Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Marten A, Hoeksema"'
Autor:
Nathalie A. Reilly, Friederike Sonnet, Koen F. Dekkers, Joanneke C. Kwekkeboom, Lucy Sinke, Stan Hilt, Hayat M. Suleiman, Marten A. Hoeksema, Hailiang Mei, Erik W. van Zwet, Bart Everts, Andreea Ioan-Facsinay, J. Wouter Jukema, Bastiaan T. Heijmans
Publikováno v:
iScience, Vol 27, Iss 4, Pp 109496- (2024)
Summary: T cells are the most common immune cells in atherosclerotic plaques, and the function of T cells can be altered by fatty acids. Here, we show that pre-exposure of CD4+ T cells to oleic acid, an abundant fatty acid linked to cardiovascular ev
Externí odkaz:
https://doaj.org/article/5f40b85a5de4481da650e5538f4737d5
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/998cc91a33e841dab8db96c7b1ccf104
Autor:
Suzanne A.E. van Wouw, Marlene van den Berg, Maroua El Ouraoui, Amber Meurs, Jenina Kingma, Roelof Ottenhoff, Melanie Loix, Marten A. Hoeksema, Koen Prange, Gerard Pasterkamp, Jerome J.A. Hendriks, Jeroen F.J. Bogie, Jan B. van Klinken, Frederic M. Vaz, Aldo Jongejan, Menno P.J. de Winther, Noam Zelcer
Publikováno v:
Journal of Lipid Research, Vol 64, Iss 2, Pp 100325- (2023)
Lysoplasmalogens are a class of vinyl ether bioactive lipids that have a central role in plasmalogen metabolism and membrane fluidity. The liver X receptor (LXR) transcription factors are important determinants of cellular lipid homeostasis owing to
Externí odkaz:
https://doaj.org/article/5be45c9062f1454c8a49dcd0a8d8b7ff
Autor:
Lisa Willemsen, Hung-Jen Chen, Cindy P. A. A. van Roomen, Guillermo R. Griffith, Ricky Siebeler, Annette E. Neele, Jeffrey Kroon, Marten A. Hoeksema, Menno P. J. de Winther
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
Macrophages are critical components of atherosclerotic lesions and their pro- and anti-inflammatory responses influence atherogenesis. Type-I interferons (IFNs) are cytokines that play an essential role in antiviral responses and inflammatory activat
Externí odkaz:
https://doaj.org/article/69458ffd899140378f46c0bb4e3955bd
Autor:
Zeyang Shen, Rick Z Li, Thomas A Prohaska, Marten A Hoeksema, Nathan J Spann, Jenhan Tao, Gregory J Fonseca, Thomas Le, Lindsey K Stolze, Mashito Sakai, Casey E Romanoski, Christopher K Glass
Publikováno v:
eLife, Vol 11 (2022)
Regulation of gene expression requires the combinatorial binding of sequence-specific transcription factors (TFs) at promoters and enhancers. Prior studies showed that alterations in the spacing between TF binding sites can influence promoter and enh
Externí odkaz:
https://doaj.org/article/98d44d7ff9f64f50bf3ced74f1b45425
Autor:
Annette E. Neele, Hung-Jen Chen, Marion J. J. Gijbels, Saskia van der Velden, Marten A. Hoeksema, Marieke C. S. Boshuizen, Jan Van den Bossche, Anton T. Tool, Hanke L. Matlung, Timo K. van den Berg, Esther Lutgens, Menno P. J. de Winther
Publikováno v:
Frontiers in Immunology, Vol 11 (2021)
Macrophages define a key component of immune cells present in atherosclerotic lesions and are central regulators of the disease. Since epigenetic processes are important in controlling macrophage function, interfering with epigenetic pathways in macr
Externí odkaz:
https://doaj.org/article/a428a6da91984e6f8be4eb28adb8b03a
Autor:
Jan Van den Bossche, Jeroen Baardman, Natasja A. Otto, Saskia van der Velden, Annette E. Neele, Susan M. van den Berg, Rosario Luque-Martin, Hung-Jen Chen, Marieke C.S. Boshuizen, Mohamed Ahmed, Marten A. Hoeksema, Alex F. de Vos, Menno P.J. de Winther
Publikováno v:
Cell Reports, Vol 17, Iss 3, Pp 684-696 (2016)
Macrophages are innate immune cells that adopt diverse activation states in response to their microenvironment. Editing macrophage activation to dampen inflammatory diseases by promoting the repolarization of inflammatory (M1) macrophages to anti-inf
Externí odkaz:
https://doaj.org/article/fa408860cfc742feaf109656fe022033
Autor:
Marten A Hoeksema, Marion JJ Gijbels, Jan Van den Bossche, Saskia van der Velden, Ayestha Sijm, Annette E Neele, Tom Seijkens, J Lauran Stöger, Svenja Meiler, Marieke CS Boshuizen, Geesje M Dallinga‐Thie, Johannes HM Levels, Louis Boon, Shannon E Mullican, Nathanael J Spann, Jack P Cleutjens, Chris K Glass, Mitchell A Lazar, Carlie JM de Vries, Erik AL Biessen, Mat JAP Daemen, Esther Lutgens, Menno PJ de Winther
Publikováno v:
EMBO Molecular Medicine, Vol 6, Iss 9, Pp 1124-1132 (2014)
Abstract Macrophages are key immune cells found in atherosclerotic plaques and critically shape atherosclerotic disease development. Targeting the functional repertoire of macrophages may hold novel approaches for future atherosclerosis management. H
Externí odkaz:
https://doaj.org/article/c1022f732a3f48b2bc9b04afedbfc806
Autor:
Zeyang Shen, Rick Z Li, Thomas A Prohaska, Marten A Hoeksema, Nathan J Spann, Jenhan Tao, Gregory J Fonseca, Thomas Le, Lindsey K Stolze, Mashito Sakai, Casey E Romanoski, Christopher K Glass
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4175c3566ce7d3c1ecff2e2adfb25f9d
https://doi.org/10.7554/elife.70878.sa2
https://doi.org/10.7554/elife.70878.sa2
