Zobrazeno 1 - 10 of 13 pro vyhledávání: '"Marten Bernhardt"'
1
X-Ray Structural Analysis of Single Adult Cardiomyocytes: Tomographic Imaging and Microdiffraction
Autor: Jan-David Nicolas, Marten Bernhardt, Karl Toischer, Marius Reichardt, Tim Salditt, Charlotte Neuhaus
Publikováno v: Biophysical journal 119(7), 1309-1323 (2020). doi:10.1016/j.bpj.2020.08.019
Biophysical Journal
We present a multiscale imaging approach to characterize the structure of isolated adult murine cardiomyocytes based on a combination of full-field three-dimensional coherent x-ray imaging and scanning x-ray diffraction. Using these modalities, we pr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87e36f9e25a39fcf8936d9478caddb84
https://doi.org/10.1016/j.bpj.2020.08.019
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2
Combined optical fluorescence microscopy and X-ray tomography reveals substructures in cell nuclei in 3D
Autor: Andrew Wittmeier, Marten Bernhardt, Anna-Lena Robisch, Chiara Cassini, Markus Osterhoff, Tim Salditt, Sarah Köster
Publikováno v: Biomedical optics express 13(9), 4954-4969 (2022). doi:10.1364/BOE.462493
Biomed Opt Express
Biomedical optics express 13(9), 4954 - 4969 (2022). doi:10.1364/BOE.462493
The function of a biological cell is fundamentally defined by the structural architecture of packaged DNA in the nucleus. Elucidating information about the packaged DNA
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e6168d1df72b1f1c86902aaa7566cb7
https://bib-pubdb1.desy.de/record/582580
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3
X-ray diffraction imaging of cardiac cells and tissue
Autor: Tim Salditt, Susanne F. Schlick, Amara Khan, Malte Tiburcy, Karl Toischer, Frauke Alves, Jan-David Nicolas, Marten Bernhardt, Andrea Markus, Wolfram-Hubertus Zimmermann
Publikováno v: Progress in biophysics & molecular biology 144, 151-165 (2019). doi:10.1016/j.pbiomolbio.2018.05.012
With the development of advanced focusing optics for x-rays, we can now use x-ray beams with spot sizes in the micro- or nanometer range to scan cells and large areas of tissues and continuously record the diffraction signals. From this data, x-ray s
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c69411753758aacf7c06bd8a395a4c80
https://doi.org/10.1016/j.pbiomolbio.2018.05.012
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4
X-ray structural analysis of single adult cardiomyocytes: tomographic imaging and micro-diffraction
Autor: Karl Toischer, Tim Salditt, Marius Reichardt, C. Neuhaus, J-D. Nicolas, Marten Bernhardt
We present a multi-scale imaging approach to characterize the structure of isolated adult murine cardiomyocytes based on a combination of full-field three-dimensional (3d) coherent x-ray imaging and scanning x-ray diffraction. Using these modalities,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::586c658afccb7d01568ede5fbcad9fc7
https://doi.org/10.1101/2020.07.08.193771
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7
Scanning X-ray diffraction on cardiac tissue: automatized data analysis and processing
Autor: Tim Salditt, Jan-David Nicolas, Frauke Alves, Manfred Burghammer, M. Andrea Markus, Marten Bernhardt
Publikováno v: Journal of Synchrotron Radiation. 24:1163-1172
A scanning X-ray diffraction study of cardiac tissue has been performed, covering the entire cross section of a mouse heart slice. To this end, moderate focusing by compound refractive lenses to micrometer spot size, continuous scanning, data acquisi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd744f3327ce97195ab9b4a08b223e50
https://doi.org/10.1107/s1600577517011936
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8
Combined scanning X-ray diffraction and holographic imaging of cardiomyocytes
Autor: Martin Krenkel, Stefan Luther, Marten Bernhardt, Claudia Richter, Jan-David Nicolas, Tim Salditt
Publikováno v: Journal of Applied Crystallography. 50:612-620
This article presents scanning small-angle X-ray scattering (SAXS) experiments on the actomyosin assemblies in freeze-dried neo-natal rat cardiac muscle cells. By scanning the cells through a sub-micrometre focused beam, the local structure and filam
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d4185a575e14cf2fe5455a7ed455b825
https://doi.org/10.1107/s1600576717003351
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9
A beamline-compatible STED microscope for combined visible-light and X-ray studies of biological matter
Autor: Haugen Mittelstädt, Tim Salditt, Michael Sprung, Markus Osterhoff, Sarah Köster, Andrew Wittmeier, Matthias Reuss, Benjamin Harke, Jan David Nicolas, Marten Bernhardt
Publikováno v: Journal of synchrotron radiation. 26(Pt 4)
A dedicated stimulated emission depletion (STED) microscope had been designed and implemented into the Göttingen Instrument for Nano-Imaging with X-rays (GINIX) at the synchrotron beamline P10 of the PETRA III storage ring (DESY, Hamburg). The micro
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dfc96e50154bbbd806b65aa6b2ecd9c
https://pubmed.ncbi.nlm.nih.gov/31274438
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10
X-Ray Micro- and Nanodiffraction Imaging on Human Mesenchymal Stem Cells and Differentiated Cells
Autor: Ana Diaz, Florian Rehfeldt, Tim Salditt, Marten Bernhardt, Marius Priebe, Carina Wollnik, Markus Osterhoff
Publikováno v: Biophysical journal 110(3), 680-690 (2016). doi:10.1016/j.bpj.2015.12.017
Adult human mesenchymal stem cells show structural rearrangements of their cytoskeletal network during mechanically induced differentiation toward various cell types. In particular, the alignment of acto-myosin fibers is cell fate-dependent and can s
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cd28ed1077dbce120092cea644d1307
https://bib-pubdb1.desy.de/record/311829
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