa Sharif, Jeanne M. Frederick, Martha A. Cady, Vadim Y. Arshavsky, Christina Anne Mitchell, Guoxin Ying
Publikováno v:
The Journal of Biological Chemistry
INPP5E, also known as pharbin, is a ubiquitously expressed phosphatidylinositol polyphosphate 5-phosphatase that is typically located in the primary cilia and modulates the phosphoinositide composition of membranes. Mutations to or loss of INPP5E is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a678b53f03ba002421b1df8a573c65a1
http://europepmc.org/articles/PMC8047226
http://europepmc.org/articles/PMC8047226
Autor:
Joanna J. Phillips, Ophir D. Klein, Stephen Magill, Shawn L. Hervey-Jumper, David R. Raleigh, Martha A Cady, Brisa Palikuqi, Aparna Bhaduri, C.H. Lucas, Peter J Dickinson, Abrar Choudhury, Elizabeth E. Crouch
Publikováno v:
Neuro-Oncology. 23:vi26-vi27
BACKGROUND Meningiomas are the most common primary intracranial tumors in humans and dogs, but biologic drivers and cell types underlying meningeal tumorigenesis are incompletely understood. Here we integrate meningioma single-cell RNA sequencing wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f5c0b3bad59962885152e79522c4bf69
https://doi.org/10.1093/neuonc/noab196.101
https://doi.org/10.1093/neuonc/noab196.101
Autor:
Sarah Hiles, Nikolai P. Skiba, William J. Spencer, Laurie L. Molday, Nancy J. Philp, Vadim Y. Arshavsky, Robert S. Molday, Will J. Thompson, Tylor R. Lewis, Martha A. Cady, John Y. S. Han
Publikováno v:
Molecular & Cellular Proteomics : MCP
The outer segment (OS) organelle of vertebrate photoreceptors is a highly specialized cilium evolved to capture light and initiate light response. The plasma membrane which envelopes the OS plays vital and diverse roles in supporting photoreceptor fu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2968f2d098057334e3d5f285280fd842
https://pubmed.ncbi.nlm.nih.gov/33933680
https://pubmed.ncbi.nlm.nih.gov/33933680
Autor:
Vadim Y. Arshavsky, Christina Anne Mitchell, Ali Sakawa Sharif, Wolfgang Baehr, Guoxin Ying, Martha A. Cady, Jeanne M. Frederick, Cecilia D. Gerstner
INPP5E (pharbin) is a ubiquitously-expressed, farnesylated phosphatidylinositol polyphosphate 5’-phosphatase which modulates the phosphoinositide composition of membranes. INPP5E resides in primary cilia, and mutations or loss of INPP5E are associa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c717a1378e0213081d3454a045b163d
https://doi.org/10.1101/2020.11.29.403030
https://doi.org/10.1101/2020.11.29.403030
