Zobrazeno 1 - 10
of 167
pro vyhledávání: '"Marteinn"'
Autor:
Tal Levy, Kai Voeltzke, Laura Hruby, Khawla Alasad, Zuelal Bas, Marteinn Snaebjörnsson, Ran Marciano, Katerina Scharov, Mélanie Planque, Kim Vriens, Stefan Christen, Cornelius M. Funk, Christina Hassiepen, Alisa Kahler, Beate Heider, Daniel Picard, Jonathan K. M. Lim, Anja Stefanski, Katja Bendrin, Andres Vargas-Toscano, Ulf D. Kahlert, Kai Stühler, Marc Remke, Moshe Elkabets, Thomas G. P. Grünewald, Andreas S. Reichert, Sarah-Maria Fendt, Almut Schulze, Guido Reifenberger, Barak Rotblat, Gabriel Leprivier
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract Energetic stress compels cells to evolve adaptive mechanisms to adjust their metabolism. Inhibition of mTOR kinase complex 1 (mTORC1) is essential for cell survival during glucose starvation. How mTORC1 controls cell viability during glucose
Externí odkaz:
https://doaj.org/article/b77120ef8e324fda80f5122560600dc1
Autor:
Brynja D. Sigurpalsdottir, Olafur A. Stefansson, Guillaume Holley, Doruk Beyter, Florian Zink, Marteinn Þ. Hardarson, Sverrir Þ. Sverrisson, Nina Kristinsdottir, Droplaug N. Magnusdottir, Olafur Þ. Magnusson, Daniel F. Gudbjartsson, Bjarni V. Halldorsson, Kari Stefansson
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-21 (2024)
Abstract Background Long-read sequencing can enable the detection of base modifications, such as CpG methylation, in single molecules of DNA. The most commonly used methods for long-read sequencing are nanopore developed by Oxford Nanopore Technologi
Externí odkaz:
https://doaj.org/article/3a4e0a5518454358a898c2f417057ccb
Autor:
Snaedis Kristmundsdottir, Hakon Jonsson, Marteinn T. Hardarson, Gunnar Palsson, Doruk Beyter, Hannes P. Eggertsson, Arnaldur Gylfason, Gardar Sveinbjornsson, Guillaume Holley, Olafur A. Stefansson, Gisli H. Halldorsson, Sigurgeir Olafsson, Gudny. A. Arnadottir, Pall I. Olason, Ogmundur Eiriksson, Gisli Masson, Unnur Thorsteinsdottir, Thorunn Rafnar, Patrick Sulem, Agnar Helgason, Daniel F. Gudbjartsson, Bjarni V. Halldorsson, Kari Stefansson
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract Microsatellites are polymorphic tracts of short tandem repeats with one to six base-pair (bp) motifs and are some of the most polymorphic variants in the genome. Using 6084 Icelandic parent-offspring trios we estimate 63.7 (95% CI: 61.9–65
Externí odkaz:
https://doaj.org/article/113e73b990e84e01a7edcf95e209fb66
Autor:
Hidenobu Miyazawa, Marteinn T Snaebjornsson, Nicole Prior, Eleni Kafkia, Henrik M Hammarén, Nobuko Tsuchida-Straeten, Kiran R Patil, Martin Beck, Alexander Aulehla
Publikováno v:
eLife, Vol 11 (2022)
How cellular metabolic state impacts cellular programs is a fundamental, unresolved question. Here, we investigated how glycolytic flux impacts embryonic development, using presomitic mesoderm (PSM) patterning as the experimental model. First, we ide
Externí odkaz:
https://doaj.org/article/0c5a0191332144eb9bf2c9c3950be861
Autor:
Jessica Denise Schwarz, Sören Lukassen, Pranjali Bhandare, Lorenz Eing, Marteinn Thor Snaebjörnsson, Yiliam Cruz García, Jan Philipp Kisker, Almut Schulze, Elmar Wolf
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Cellular growth is a fundamental process of life and must be precisely controlled in multicellular organisms. Growth is crucially controlled by the number of functional ribosomes available in cells. The production of new ribosomes depends critically
Externí odkaz:
https://doaj.org/article/89c05fdd745a45f78a80af68cbaedfcd
Autor:
Hannes P. Eggertsson, Snaedis Kristmundsdottir, Doruk Beyter, Hakon Jonsson, Astros Skuladottir, Marteinn T. Hardarson, Daniel F. Gudbjartsson, Kari Stefansson, Bjarni V. Halldorsson, Pall Melsted
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-8 (2019)
Structural variants may be omitted in sequence analysis despite their importance in genome variation and phenotypic impact. Here the authors present GraphTyper2, which uses pangenome graphs to genotype structural variants using short-reads and can be
Externí odkaz:
https://doaj.org/article/cd77ec3f22c54b3da55a42242e739711
Autor:
María Victoria Ruiz-Pérez, Lourdes Sainero-Alcolado, Ganna Oliynyk, Isabell Matuschek, Nicola Balboni, S.J. Kumari A. Ubhayasekera, Marteinn Thor Snaebjornsson, Kamil Makowski, Kristina Aaltonen, Daniel Bexell, Dolors Serra, Roland Nilsson, Jonas Bergquist, Almut Schulze, Marie Arsenian-Henriksson
Publikováno v:
iScience, Vol 24, Iss 2, Pp 102128- (2021)
Summary: Many metabolic pathways, including lipid metabolism, are rewired in tumors to support energy and biomass production and to allow adaptation to stressful environments. Neuroblastoma is the second deadliest solid tumor in children. Genetic abe
Externí odkaz:
https://doaj.org/article/fdcde282d39e41aa9c4af63f5a3e2e3b
Publikováno v:
Experimental and Molecular Medicine, Vol 50, Iss 4, Pp 1-16 (2018)
Cancer: Linking cancer signaling and metabolism Further investigations into how multifunctional metabolic enzymes affect cancer development is vital to fully understand and treat the disease. Certain cancer molecules can tap into and ‘rewire’ the
Externí odkaz:
https://doaj.org/article/d57442b111514ede880667937c682701
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