Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Marten Beeg"'
Autor:
Nico Martarelli, Michela Capurro, Gizem Mansour, Ramina Vossoughi Jahromi, Arianna Stella, Roberta Rossi, Emanuele Longetti, Barbara Bigerna, Marco Gentili, Ariele Rosseto, Riccardo Rossi, Chiara Cencini, Carla Emiliani, Sabata Martino, Marten Beeg, Marco Gobbi, Enrico Tiacci, Brunangelo Falini, Francesco Morena, Vincenzo Maria Perriello
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 13, p 7231 (2024)
Chimeric antigen receptor (CAR) T cells represent a revolutionary immunotherapy that allows specific tumor recognition by a unique single-chain fragment variable (scFv) derived from monoclonal antibodies (mAbs). scFv selection is consequently a funda
Externí odkaz:
https://doaj.org/article/815a0d706f614298a3cf7e99120bbe88
Autor:
Francesca Re, Sofia Giorgetti, Barbara Biondi, Stefano Scapin, Francesco Mantegazza, Valeria Cassina, Silvia Maria Sesana, Laura Rizzi, Ivano Eberini, Luca Palazzolo, Marten Beeg, Marco Gobbi, Marco Sardina, Massimo Masserini
Publikováno v:
Annals of Medicine, Vol 55, Iss 1 (2023)
AbstractAim The effect of liposomes bi-functionalized with phosphatidic acid and with a synthetic peptide derived from human apolipoprotein E has been evaluated on the aggregation features of different amyloidogenic proteins: human Amyloid β1–40 (
Externí odkaz:
https://doaj.org/article/f28ca372cf6d4d4ab6a34ae319ebc629
Autor:
Irene Cattaneo, Sylvie Choblet, Rut Valgardsdottir, Muriel Roth, Annamaria Massafra, Marten Beeg, Marco Gobbi, Martine Duonor-Cerutti, Josée Golay
Publikováno v:
Antibodies, Vol 13, Iss 1, p 15 (2024)
We designed, produced, and purified a novel IgG1-like, bispecific antibody (bsAb) directed against B-cell maturation antigen (BCMA), expressed by multiple myeloma (MM) cells, and an immune checkpoint inhibitor (ICI), PDL1, expressed in the MM microen
Externí odkaz:
https://doaj.org/article/6fa362dcbed34f4f9ee34e7988391880
Autor:
Daniela Iaconis, Licia Bordi, Giulia Matusali, Carmine Talarico, Candida Manelfi, Maria Candida Cesta, Mara Zippoli, Francesca Caccuri, Antonella Bugatti, Alberto Zani, Federica Filippini, Laura Scorzolini, Marco Gobbi, Marten Beeg, Arianna Piotti, Monica Montopoli, Veronica Cocetta, Silvia Bressan, Enrico M. Bucci, Arnaldo Caruso, Emanuele Nicastri, Marcello Allegretti, Andrea R. Beccari
Publikováno v:
Cell Death and Disease, Vol 13, Iss 5, Pp 1-9 (2022)
Abstract The new coronavirus SARS-CoV-2 is the causative agent of the COVID-19 pandemic, which so far has caused over 6 million deaths in 2 years, despite new vaccines and antiviral medications. Drug repurposing, an approach for the potential applica
Externí odkaz:
https://doaj.org/article/9f7ad91081cf4ba8bb1f706204ee8be2
Autor:
Marten Beeg, Sara Baroni, Arianna Piotti, Alessia Porta, Ada De Luigi, Alfredo Cagnotto, Marco Gobbi, Luisa Diomede, Mario Salmona
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 15, p 12146 (2023)
We developed and validated a technology platform for designing and testing peptides inhibiting the infectivity of SARS-CoV-2 spike protein-based pseudoviruses. This platform integrates target evaluation, in silico inhibitor design, peptide synthesis,
Externí odkaz:
https://doaj.org/article/8b485bf67f304286932a246c4682d0fc
Autor:
Marten Beeg, Cesare Burti, Eleonora Allocati, Clorinda Ciafardini, Rita Banzi, Alessandro Nobili, Flavio Caprioli, Silvio Garattini, Marco Gobbi
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Measurements of serum concentrations of therapeutic antibodies and anti-drug antibodies (ADA) can support clinical decisions for the management of non-responders, optimizing the therapy. In the present study we compared the results obtained
Externí odkaz:
https://doaj.org/article/7c5b89138f34411fb9ab6205b28ca5f1
Autor:
Michela Bollati, Luisa Diomede, Toni Giorgino, Carmina Natale, Elisa Fagnani, Irene Boniardi, Alberto Barbiroli, Rebecca Alemani, Marten Beeg, Marco Gobbi, Ana Fakin, Eloise Mastrangelo, Mario Milani, Gianluca Presciuttini, Edi Gabellieri, Patrizia Cioni, Matteo de Rosa
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss , Pp 6355-6365 (2021)
Gelsolin comprises six homologous domains, named G1 to G6. Single point substitutions in this protein are responsible for AGel amyloidosis, a hereditary disease causing progressive corneal lattice dystrophy, cutis laxa, and polyneuropathy. Although s
Externí odkaz:
https://doaj.org/article/28c0fa7cd36a48168031138ec41efe6d
Autor:
Michela Bollati, Kaliroi Peqini, Luigi Barone, Carmina Natale, Marten Beeg, Marco Gobbi, Luisa Diomede, Michelangelo Trucchi, Matteo de Rosa, Sara Pellegrino
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 22, p 13973 (2022)
Gelsolin amyloidosis (AGel) is characterized by multiple systemic and ophthalmic features resulting from pathological tissue deposition of the gelsolin (GSN) protein. To date, no cure is available for the treatment of any form of AGel. More than ten
Externí odkaz:
https://doaj.org/article/7db0697bd1fe4a8d9d78a8fd9c2926f4
Autor:
Luisa Diomede, Sara Baroni, Ada De Luigi, Arianna Piotti, Jacopo Lucchetti, Claudia Fracasso, Luca Russo, Valerio Bonaldo, Nicolò Panini, Federica Filippini, Fabio Fiordaliso, Alessandro Corbelli, Marten Beeg, Massimo Pizzato, Francesca Caccuri, Marco Gobbi, Emiliano Biasini, Arnaldo Caruso, Mario Salmona
Publikováno v:
Viruses, Vol 13, Iss 9, p 1745 (2021)
The rapid spread of the pandemic caused by the SARS-CoV-2 virus has created an unusual situation, with rapid searches for compounds to interfere with the biological processes exploited by the virus. Doxycycline, with its pleiotropic effects, includin
Externí odkaz:
https://doaj.org/article/8667a2a4d1404f80bdea527d4cbd5fc9
Publikováno v:
Biomolecules, Vol 11, Iss 6, p 855 (2021)
The phytotherapeutic properties of Glycyrrhiza glabra (licorice) extract are mainly attributed to glycyrrhizin (GR) and glycyrrhetinic acid (GA). Among their possible pharmacological actions, the ability to act against viruses belonging to different
Externí odkaz:
https://doaj.org/article/9677a1efbb1f4dacb7792fb669ad2fdc